hillary clinton. and here are the numbers-- a comfortable margin of victory for sanders after he narrowly lost in iowa. jace is likely to finish second among the republicans, leaving jeb bush, marco rubio, and ted cruz fighting for third. major garrett is in new hampshire and begins our coverage with the republicans, major. >> reporter: scott, donald trump won here tonight the way he has led in new hampshire almost from the very beginning, by pulling together different part of the republican party and serving as a galvanizing voice for their frustration with washington in general and specifically their own republican leaders inside the beltway. two pieces of exit poll data illustrate this sentiment very clearly. 40% of republicans said they are angry with the federal government in washington. 46% said they felt betrayed, betrayed by the republican now, trump in his victory won votes of establishment republicans, late deciders, conservatives, and moderates. and he stands as a leader, it appears, of a movement much more interested in backing a disruptive force in american politics than someone who could win the white house in november. the best example of that can be found in two other pieces of exit poll data, both dealing with the question of the most important characteristics. 29% of voters say they valued someone who could be an agent of change, 22% someone who tells it like it is. trump's achievement here stabilizes the campaign after the loss in iowa. it is worth pointing out, scott, that trump has, in south carolina, like he did here, held a sizable lead in the polls there for a good, long while. as for the rest of the republican field, john kasich, christie will have to wait a while longer for the final order to be determined and after that some campaigns will know if they can fight on and some campaigns will know it's time to give up. >> pelley: hillary clinton's campaign headquarters, she's expected there with a concession speech at any moment. bernie sanders has defeated her soundly. nancy cordes is covering the race for us. nancy. >> reporter: scott,"clinton struggled tonight with one of the constituencies she normally counts on, and that's women. eight years ago in 2008, women helped her come from behind to win here in new hampshire. she won among women by 12 point. but tonight, she trade sanders among women by seven point, and that was driven mainly by youngier women under the age of 45 who went for sanders by a 69% to 29%. younger voters in general went overwhelmingly for sanders, as they did in iowa. they are filling his watch party here in concord, new hampshire, tonight. but the clinton campaign anticipatedanticipated this loz so they put out a memo about an hour ago from their campaign manager and he said that her campaign is going to do better as it heads south, the states with larger african american communities, hispanic communities. clinton leads big among minorities and he argues, "that type of support has not created overnight. it was forged over more than 40 years of fighting for and alongside communities of color." so he is essentially defying sanders to try to make inroads quickly with those communities. he knows that sanders is heading straight to new york tomorrow to sit down for breakfast at the famed sylvia's restaurant in harlem with the reverend al sharpton. the sanders campaign argues that people of color learn more about his message of income inequality, and it won't hurt, scott, that he's going to be barreling out of new hampshire with a head full of steam after a big victory here, much bigger than the victory clinton can boast from iowa. >> pelley: nancy cordes thanks. so, what does all of this mean? we will turn to john dickerson our cbs news political director and anchor of "face the nation." john, what do you see in the republican race? >> reporter: well, one of the questions, scott, was whether donald trump could permanent when the voters had their say as well as he does in the polling. and that's whose happened here in new hampshire. and he's won not just with the very conservative but also with different other parts, the moderates. he's also taken hold of the policy debate here in new hampshire. 66% of new hampshire republicans yeah with his idea about banning muslim immigrants into the country. that's something no other republican would back him up on. another thing going on here that is marco rubio came in to new hampshire, came in third in iowa, was saying he's going to be the alternate toif trump and cruz. well, that's not the case anymore. it looks like john kasich is on the rise, maybe even jeb bush. so now the picture of an alternative to trump and cruz is quite muddled, and it's very difficult for marco rubio, who exceeded expectations in iowa, he's coming in under them here in new hampshire. >> pelley: and what about the democrats? >> reporter: well, another stunner for another outside candidate candidate. and bernie sanders trounced hillary clinton really across the board. the only groups that she did well with are very small ones, those who make over $200,000, those over 65, and nonwhite voters in new hampshire. the rest all goes to bernie sanders. and the big problem for hillary clinton is that if you look at those under 30, bernie sanders, that was 20% of the electorate, bernie sanders wins 85-14. so that's bad just for the primaries. but if hillary clinton thinks she's going to become the that coalition has younger voters as a central part of it. she's got to do better with those younger