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Making embryos: a new way?


Making embryos: a new way?
Appeared in BioNews 1091
Recently there have been some phenomenal reports describing the ability to generate human embryo-like entities directly from stem cells, circumventing the need for egg and sperm. In the same week, researchers from Israel reported the development of post-implantation mouse embryos outside of the uterus to the mid-point of mouse pregnancy; an achievement previously firmly within the realm of science fiction. The work is clearly at the leading edge of cell and developmental biology and challenges the paradigms of what it takes to create an embryo. However, like many ground-breaking studies, it is essential to reflect on what lies beneath. ....

South Australia , United States , United Kingdom , University Of Texas , Nicolas Rivron , Alejandro Aguilera Castrejon , Leqian Yu , Magdalena Zernicka Goetz , Roger Sturmey , Hull York Medical School , Leibniz University , Australian Regenerative Medicine Institute , University Of Manchester , Embryology Association , University Of Texas Southwestern Medical Centre , Hull York Medical , Texas Southwestern Medical Centre , Professor Magdalena , Jurassic Park , Human Fertilisation , Synthetic Human Embryo Like Structures , தெற்கு ஆஸ்திரேலியா , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் , ஹல் யார்க் மருத்துவ பள்ளி ,

Advanced mouse embryos grown outside the uterus


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To observe how a tiny ball of identical cells on its way to becoming a mammalian embryo first attaches to an awaiting uterine wall and then develops into nervous system, heart, stomach and limbs: This has been a highly-sought grail in the field of embryonic development for nearly 100 years. Prof. Jacob Hanna of the Weizmann Institute of Science and his group have now accomplished this feat. The method they created for growing mouse embryos outside the womb during the initial stages after embryo implantation will give researchers an unprecedented tool for understanding the development program encoded in the genes, and it may provide detailed insight into birth and developmental defects as well as those involved in embryo implantation. The results of this research were published in ....

Chen Itzkovich , Valeriya Chugaeva , Ilana Mantoux , Itay Maza , Alejandro Aguilera Castrejon , Mirie Zerbib , Rada Massarwa , Jonathan Bayerl , Saifeng Cheng , Jacob Hanna , Muneef Ayyash , Shadi Tarazi , Tom Shani , Zvia Zeroni , Hadas Keren Shaul , Raanan Shlomo , Shahd Ashouokhi , Lior Lasman , Daoud Sheban , Yoseph Addadi , Noa Novershtern , Yonatan Stelzer , Bernardo Oldak , Nir Livnat , Sergey Viukov , Israel Cancer Research Fund ,

Advanced Mouse Embryos Grown Outside Uterus


Weizmann Institute of Science
To observe how a tiny ball of identical cells on its way to becoming a mammalian embryo first attaches to an awaiting uterine wall and then develops into nervous system, heart, stomach and limbs: This has been a highly-sought grail in the field of embryonic development for nearly 100 years. Prof. Jacob Hanna of the Weizmann Institute of Science and his group have now accomplished this feat. The method they created for growing mouse embryos outside the womb during the initial stages after embryo implantation until more advanced stages will give researchers an unprecedented tool for understanding the development program encoded in the genes, and it may provide detailed insight into birth and developmental defects as well as those involved in embryo implantation. The results of this research were published in Nature. ....

Chen Itzkovich , Valeriya Chugaeva , Itay Maza , Alejandro Aguilera Castrejon , Mirie Zerbib , Rada Massarwa , Jonathan Bayerl , Muneef Ayyash , Saifeng Cheng , Jacob Hanna , Tom Shani , Shadi Tarazi , Hadas Keren Shaul , Raanan Shlomo , Shahd Ashouokhi , Daoud Sheban , Lior Lasman , Yoseph Addadi , Yonatan Stelzer , Noa Novershtern , Bernardo Oldak , Nir Livnat , Sergey Viukov , Rambam Health Care Campus Of The Technion , Weizmann Institute Of Science , Rambam Medical Center ,