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Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

In a new study, researchers pursued direct-acting severe acute respiratory syndrome coronavirus-2 drugs that compete for nucleotide-binding pockets (NBPs) of SARS-CoV-2 proteins. ....

Aimee Molineux , Neha Mathur , Neha Mathuroct , Nmps Ntps , Michal Bednarek Shutterstock , Protein Data Bank , Genomics Industry Focus , Image Credit , Brain Or Intestinal Estimated , Darglitazone Sodium , Coronavirus Disease Covid 19 , Ars Cov 2 , Ibonucleic Acid , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

The effect of ORF3c, a SARS-CoV-2 accessory protein, on cellular innate immune responses, autophagy, and lung cell mitochondrial metabolism

Researchers explored the role of the ORF3c, a SARS-CoV-2 accessory protein not so extensively studied as yet. ....

Genomics Industry Focus , Image Credit , Agilent Seahorse , Seahorse Mito Fuel Flex Test , Coronavirus Disease Covid 19 , Ars Cov 2 , Adenosine Triphosphate , Covid 19 , Fatty Acids , Hela Cells , Oxidative Stress , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

Study shows the important role of hepatocyte adenosine kinase in NAFLD progression

A study led by Texas A&M AgriLife Research provides compelling evidence of the important role of hepatocyte adenosine kinase in the progression of nonalcoholic fatty liver disease, NAFLD. ....

Bruxelles Capitale , United States , Chaodong Wu , James Cai , Chaidong Wu , Emily Henderson , Texasam Department Of Horticultural Sciences , Agrilife Research Faculty , Texasam Agrilife Research , Texasam Department Of Nutrition , Agrilife Research , Liver Inflammation , Agrilife Research Faculty Fellow , Presidential Impact Fellow , Veterinary Integrative , Horticultural Sciences , Fatty Liver , Liver Disease , Denosine Kinase , Protein Synthesis ,

Adenosine therapy can help with Coronavirus, Asthma and other respiratory problems, know details

Adenosine Therapy improved the quality of life of the patients by reducing asthma-related symptoms. It has also proven beneficial in helping ease coronavirus symptoms, and other respiratory problems like TB and lung cancer. ....

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Insights into molecular structure of protein assembly that plays key role in controlling cristae architecture

Energy supply is a vital component of economic life. And the complex interplay between society and economy is jeopardized whenever core services or key industrial sectors are at risk of failing because of energy supply problems. ....

Max Delbr , Emily Henderson , Saarland University , Professor Of Medical Biochemistry At Saarland University , Medical Biochemistry , Molecular Medicine , Mitochondrial Contact Site , Cristae Organizing System , Adenosine Triphosphate , Living Cells ,