voters. but, of course, she's got to get through these future contests, first. >> pelley: joining us for his 11th new hampshire primary, the most experienced political reporter in television, bob schieffer. bob. >> reporter: you know, just to pick up on what john said there, i think hillary clinton needs to get to south carolina as fast as her feet will take her because that's the place eye know bernie sanders is going to meet with al sharpton tomorrow, but it's going to take a lot more than that. bill clinton, many people think, was the first black president, not barack obama. he going to be at every church, at every worship service across south carolina. i think it's going to be very, very difficult for bernie sanders from hereon in. i don't know where he get his support. and i think he's going to find that as these primariesses move across the south. donald trump now clearly in the driver's seat. i mean, he won in every group tonight, it seems, as i was looking across what we had there. some people will be surprised that john kasich is doing so well. i must say, i was not. i went to one of his town hall meetings, and he was really beginning to connect with voters. it's going to be hard for him once he gets to south carolina, especially because you're going to have the added thing of george w. bush is the most popular republican person down there right now. he also has lindsey graham on his side. this may be the place where if jeb bush is going to do anything, he's going to have to start doing it in south carolina. but right now, republican side of it, it was all donald trump tonight. >> pelley: bob schieffer, thank you very much, bob. and we'll be updating you with more results from new hampshire during prime time right here on >> pelley: a storm drops seven inches of snow. that's nothing new hampshire can't handle. another storm moving you want east coast made a mess in maryland today, flooding the big concern along the coast. high tide brought high water to the jersey shore. tonight, we also have a cbs news investigation into what is said to be a revolutionary blood test to detect cancer, even before a patient notices symptoms. several companies are racing to develop this. but are some promising more than they can deliver? jim axelrod and producer emily rand looked into this. >> reporter: at this health care conference in silicon valley a few weeks ago, biotech pioneers pitched the latest and greatest in personalized health care. >> this has the potential to totally change not just cancer, but all of medicine. >> reporter: dr. richard klausner is the former head of and a director of grail, a company developing a blood test for cancer known as a liquid biopsy somebody with no symptoms. >> no symptoms. >> reporter: could get their blood drawn. >> exactly. >> reporter: and you could determine they have cancer. >> that's the holy grail. >> reporter: the idea holds great promise, but klausner says proving it works will take time. clinical data yet and we have to get it. >> reporter: there is a lot of incentive. the liquid biopsy market isor expected to be worth $22 billion by 2020. another company after a piece ofo- it is san diego-based pathway genomics. pathway raised $40 million in its last round of fund-raising. >> it's, like, the most amazing thing. >> reporter: and raised its profile when one of its genetic tests was featured on "keeping up with the kardashians." >> mitch mulinex from pathwayro genomics. >> nice to see you. >> reporter: what caught the attention was the test pathway launched in september. >> introducing pathway genomics' intercept, detect and monitor. >> reporter: available by physician order for as little as $299, pathway's marketing claimed it could do what others say is years away. >> cancer intercept can detect a growing tumor in the body before the patient may notice symptoms. >> reporter: a few weeks ago, we visited pathway to ask them about their claims. before we sat down with the c.e.o., jim plante, they played us that marketing video. we just watched a video upstairs. >> right. >> reporter: and it says the liquid biopsy will detect cancer before symptoms. >> may, may. >> reporter: that's not what the video says. >> it says it may. we don't say "will." we say "may." >> reporter: you don't make the claim that you can detect cancer? >> uh, we say the informatione can be used to help guide potential early-- early diagnosis. >> reporter: we also asked plante about this chart showing the advantages of their liquid biopsy. >> we never say it replaces solid tissue biopsy. >> reporter: this chart looks like an either/or, jim, doesn't it? >> no, it's not an either/or. >> reporter: tumor biopsy versus cancer intercept liquid biopsy. >> it's an additional tool in the toolbox. it's one piece of information that helps guide the physician- patient discussion. >> while it's good to have extra tools, that doesn't mean we should be using them on our patient outside of research settings. >> reporter: dr. max dean is ags cancer researcher at stanford. pathway cites his research as evidence their test can detects cancer in otherwise healthy patients. >> i think we're still years away from that possibility. while we have -- >> reporter: years? >> years. that absolutely requires thousands of patients and long- term trials to prove that. >> reporter: thousands of patients, years of testing, millions of dollars. >> correct. >> reporter: and if a company isn't doing any of those three? order that test. >> reporter: the food and drug administration tells us it considers tests like cancer intercept a major health risk. in september, the f.d.a. sent pathway genomics a letter citing concerns the test did not have adequate clinical validation and l may harm the public health.te pathway now has three clinical trials under way to study its liquid biopsy, but it all began after the test was already on the market. and, scott, after our interview, pathway did pull that promotional data from its webs site. >> pelley: jim, thanks very much.rt. great report. you're probably wondering how these companies are able to sell unproven tests. well, jim will have more on that tomorrow on "cbs this morning." today, federal health officials sent hundreds of additional kits to florida to test for the zika virus. 