What to Know About Using CBD for Migraines Anne Harding Replay Video Managing migraines If you get migraines, you've likely looked for all kinds of treatments to ease your headache pain. Along with pain medication, migraine home remedies, and lifestyle changes, you might have considered CBD for migraines. If you don't experience migraines, you likely know someone who does. Nearly one in four U.S. households includes someone who gets them, according to the Migraine Research Foundation. They are more than just headaches, and can cause debilitating head pain, along with nausea, vomiting, and extreme sensitivity to light and nose.