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Possible new PET tracer for early detection of Alzheimer s

Date Time Possible new PET tracer for early detection of Alzheimer’s New biomarkers for Alzheimer’s disease are a priority area for researchers seeking to learn more about the disease and find possible methods of early diagnosis. Researchers at Karolinska Institutet have now studied a new PET tracer that is an important diagnostic tool for the disease. The study on the tracer substance BU99008, which is published in Molecular Psychiatry, can play a key part in the early identification of signs of Alzheimer’s disease. The binding of the PET-tracer BU99008 shows reactive astrogliosis in different parts of the brain of a deceased patient with Alzheimer’s disease. The colours show the extent of the binding, where green is low, yellow is medium, and red is high binding. Credit: Amit Kumar.

More precise diagnoses made possible with whole genome sequencing

 E-Mail Credit: Stefan Zimmerman More than 1,200 people with rare diseases have received a diagnosis thanks to the integration of large-scale genomics into the Stockholm region s healthcare system. This is according to a study from Karolinska Institutet in Sweden that analysed the result of the first five years of collaboration on whole genome sequencing between Karolinska University Hospital and SciLifeLab. The work, published in Genome Medicine, constitutes a major leap forward in the emerging field of precision medicine. We ve established a way of working where hospital and university collaborate on sequencing each patients entire genome in order to find genetic explanations for different diseases, says the paper s first author Henrik Stranneheim, researcher at the Department of Molecular Medicine and Surgery, Karolinska Institutet. This is an example of how precision medicine can be used to make diagnoses and tailor treatments to individual patients.

More precise diagnoses made possible with whole genome sequencing

More precise diagnoses made possible with whole genome sequencing
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