16 cases are confirmed there, the most of any state. there are at least 64 cases indi 16 states and the district of zika is spread by mosquitoes and is suspected of causing a serious birth defect. will the rocket mortgage take off or is it a fast ride to trouble? the broncos get a parade fit forbr champions. and this little piggy goes to the polls when "the cbs evening news" continues on primary night._= hi hey you look good. thank you, i feel good. it all starts with eating right. that's why i eat amaz!n prunes now. i love these. sunsweet amaz!n prunes, the feel good fruit. if you're taking multiple medications, does your mouth often feel dry? a dry mouth can be a side effect of many medications. that's why there's biotene, available as an oral rinse, toothpaste, spray or gel. biotene can provide soothing relief and it helps keep your mouth healthy too. remember, while your medication is doing you good, a dry mouth isn't. biotene, for people who suffer from a dry mouth. >> pelley: mortgages to buyers who couldn't afford them put the u.s. on the road to the great recession. so we were curious when we saw an ad during the super bowl for an eight-minute mortgage. anthony mason went looking for answers. >> reporter: quicken loans super bowl ad made a simplee proposition: >> what if we did for mortgages what the internet did for buying music and plane tickets and shoes? >> reporter: that's what they're offering with rocket mortgages. >> you could get a mortgage onand your phone. >> reporter: but just seven years after the housing crisis nearly took down the economy, the ad rang alarm bells. of the "washington post" tweeted. >> i know that a lot of people interpreted the commercials of saying we're going back to the days of easy money but that'spl just simply not happening. >> reporter: holden lewis ofr: bankrate.com said the median credit score of a mortgage applicant is now 753 out of 850,f the highest since 2001. rocket mortgage is just trying to streamline the application process. is this quicken app a game changer, do you think? >> i think it's a game changer in a sense other mortgage companies are going to have to make it easier to put in your documentation and your paperwork. >> reporter: on the rocket app, you enter income and bank details, which allows quicken to communicate directly with banks. it estimates affordable home price and costs and allows customers to lock in a rate, says quicken president jay farner. fa >> if you go on to rocket mortgage, you can see the fees, and you can see how changing the interest rate would change your fees. >> reporter: so this is not about changing credit standards. >> no, quicken loans is known for having some of the highest credit standards in the country. >> reporter: rocket, he says, is trying to take the mystery out of the mortgage process. and that super bowl ad certainlyta got attention. farner says 14,000 people visited their web site in the first minute it aired, scott. >> pelley: anthony mason, anthony, thank you very much. the good times are rolling in new orleans. we'll visit when we come back. ibs-d. you know the symptoms when they start. abdominal pain. urgent diarrhea. now there's prescription xifaxan. xifaxan is a new ibs-d treatment and abdominal pain symptoms. and xifaxan works differently. it's a prescription antibiotic that acts mainly in the digestive tract. do not use xifaxan if you have a history of sensitivity to rifaximin, rifamycin antibiotic agents, or any components of xifaxan. tell your doctor right away if your diarrhea worsens while taking xifaxan, as this may be a sign of a serious or even fatal condition. tell your doctor if you have liver disease or are taking other medications, because these may increase the amount of xifaxan in your body. tell your doctor if you are pregnant, plan on becoming pregnant, or are nursing. the most common side effects are nausea and an increase in liver enzymes. if you think you have ibs with diarrhea, talk to your doctor about new xifaxan. don't let a cracked windshield ruin your plans. trust safelite. with safelite's exclusive "on my way text" you'll know exactly when we'll be there. giving you more time for what matters most. speaking, breathing, eye problems, or muscle weakness can be a sign of a life-threatening condition. side effects may include allergic reactions, neck and injection site pain, fatigue and headache. don't take botox if you have a skin infection. tell your doctor about your medical history, muscle or nerve conditions, and medications, including botulinum toxins, as these may increase the risk of serious side effects. put the odds on your side. visit botoxchronicmigraine.com to learn how to save on your treatment. talk to a headache specialist today about botox . i tried depend