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Trial results show gout therapy of pegloticase, methotrexate maintained eGFR vs. placebo

AUSTIN, Texas —Results from a poster presentation here showed that patients with uncontrolled gout treated with the combined therapy of pegloticase and methotrexate saw a reduction in gout symptoms as well as a stable eGFR.Twelve-month data from the MIRROR trial showed a higher response rate among patients with chronic kidney disease when pegloticase (Krystexxa, Horizon Pharmaceuticals) was ....

United States , Baylor College Of Medicine , Brad Marder , Gina Brockenbrough , Bymarke Neumann , Abdul Abdellatif , Horizon Pharmaceuticals , National Kidney Foundation Spring Clinical Meetings , Baylor College , National Kidney Foundation Spring Clinical , Healio Nephrology ,

Methotrexate Added to Pegloticase for Gout Safe for Kidneys

Methotrexate added to pegloticase for uncontrolled gout does not adversely affect kidney function, according to a randomized controlled trial. ....

United States , Baylor College Of Medicine , Abdul Abdellatif , American Society Of Nephrology Kidney Week , American Society , Kidney Week , Baylor College , Horizon Therapeutics ,