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P=0.01). More adverse events occurred with dexamethasone than with placebo. However, repeat surgery for hematoma recurrence was performed less frequently when dexamethasone was used (1.7%) than placebo (7.1%). Chronic subdural hematoma has been steadily increasing in frequency over the past decades, Hutchinson said. Patients affected are often frail and have other co-existing medical conditions. Since the 1970s, dexamethasone has been used as a drug alongside or instead of surgery with a few studies reporting good results. The findings reduce the enthusiasm for treating chronic subdural hematomas with glucocorticoids, observed New England Journal of Medicine deputy editor Allan Ropper, MD, in an accompanying editorial. ....