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Molecular Partners AG: Molecular Partners Nominates Agnete Fredriksen for Election to Its Board of Directors ZURICH-SCHLIEREN, SWITZERLAND / ACCESSWIRE / March 11, 2021 / Molecular Partners AG (SIX:MOLN), a clinical-stage biotech company that is developing a new class of custom-built protein drugs known as DARPin ® therapeutics, today announced the nomination of Agnete Fredriksen, Ph.D., to the Company s Board of Directors proposed for election at the 2021 Annual General Meeting on April 21, 2021. We are pleased to propose Agnete for election to our Board of Directors during a time of growth and development for Molecular Partners, as we lay the foundations for an infectious diseases portfolio and new technologies for next-generation cancer immunotherapies to fruition, said Bill Burns, chairman of the Molecular Partners Board of Directors. We look forward to benefiting from her breadth of expertise across our deepening portfolio as we continue to expand th ....
Mar 11 2021 Read 205 Times Author: Robert P. Rambo on behalf of Diamond Light Source Ltd Free to read Unlock In 2020, the most significant application of Soft-condensed matter (SCM) science was, undoubtedly, the development of the COVID vaccines by Pfizer-BioNTech and Moderna which are composed of a synthetic messenger RNA encapsulated within a lipid nanoparticle [1]. SCM science drives continued improvements to quality of life as SCM science is integral to a broad range of industrial sectors. These sectors include food safety and waste, agriculture, polymers, coatings, additive manufacturing, lubricants and additives, personal care, electronics, energy storage, transportation, health and medicine. SCM materials occur over a range of physical states that include liquid, semi-solid, waxes, glasses and aerosols. This necessitates a complementary and diverse suite of instrumentation and methodologies for understanding how molecular de ....
Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma. ....
Researchers confirm new drug development route for treating multiple sclerosis, asthma Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma. The venomous toadfish Thalassophryne nattereri contains a peptide (TnP) with anti-inflammatory and anti-allergic potential. Confirmation of this potential has now come via the zebrafish Danio rerio, a popular aquarium species native to South Asia that shares 70% of its genome with humans and is widely used as a model for in vivo trials in drug development. The researchers tested TnP in D. rerio to measure its toxicity. In a little over a year, their research showed that the peptide is safe. It did not cause cardiac dysfunction or neurological problems in the toxicity tests they performed. ....
RNA editing events influence gene expression and phenotypic manifestation Combining computational mining of big data with experimental testing in the lab, researchers at Children s Hospital of Philadelphia (CHOP) have identified RNA editing events that influence gene expression and, in turn, the phenotypic manifestation of that expression. In analyzing so-called A-to-I RNA editing, in which the adenosine of an RNA molecule is chemically modified into an inosine, the researchers describe how a single nucleotide change by RNA editing can have large downstream effects. The findings were published today in Genome Biology. Millions of A-to-I RNA editing sites have been identified across the human transcriptome, but the functions of most RNA editing events are unknown. Understanding how RNA editing affects gene expression and phenotype could help us unravel the genetic basis to many human conditions. ....