Scientists test the effect of natural product isolated from sea sponge on cancer cells
Scientists from Far Eastern Federal University (FEFU) together with Russian and German colleagues, continue studying antitumor compounds synthesized based on bioactive molecules isolated from a sea sponge. One of them fights cancer cells resistant to standard chemotherapy, and at the same time has an interesting dual mechanism of action. A related article appears in
Marine Drugs.
Scientists have tested the biological effect of the marine alkaloid 3,10-dibromofascaplysin on various prostate cancer cells, including those resistant to standard docetaxel-based chemotherapy. The compound was first isolated from the sea sponge Fascaplysinopsis reticulata and subsequently chemically synthesized in FEFU. The substance forces tumor cells to die via a programmed cell death mechanism. This process is called apoptosis and is considered the most favorable mode of action of anticancer drugs.
Emerging protein-based immunotherapies could lead to highly effective cancer treatments
In a new commentary for the journal
Science, an associate vice president for research at The University of Texas at Arlington argues that emerging protein-based immunotherapies could lead to highly effective off-the-shelf cancer treatments for more patients.
Jon Weidanz, who also is a professor in the College of Nursing and Health Innovation at UTA, is the author of a perspective regarding the development of cancer immunotherapies.
His article, Targeting cancer with bispecific antibodies, will appear in the March 5 edition of
Science. It evaluates the findings of three studies by researchers at Johns Hopkins University and proposes that an emerging method of protein-based immunotherapy that targets commonly occurring mutations in cancer cells or neoantigens mutated antigens produced by tumor cells could lead to treatments that are effective for oncology patients.
The fallout of Winter Storm Uri prompted the Texas House of Representatives to convene its Energy Resources and State Affairs committees last Thursday and Friday in response to the crisis
During chromosome segregation, the dividing cell changes its shape so that two daughter cells are formed. This latter step is coordinated by the protein.
‘They can’t take away the word of God’: Trailer full of equipment stolen from church in Katy
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KATY, Texas – A Katy church is out tens of thousands of dollars after a trailer full of equipment was stolen. Band instruments, cameras, computers, and sentimental items, all gone.
Pastor Frank Hart says the thieves can keep the trailer. He just wants the stuff inside. They need it to run their Sunday church service.
“This is the kind of story God loves to tell, they meant it for harm but he’s going to use this for good,” Pastor Hart said.