Cannabidiol or cbd. Well, now its part of our daily dialogue and its ignited a multibilliondollar trindustry. And that got us wondering has it gone too far . So were back on the road across the United States and the world searching for the truth about cbd. From oils from tinktures to lotions to lattes. We sell pretty much everything, you name it. In every shape and size for pain, for anxiety, even soft skin. This says its for. Hangover. Cbd is everywhere. Its even in the water. Its in coffee as you walk down the streets. You see cbd signs everywhere. We know it wont get you high. But we still dont know much more. Research is slim. Hey, sweetheart. Yet Success Stories are not. She was dying. She was not going to live long. Lives changed for the best. But now we are also learning about lives that were changed for the worst. Experts are warning about a spice product that i being sold at local smoke shops. The concerned centers around cbd oil. You thought you might die . Honestly, yeah. What you thought was harmless could be dangerous. Is the cbd supply chain safe . And whats legal could be illegal. What you need to know. We wanted to make sure you knew. This is weed 5 the cbd craze. As im driving down these colorado roads, i realize that we should start this journey right where our first weed investigation began, back in 2013 with this family of pioneers, a band of brothers who many think are responsible for starting the cbd craze. These are the Stanley Brothers. Whats going on, brothers . When we first introduced you to them back in 2013. Im joel. Im josh. They were young, unknown, and struggling with a new business. Now everywhere you guys go theres cameras chasing you. Now june 2019, theyre a bit older, more experienced, and very rich. Their cbdbased Cannabis Company is now a marijuana empire. Publicly traded and worth an estimated 2 billion. Has it affected you . We are able to drive cars now that will actually get to where were going. [ laughter ] thats true. Back then, they were growing 600 pounds of medical marijuana a year on less than an acre. Greenhouse one. Wow. Betting the farm on thc. And on the side experimenting with something few had considered. Theres nothing like this in the world. This plants 21 cbd and less than 1 thc. Initially, many wondered who would want a strain of marijuana that doesnt get you high . Remember, cbd is the nonpsychoactive part of the plant. But josh and his brothers knew even then that this had potential. This area, without putting it lightly, is the future of medical marijuana. Something the world would soon learn from a little girl named charlotte. She has been called patient zero for the cbd craze. The most important thing ill have ever do is help my child and share that information to help others. Born with a rare form of epilepsy, charlotte had a sezure every 30 minutes. Every one potentially fatal. When nothing helped. This is charlottes web. Her parents gave charlotte the stanley cbd oil. She didnt have a seizure that day. And then she didnt have one the next day. Then the next day. I just thought this is insane. That was six years ago. That i think really catapulted cbd into the National Limelight as the most favored cannabinoid. Cannabis research dr. Donald abrams believes thats when the cbd craze began. It was sort of under the table until charlotte and sanjay gupta got together and threw it into the public domain. The stanleys and their special cbd strain became famous. They have been contacted by thousands of families. All of a sudden everyone wanted the thing that had helped that little girl. Jared stanley and his brothers cant grow the plants fast enough. And that third of an acre that i walked on more than six years ago has been replaced. Now its almost 800 acres. This has got to be one of the Fastest Growing things that i think ive seen, i mean, in any kind of industry. My poor brother jared who runs the entire agricultural division, he hasnt slept in seven years. As the stanleys empire grew, so did the countrys interest in cbd. A recent poll shows that two out of three americans now know what cbd is. And one out of seven use it. Im here in downtown new york city which is like a lot of cities around the county. There are a ton of stores here selling cbd products. So im going to talk to somebody whos been following the cbd craze very closely. Hey, lisa. Hey, how are you . Nice to see you. Thanks for making some time. Lisa gill is an Investigative Reporter for Consumer Reports. Thats the bible for mainstream consumer products, an unexpected place to read about cbd. There are thousands upon thousands of products across the United States on store shelves and not even counting whats online. Mints, lotions, oils, bath balms, gummies, popcorn. What is this . Even it looks like a joint. And it smells like marijuana. I mean i feel like i would totally get busted. I think i would too. I swear, officer, its cbd. Its totally. All kidding aside, this is where it gets a little confusing. For decades, cannabis including cbd has been illegal federally. That all seemed to change with the passage of the 2018 farm bill which technically made growing hemp with cbd in less than. 3 thc legal. Or at least thats what most people think. Even though it makes cbd federally legal, it