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New insight into how platelets help resolve bacterial lung inflammation

Treating patients with acute respiratory failure is a constant challenge in intensive care medicine. In most cases, the underlying cause is lung inflammation triggered by a bacterial infection or - more rarely, despite being frequently observed at present due to the corona pandemic - a viral infection. ....

City Of , United Kingdom , Jan Rossaint , Alexander Zarbock , Emily Henderson , Prof Jan Rossaint , Prof Alexander Zarbock , Fluorescence Microscopy , Immune System , Intensive Care , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , எமிலி ஹென்டர்சன் ,

How platelets help resolve lung inflammation

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IMAGE: Platelets (red) interacting with regulatory T cells (yellow) in the bacterially inflamed lung tissue of a mouse. Researchers examined the living tissue using confocal fluorescence microscopy.
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Credit: Rossaint et al./JExpMed 2021
Treating patients with acute respiratory failure is a constant challenge in intensive care medicine. In most cases, the underlying cause is lung inflammation triggered by a bacterial infection or - more rarely, despite being frequently observed at present due to the corona pandemic - a viral infection. During the inflammation, cells of the immune system - the white blood cells - migrate to the lungs and fight the pathogens. At the same time, however, they also cause collateral damage in the lung tissue. If the inflammatory reaction is not resolved in time, this can result in chronic inflammation with permanent impairment of lung function. Together with colleagues from London, Madrid and Munich, a resear ....

City Of , United Kingdom , Jan Rossaint , Alexander Zarbock , Prof Jan Rossaint , Prof Alexander Zarbock , Medicine Health , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , மருந்து ஆரோக்கியம் ,