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Fecal transplant and fiber supplementation can benefit patients with obesity-related metabolic syndrome A transplant of healthy gut microbes followed by fiber supplements benefits patients with severe obesity and metabolic syndrome, according to University of Alberta clinical trial findings published today in Nature Medicine. Patients who were given a single-dose oral fecal microbial transplant followed by a daily fiber supplement were found to have better insulin sensitivity and higher levels of beneficial microbes in their gut at the end of the six-week trial. Improved insulin sensitivity allows the body to use glucose more effectively, reducing blood sugar. They were much more metabolically healthy, said principal investigator Karen Madsen, professor of medicine in the Faculty of Medicine & Dentistry and director of the Centre of Excellence for Gastrointestinal Inflammation and Immunity Research.

Karen madsenEmily hendersonUniversity of albertaCentre of excellenceChildren health research instituteWeston family foundationImmunity researchUniversity of alberta clinician investigator programCanadian institutes for health researchMicrobiome research coreGastrointestinal inflammationHealth research instituteAlberta clinician investigator programCanadian institutesகரேன் பைத்தியம்எமிலி ஹென்டர்சன்