allows the states to decide whether or not they are going to permit sales of it or permit farmers to grow it. So, in my opinion, its very confusing for an individual to try to understand, well, what is my state doing . Whats even crazier is that lots of retailers sell it anyway. So you might walk into a store and think it must be legal because its here. In my personal 15 years of covering pharmaceutical medications, overthecounter medications and supplements, there is not one compound like cbd. Yet despite the confusion, people and companies are willing to take the chance. Theres so much money to be made. The u. S. Cbd market hit an estimated 591 million in 2018. And experts believe they could hit 22 billion by 2022. All because of those seven brothers. And that one little girl. But with success comes new concerns. Any time a craze comes out, you have everybody trying to jump in the boat, that can be a little bit dangerous. That side of the story when we come back. Applebees new pasta and grill combos. Choose from up to 12 combinations starting at 9. 99. Tmobiles newest signal reaches farther than ever before. With more engineers. More towers. More coverage its a network that gives you freedom from big cities, to small towns, were with you. Because life can take you almost anywhere, tmobile is with you. No signal goes farther or is more reliable in keeping you connected. My bladder leak underwear. Orried someone might see so, i switched. To always discreet boutique. 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This is not a bed its proven quality sleep. From 999. I work hard and i want my money to work hard too. So i use my freedom unlimited card. Even when im spending, im earning 1. 5 cash back on everything i buy. Earning on my favorite soup. Got it. Earning on that eclair. Dont touch it. Dont touch it yet. Let me get the big one. Nope. This one . Nope. This one . No. Let me get them all. Im gonna get them all. Its just the basics. Can you double bag this right here . Earn 1. 5 cash back on everything you buy with freedom unlimited. Can you also tell me what it is . Chase. Make more of whats yours. This has been like two months now. Is it very welldocumented . Had. These are complicated issues. Cbd did seem so simple then. It was 2014 when we first started covering the case of vivian wilson, a new jersey toddler with seizure just like charlotte. Please dont let my daughter die, governor. Her father wanted some of charlottes oil to help his daughter to save her life. Its a horrible thing to have to see your daughter suffer like this. After losing the fight to access cbd because of then governor Chris Christies medical marijuana laws. It will not happen on my watch ever. The family moved to colorado. Come on in. To legally access the cbd oil the stanleys had used with charlotte, now called charlottes web. We were there in their new house for vivians first dose. 2014. We came out here for cbd and you want to believe that its going to be the cure. Is this her . Yes. Im excited to see her. 2019 when we arrived back in denver to see the wilsons again we quickly learned that vivian had tried many different kinds of cbd, and none of them had been a cure. How are you . We moved twothirds of the way across the country for cbd which is like something that you can buy in your butter now. Is it all good . I dont think so. I think theres a lot of misinformation. Whatcha doing here . Turns out vivians experience with what seemed to work miracles for some was not miraculous for her. We saw this like initial improvement and things were good. The more we were increasing her cbd, the more seizures she started having at night up to like 40 a night. And we just couldnt figure out what it was. Theres no evidence that cbd caused these seizures, but clearly it was no longer working for her. It wasnt the benefit that they were necessarily seeking. Dr. Kelly, vivians neurologist from Childrens Hospital in denver remembers those early years for the wilsons. When a new medicine is started, we may see benefit for a couple of months, sometimes six months, 12 months, and then the benefit may gradually go away, and we dont fully understand why that is. One day i just looked at brian and i said, like, you know, she just seized all night long. I said its the cbd, im done. We stopped and she never had another focal seizure again in her sleep. It was the exact opposite of what we found just 60 miles away. When we arrived at the figges doorstep. Sanjay welcome back. Hey, charlotte. Hey, sweetheart. Do you remember me . [ laughter ] i think thats a yes, maybe. It was more than we expected, and it was more than paige had ever allowed herself to hope for. Youre walking pretty good, sweetheart. I cant imagine back then seeing her at 12 years old and what that would look like. She was dying. She was not going to live long. How is charlotte doing . Shes good. Shes stable and she doesnt take any medications, just this oil that shes been using for more than half of her life. But why did cbd work so well for charlotte . But not for vivian . What is different about the children who responded to cbd from those who didnt . So im wondering if there is some honeymoon effect there as well. There is a suspicion that maybe it works by increasing the blood level of the antiseizure medicine that the children were already on. Some think this honeymoon period that kids like vivian experienced might be explained by her liver. Cbd works in the liver, in the enzymes that break down the other prescription medicines. And cbd inhibits those enzymes so that they dont break down pharmaceuticals to the extent that they should be broken down, allowing them to get a higher level. And perhaps more effective or perhaps more toxic. The fact that cbd can affect your liver enzymes and change the way drugs interact with your body could potentially be very dangerous. 