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HR+/HER2- Breast Cancer: Inhibiting the PI3K/AKT/mTOR Pathway

Dr Vidal expands on use of PI3K/AKT/mTOR pathway inhibitors following frontline progression, focusing on the PI3K inhibitor alpelisib for patients with PIK3CA mutations, as well as capivasertib, an AKT inhibitor in development. ....

Aditya Bardia , Gregory Vidal , Komal Jhaveri , Hr Her2 Breast Cancer , Cdk4 6 Inhibitors , Second Line Therapies , Endocrine Therapy , Endocrine Resistance , Akt Inhibitors , Capitello 291 , Maintain Trial , Ember 3 , Oral Serds , Viktoria 1 ,