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Kidney Function Stable During 12 Months of Pegloticase-Methotrexate for Gout

Kidney Function Stable During 12 Months of Pegloticase-Methotrexate for Gout

Gout is a risk factor for CKD progression, so investigators probed the effect of pegloticase-methotrexate treatment on kidney function.

Trial results show gout therapy of pegloticase, methotrexate maintained eGFR vs placebo

AUSTIN, Texas —Results from a poster presentation here showed that patients with uncontrolled gout treated with the combined therapy of pegloticase and methotrexate saw a reduction in gout symptoms as well as a stable eGFR.Twelve-month data from the MIRROR trial showed a higher response rate among patients with chronic kidney disease when pegloticase (Krystexxa, Horizon Pharmaceuticals) was

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