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Mini-kidneys help understand the link between diabetes and severe COVID-19

A team of scientists including at Karolinska Institutet has used mini-kidneys simulating those of diabetic patients to further our understanding of the link between diabetes and COVID-19. The researchers found that diabetic mini-kidneys have a higher susceptibility to SARS-CoV-2 infection than non-diabetic mini-kidneys. The study, which is published in the journal Cell Metabolism, also identified genetic evidence for the essential role of the ACE2 receptor in COVID-19. ....

United Kingdom , Karolinska Institutet , Josef Penninger , Megan Stanifer , Elena Garreta , Ali Mirazimi , Institute Of Health Carlos , University Of Florida , Institute For Bioengineering Of Catalonia , Institute Of Bioengineering Catalonia , Austrian Academy Of Sciences , Department Of Laboratory Medicine , Foundation Banco Bilbao Vizcaya , Swedish Research Council , University Of British Columbia , European Research Council , Institute Of Molecular Biotechnology , Laboratory Medicine , Professor Nuria Montserrat , Life Sciences Institute , British Columbia , Molecular Biotechnology , Austrian Academy , Health Carlos , Apeiron Biologics ,