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Developing Bioactive Cell Culture Materials with Plasma Treatment

Developing Bioactive Cell Culture Materials with Plasma Treatment
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Van-vlasselaer
Stolwijkj-cytocompatibility
Sergeishimanovich-shutterstock
Acta-biomater
Harrick-plasmamay
High-energy-chem
Tissue-culture-plastic
Neuron-morphology
Smooth-muscle
Heart-valve-leaflets
Carbon-dioxide

CGRP sensory neurons promote tissue healing via neutrophils and macrophages

The immune system has a critical role in orchestrating tissue healing. As a result, regenerative strategies that control immune components have proved effective1,2. This is particularly relevant when immune dysregulation that results from conditions such as diabetes or advanced age impairs tissue healing following injury2,3. Nociceptive sensory neurons have a crucial role as immunoregulators and exert both protective and harmful effects depending on the context4–12. However, how neuro–immune interactions affect tissue repair and regeneration following acute injury is unclear. Here we show that ablation of the NaV1.8 nociceptor impairs skin wound repair and muscle regeneration after acute tissue injury. Nociceptor endings grow into injured skin and muscle tissues and signal to immune cells through the neuropeptide calcitonin gene-related peptide (CGRP) during the healing process. CGRP acts via receptor activity-modifying protein 1 (RAMP1) on neutrophils, monocytes a

Fiji
Acta-biomater
Talbot
Buckley
Wound-care
Trends-immunol
Trends-neurosci
Death-dis

Improving healthcare through the use of bioactive glass

In this article, Mo-Sci discusses how bioactive glasses can be utilized in order to advance healthcare, through avenues such as promoting bone growth or bone restoration.

Vietnam
Republic-of
Missouri
United-states
Finland
Acta-biomaterialia
Acta-biomater
Larry-hench
Alex-smith
Kokubot-woodhead
Steven-jung
Greenspand-bioglass

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