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Secarna Pharmaceuticals Announces Publication of New Preclinical Data Showing Durable Antitumor Activity of LNAplus(TM)-Based ASOs that Both Stimulate the Innate Immune System and Suppress PD-L1 Expression

Secarna Pharmaceuticals Announces Publication of New Preclinical Data Showing Durable Antitumor Activity of LNAplus(TM)-Based ASOs that Both Stimulate the Innate Immune System and Suppress PD-L1 Expression
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Alfred Zippelius , Mikael Pittet , Alexander Gebauer , Secarna Lnaplus , Frank Jaschinski , University Of Geneva , Department Of Pathology , Department Of Biomedicine , Secarna Pharmaceuticals , Secarna Pharmaceuticals Gmbh Co , Basel University , Secarna Pharmaceuticals Gmbh , Chief Scientific Officer , United States Wire Group ,

Researchers Identified A Gene That Leads To T Cell Exhaustion, A Discovery That May Pave The Way For More Effective Cancer Immunotherapies

T lymphocytes, also known as T cells, play a critical role in our immune system s battle against cancer cells. However, during this fight, it is not uncommon for T cells to become exhausted. So, overcoming T ....

Alfred Zippelius , University Of Basel ,

Researchers identify a gene that drives T lymphocytes to exhaustion

A research group funded by the Swiss National Science Foundation has identified a gene that drives T lymphocytes to exhaustion. This opens up new approaches for more effective immunotherapies. ....

Marcel Trefny , Alfred Zippelius , Emily Henderson , Nature Communications , Department Of Biomedicine , Swiss National Science Foundation , University Of Basel , University Hospital Basel , Industry Focus , Immune Response , Immune System ,