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Disrupting a core metabolic process in T cells may improve their therapeutic efficacy sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.
Scientists Improve Anti-Tumor Power of CAR-T Cells insideprecisionmedicine.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from insideprecisionmedicine.com Daily Mail and Mail on Sunday newspapers.
Among available immunotherapies, the use of «CAR-T» cells is proving extremely effective against certain blood cancers, but only in half of patients. A main reason for this is the premature dysfunction of these immune cells, which have been artificially modified in vitro. A team from the Universities of Geneva (UNIGE), Lausanne (UNIL), the Geneva University Hospitals (HUG) and the Vaud University Hospital (CHUV), all part of the Swiss Cancer Center Léman (SCCL), has discovered how to prolong the functionality of CAR-T cells. By inhibiting a very specific metabolic mechanism, the team has succeeded in creating CAR-T cells with enhanced immune memory, capable of fighting tumour cells for much longer. These are very promising results, to be read in the journal Nature. ....
Disrupting a core metabolic process in T cells may improve their therapeutic efficacy phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.
Boosting T Cell Therapy by Disrupting Core Metabolic Process miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.