last weekend. it really made the difference between a morning around the house and getting a little exercise. only depend underwear has new confidence core technology for fast absorption and the smooth, comfortable fit of fit-flex protection. get a coupon at depend.com >> pelley: we're back now with the latest vote totals coming in democrats first. sanders. cbs news estimates he will be the winner with about a third of the vote actually counted. he's way ahead, 56% to 40%. hillary clinton gave a concession speech in new hampshire just a few minutes ago. >> i still love new hampshire and i always will. ( cheers and applause ) and here's what we're gonna do. now we take this campaign to the entire country. we are going to fight for every vote in every state. we're going to fight for real solutions that make a real difference in people's lives. >> pelley: now, let's look at the republican side of the race. these are the very latest vote totals coming in. donald trump far ahead, double his nearest competitor, john ted cruz, jeb bush, marco rubio trailing. a big fight now for who will come in third in the republican race. but a broad win for donald trump across just about every demographic in that state. we'll be back in just a moment. >>this portion of "the cbs evening news" is sponsored by pacific life. for life insurance, annuities and investments, choose pacific life. the power to help you succeed. for more than 145 years, pacific life has been providing solutions to help individuals like you achieve long-term financial security. bring your vision for the future to life with pacific life. talk to a financial advisor to help build and protect your retirement income. pacific life. (toilet flush) if you need an opioid to manage your chronic pain, you may be sooo constipated it feels like everyone can go ...except you. tried many things? still struggling to find relief? you may have opioid-induced constipation, oic. opioids block pain signals, but can also block activity in the bowel. which is why it can feel like your opioid pain med is slowing your insides to a crawl. longing for a change? have the conversation with your doctor about oic, and ask about prescription treatment options. made on behalf of those living with chronic pain and struggling with oic. northern nevada is getting ready to caucuss... caucus training is going on right now... a live report, >> >> pelley: as the candidatest await the vote count tonight, we size up the competition. not theirs, ours. here's julianna goldman. >> reporter: you might think this is any other shoe leather reporter covering hillary ham clinton in new hampshire, butly kaitlyn clark is just 11 years >> is there any specific issuesal you really want covered? >> reporter: she's among the 20 on assignment for "scholastic news" providing a kids'-eye view of the political process. >> we're going to get a lot more good jobs with rising incomes for people. >> thank you, and do you have a plan so you know how to do that? >> i do, i do. >> reporter: 14-year-old gabe ferris has learned sometimes you score interviews. >> why should young voters vote for you, trump? >> because your future is much better with me than anybody else. >> reporter: and like the rest of us, sometimes you don't. >> governor kasich, why should young voters vote for you?at that's just the nature of the beast. you're not going to get every interview, i guess, so on to the next candidate. >> reporter: and anyway, gabe's colleague, maxwell surprenant,it had already spoken with john kasich, and filed a blog post. >> there are a lot of issues that affect kids it's environment, education, the economy. that's one of the reasons ion i get to tell other kids about that. >> reporter: scholastic has had a volunteer press corps since 2000. since then, the job has evolved. they're juggling the multitasking demands of campaign coverage, shooting videos, taking notes on iphones, and, of course, tending to their twitter feeds. as for making political predictions, kaitlyn has seen enough of this cycle not to.ev >> i think it's just a level playing field right now, and we'll find out tuesday night. >> reporter: cub reporters making civics class look like child's play. julianna goldman, cbs news, washington. >> pelley: there's no democracy without journalism. that's the cbs evening news for tonight. we'll be watching the voting in new hampshire and bring you updates throughout the evening. for all of us at cbs news all around the world, we'll see you again soon. at wgbh access.wgbh.org "this is channel 2 news, coverage you can count on" garth "we're making good progress now that the weather has cleared up here for the past few days." after years of planning and litigation -- construction of the southeast connector is moving full-speed ahead. an update on the project as the cone zone tops channel 2 news at 6:30. work on phase two of the project got underway last summer -- and it appears that there are no obstacles in site, now that all of the proper permits are in place. good evening -- i'm landon miller. and i'm kristen remington. thank you for staying with us tonight. a lawsuit that aimed to stop construction was also dropped back in november. the southeast connector will extend veterans parkway in south reno -- stretching 5-and-a-half miles from south meadows parkway to greg street. paul nelson joins us at the construction site on pembroke drive. paul -- how is the project going so far. with the progress, kristen.

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