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A new FDA-approved therapy for metastatic breast cancer

Now, the FDA has approved a treatment called Enhertu for metastatic HER2 low breast cancers that cannot be surgically removed. ....

Adam Brufsky , Drug Administration , Hillman Cancer Center , Cancer Center ,

Best Life: New drug treating triple negative breast cancer


Best Life: New drug treating triple negative breast cancer
Best Life: Treatment for tripe-negative breast cancer
By Ivanhoe Broadcast News | March 16, 2021 at 7:57 AM CDT - Updated March 16 at 6:17 PM
PITTSBURGH, Pa. (Ivanhoe Newswire)— About 15 percent of all women diagnosed with breast cancer have triple-negative breast cancer, meaning drugs that target estrogen, progesterone, and HER-2 protein—won’t work. In the past, if the cancer returned, patients have had very few options. More on a newly approved drug that is stopping the cancer in its tracks.
Jane Ellen Keenan is a cancer warrior, battling triple-negative breast cancer since 2013. She had six months of chemo, and surgery. The cancer was gone . for a time. ....

Jane Ellen Keenan , Adam Brufsky , Jane Ellen , Breast Cancer Center , Hillman Cancer Center , Ivanhoe Newswire , Ellen Keenan , Comprehensive Breast Cancer Center , Best Life , Breast Cancer Treatment , ஜேன் எல்லன் கீநெந் , ஜேன் எல்லன் , மார்பக புற்றுநோய் மையம் , ஹில்மேன் புற்றுநோய் மையம் , எல்லன் கீநெந் , விரிவான மார்பக புற்றுநோய் மையம் , சிறந்தது வாழ்க்கை , மார்பக புற்றுநோய் சிகிச்சை ,

Veru Reports Positive Phase 2 Clinical Trial Results for Enobosarm, Selective Androgen Receptor Targeting Agent, for Endocrine Resistant Metastatic Breast Cancer


Estrogen receptor (ER) is present in 85% of all breast cancers, and more than 90% of ER+ positive breast cancers also contain the AR which has been demonstrated to be an important therapeutic target in ER+ breast cancer. Enobosarm is an oral drug that selectively targets the AR in breast cancer without having the unwanted virilizing androgen adverse side effects including facial hair, acne, increase in hematocrit, or liver toxicity, while having potential clinical benefits including increasing muscle and physical function as well addressing cancer treatment induced bone loss and fractures. Enobosarm has extensive nonclinical and clinical experience having been evaluated in 25 separate clinical studies with 2,091 enrolled patients, including three Phase 2 clinical studies in advanced breast cancer. There are also at least two enobosarm investigator-initiated Phase 2 clinical studies in advanced breast cancer. ....

San Antonio , United States , Baylor University , United Kingdom , San Francisco , North Adelaide , South Australia , New South Wales , Dana Farber Cancer Institute , University Of California San Francisco , Mitchell Steiner , Patrick Cobb , Carlo Palmieri , Adam Brufsky , Beth Overmoyer , Joycea Oshaughnessy , Hannah Linden , Lees Schwartzberg , Charles Vogel , Stephen Birrell , Kirti Jain , Sam Fisch , University Of Washington Seattle Cancer Care Associates , Clatterbridge Cancer Centre , University Of Pittsburgh Medical Center , Wellend Health Burside Hospital ,