Unvaccinated holidaymakers will be BANNED from P&O Cruises' sailings Luke May For Mailonline Unvaccinated holidaymakers will be banned from P&O Cruises 'staycation' sailings this summer. Brits who wish to sail on a domestic cruise will have to have received both doses of the Covid vaccine at least seven days in advance of their trip, the UK's largest cruise line has said. Last week maritime minister Robert Courts told MPs last week that domestic cruises could be permitted from May 17. So far nearly 25million people have received at least their first dose of a vaccine, while 1.6m have received both.