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Pitt, WashU awarded $10.7 Million for Alzheimer's disease genetic research


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IMAGE: Professor of human genetics and epidemiology, University of Pittsburgh Graduate School of Public Health.
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Credit: University of Pittsburgh
PITTSBURGH, May 5, 2021 - Despite decades of research and investment, the genetic underpinnings of Alzheimer s disease are still largely unknown, stymieing drug development and early diagnosis efforts. A new $10.7 million, five-year project led by the University of Pittsburgh Graduate School of Public Health and Washington University School of Medicine in St. Louis aims to change that with the first comprehensive study using whole genome sequencing to address a critical gap in knowledge about the disease.
With funding from the National Institute on Aging, the research team plans to identify the genetic variants, genes and pathways that lead to formation of plaques and tangles, two specific biomarkers that begin accumulating in the brains of people with Alzheimer s 15 to 25 years before the ....

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New research shows breast cancer treatment in patients over age 70 can be safely reduced


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IMAGE: Surgical oncologist at UPMC Hillman Cancer Center and attending surgeon in the Department of Surgery, University of Pittsburgh.
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Credit: UPMC
PITTSBURGH, April 15, 2021 - Oncologists faced with treating older women with breast cancer often must decide if the treatment may be more detrimental than the cancer. A study published today in
JAMA Network Open by researchers at UPMC Hillman Cancer Center and the University of Pittsburgh School of Medicine sheds new light on this choice and suggests the rate of cancer recurrence or survival may be no different in treated vs. untreated elderly patients diagnosed in the early stages of the cancer diagnosed most commonly in women. ....

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