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KARDIA-2: Zilebesiran Drops BP on Top of Common Antihypertensives

Effects were more marked for patients already taking a diuretic or calcium channel blocker, but less so on top of a potent ARB. ....

United States , Akshay Desai , Wanpen Vongpatanasin , Md Ut Southwestern Medical Center , American Heart Association , American College Of Cardiology , American College , Medical Center ,

Novel Biannual Antihypertensive Shows Potential for Combination Therapy

Drug might be most effective with a diuretic, according to suggestive data from a phase II trial ....

University Of Louisville , United States , Akshay Desai , Pamela Bowe Morris , Nanette Wenger , American College Of Cardiology , University Of South Carolina , Emory University School Of Medicine , American College , Medical University , South Carolina , Emory University School ,

One Injection of Novel Drug Cuts Systolic Blood Pressure by Up to 12 mmHg

When added to standard blood pressure medication, new drug could minimize the need for pills and reduce cardiovascular risks ....

United States , Akshay Desai , Alnylam Pharmaceuticals , Us Centers For Disease , American College Of Cardiology Annual Scientific Session , American College , Annual Scientific , Disease Control ,

Study shows one injection of novel drug cuts systolic blood pressure by up to 12 mmHg

Study shows one injection of novel drug cuts systolic blood pressure by up to 12 mmHg
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United States , Akshay Desai , Us Centers For Disease , American College Of Cardiology Annual Scientific Session , American College , Annual Scientific , Disease Control ,

Study shows promise of zilebesiran injection in reducing systolic blood pressure

A single subcutaneous injection of the investigational drug zilebesiran, when added to existing treatment with a standard antihypertensive medication, reduced systolic blood pressure by between 4 to 12 mmHg on average at three months in patients whose blood pressure had remained uncontrolled despite compliance with their medication regimen, according to a study presented at the American College of Cardiology's Annual Scientific Session. ....

United States , Akshay Desai , American College Of Cardiology , Alnylam Pharmaceuticals , American College Of Cardiology Annual Scientific Session , Us Centers For Disease , American College , Annual Scientific , Disease Control , Blood Pressure , Blood Vessels , High Blood Pressure ,