60 of medications are broken down in the liver that could be anktded by cbd use. They include drugs you might use every day, antibiotics, antihistamines, antidepressants. Its not entirely benign. And thats one of my concerns about the widespread use of cbd. Thats medicine in that bag . Thats what i think, trying to prove it. When i first met Donald Abrams four years ago he was on the cutting edge of cannabis research. So much promise then, but he says not much progress now. He does still believe in the potential healing power of marijuana but is concerned about cbd alone. The cbd craze that were in i think is unprecedented really in the history of medicine. Its a compound that has gotten way ahead of any research to support the claims that are being made. Abrams was part of the team of doctors in 2017 with the National Academy of sciences that did what is considered the most comprehensive review of all the studies done on the benefits of cannabis. There are only about five in the medical literature studies looking at the therapeutic benefits of cbd. Not only are there few studies, the studies that we have are not very good quality. And theres hardly any research at all for the benefits of all those wellness products in stores. Theres very little for a lot of these things. But the potential side effect, particularly for low doses, episodically is pretty low. Might help, cant hurt. Why not . 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In life everyone has days they wish they could just forget. For College Junior jay jenkins, that day was may 8th, 2018. Youre sitting there in the passenger seat just like you are now. Right, just like i am now. My buddy asks if id ever tried cbd oil. So i said no, im not really interested in it. Why would i . And he asked a few more times, and eventually i gave in and said sure, you know, ill try it. They drove to a Convenience Store and bought a cbd product labeled yolo. Yolo stands for you only live once. Why did you do it . I didnt think there was any risk in trying it. I had never heard about anybody having any negative effects from it. So i thought that i had nothing to lose. I took two puffs off of it, the next thing i know, im feeling crazy and not thinking straight, not being able to move. Within seconds jay appeared to have lost consciousness and started to have frightening hallucinations. His friend drove him to Lexington Medical Center where he started having seizures. They said that i scored a 3. So 15 is basically normal and three is braindead essentially. Yes, sir. You thought you might die . Honestly, yeah. At the time i was seeing all this crazy stuff going on in my head, all these crazy hallucinations going on. I thought that i was in hell and that i was already dead. What did the doctors say to you . They said that if i had gotten there much later then i wouldnt have been able to survive. He recovered physically from the trauma of it all. But make no mistake. He is still suffering mentally and asking lots of questions. What was in the cbd . What got him so sick . Isnt cbd supposed to be safe . What jay would soon learn is that around the same time, people 2,000 miles away in salt lake city, utah, had also been getting sick from a similar substance. Experts are warning about a spice product that is being sold at local smoke shops that concerns products labeled cbd oil. People started calling utahs Poison Control Center and showing up in the Emergency Rooms saying they had used a liquid cbd oil. Barbara, executive director of poison control, remembers that very first call. One of our specialists said to me, you know what, this is really odd. I have this case, they called me about it and sort of describe that this was supposedly cbd they had vaped. As more calls came in crouch knew something was wrong. It is the nonpsychoactive component of the cannabis plant. So the first thing we said is this is not consistent with cbd. I contacted the Health Department and said somethings going on here. I dont know what it is, this doesnt make sense, but something is going on. Everything pointed to the one thing most patients had in common. They had used a counterfeit product labeled yolo, cbd oil, similar to the one jay took. So crouch went to a local smoke shop to obtain an unopened bottle for the police. That gentleman showed me the product, and he asked me what my tolerance for getting high was. It was clear to me that the overall intent was not necessarily therapeutic. Is this product in the bottle something thats from an accredited laboratory or is it something thats made in somebodys garage . Agent christopher with the state bureau of investigation was assign