container that can be used to keep it cold enough for up to ten days at a time. but even then there are incredibly strict regulations. you can only open it for up to a minute ata time can only open it for up to a minute at a time twice a day without ruining the temperature and therefore potentially invalidating therefore potentially invalidating the effectiveness of the vaccine inside. i think we've got a real task on our hands of working out the logistics. that will of course be far harderfor partner logistics. that will of course be far harder for partner countries and of course the developing world. the guardian main story for them vaccine programme ahead of programme by christmas. we cannot let our enthusiasm run away with those portions of sense. below that the situation in wales. optimism after a 17 day fire break there. i don't know about you, i didn't think the numbers could drop by that much. they have a drop by that much yet. i think it's fair to say the jury is still out. there are people in wales, chief medical officer in wales, chief medical officer in wales saying they are cearley annexing early signs i think starting to improve. as ever with this virus there is a big lag between doing something and then actually saying that start to come through in the numbers. it always takes a few weeks. i think it's probably too early to tell wales is an interesting experiment because it did what borisjohnson an interesting experiment because it did what boris johnson chose an interesting experiment because it did what borisjohnson chose not an interesting experiment because it did what boris johnson chose not to do, it went with that circuit breaker, fire break whatever you wa nt breaker, fire break whatever you want to call it. brief lockdown earlier in the roll—out of the second wave of the virus. and we wait to see how effective that was. if it does turn out to be effective doesn't turn out to have the same effects of this then boris johnson's not going to look very popular on the back of that, is he? i think it's too early to say. probably another couple of weeks will know for sure. what do you make of this lucy? the figures were going into the circuit breaker the numbers were 250 per 100,000 cases in terms of infection rate and that is now dropped by only 30 to 220 per 100,000. that's right. as jack says, we need to look at how it looks in a couple of weeks' time. an important thing is the direction at which the infection rate is going. that's why scientists have always said even when it looks like it's increasing above the our rate above one even just a tiny bit, that will still proliferate pretty quickly for some again, it can potentially go down quite quickly. i think we will have to wait and see. it proves that it does work, has at least some degree of effectiveness and i think that is a really important principle to prove. looking at the ft, the other big shot in the arm is come from the financial market off the backs of this vaccine announcement. a lot of sector is doing extremely well today. it's good news all around, is in a? they've gone absolutely through the roof. especially those that have been hit so hard. i noticed airline shares in particular going absolutely nuts at lunchtime. that's because suddenly people are thinking hang on, i've got a chance at probably going on a holiday next summer i'iow. at probably going on a holiday next summer now. and the airline is recovering all those billions they lost. exactly. and energy company similarly. they've been hit very ha rd by similarly. they've been hit very hard by the pandemic. their stocks are going up and up most actors have takena big are going up and up most actors have taken a big boost today. the ones you mentioned that hasn't is the tech sector which is done so well at the pandemic. so many people working at home. they are the ones that seem to be taking a hit today for some ice on zoom shares the video conferencing platform down 12 to 15% at one point. seems a bit harsh to me. i feel that working from home and those sorts of thing, i feel like they are here to stay now. even if this vaccine proves is good is it hopes and life does seem to return to normal next year i think there are a lot of things, that we will not be going back to. lucy, do you spare a thought for president sharp of the white house? he's been tweeting furiously about this today. and indeed donald trumpjunior has been raising sceptical questions about the timing of this, as well. it's what we've come to expect from the terms, is it a? i've been interested in joe biden the terms, is it a? i've been interested injoe biden making his first major speech on coronavirus today. quite stark that while donald trump has been hitting golf balls in the recent days he's already been setting up a coronavirus task force. trying to position himself as the president in waiting as we now know he is the president—elect. interesting difference in the responses stateside. final thought from you jack, one of the people on the joe from you jack, one of the people on thejoe biden task from you jack, one of the people on the joe biden task force from you jack, one of the people on thejoe biden task force is the whistle—blower against the trump plans for dealing with a coronavirus. pandemic. ithink second only to the discovery of a vaccine in terms of a shot in the arm and the fight against covid is the election ofjoe biden. a guy who is going to take this pandemic seriously. in a way that donald trump simply never has. he's going to reverse the decision to pull out of the who. he's already starting to think about how we can tackle this creatively. and hopefully were going to see the leadership from the united states that we would've expected so many years gone by when there isjust expected so many years gone by when there is just been expected so many years gone by when there isjust been sadly dismally lacking under donald trump. yeah, joe biden pointing out today in that speech are well maintained that the worst is yet to come potentially for the american population. we will stop now. but we are going to see you in about a0 minutes' time for another look at the papers. and to see how many other papers got different takes on this pfizer vaccination. thank you very much indeed. good evening... i'm gavin ramjaun and this is your latest sports news. we'll start with the first round of the fa cup where oxford city have beaten northampton town, to book their place in the second round. it's yet another giant killing, after a weekend where several english football league sides have been beaten by non—league opposition. oxford city are in the national league south, three tiers below league one northampton, who were well short of the pace. oxford's reward is a second round tie against shrewsbury. chorley‘s reward for knocking out wigan on sunday is a second round tie against peterborough. they'll travel to london road to face the highest ranked team in this stage of the competition and all the other fixtures are on the bbc sport website. sheffield wednesday have sacked their manager garry monk. monk had been in charge of the championship team forjust over a year. the owls had just climbed off the bottom of the table last weekend, after a points deduction for breaking efl rules was halved from 12 points to six on appeal. saturday's goalless draw with millwall at hillsborough proved to be monk's last game in charge of the club. footballer megan rapinoe is certainly no stranger to success on the field. and off it she reamins one of the most influential voices in sport. even offering to becomejoe biden's running mate in the lead up the america presidential election. as part of bbc sport's women in football week, jo currie has been speaking to her. it's rapinoe! it's brilliant. she is a two—time world cup winner, an olympic gold medallist and was voted the best player in the world last year. but megan rapinoe's reputation goes beyond the football field. she's not shy of using her platform give others a voice. to give others a voice. in her new autobiography, she talks about speaking to president—elect of the united statesjoe biden on the phone. and she is a big fan of his incoming vice president kamala harris too. we need to put more women of colour in power. we need more womenjust in general in power. we need to diversify the way that our government looks. i mean, if you put a whole roster, you know, there's one little section of women and gays and black people. and it's just not enough. her willingness to stand up for others has sometimes come at a cost. in 2016, rapinoe became the first white american athlete to kneel during the national anthem in solidarity with nfl star colin kaepernick who was highlighting racial inequality and police brutality. us soccer subsequently banned their players from making the protest and rapinoe says she felt frozen out from playing for the national team. i'm proud of speaking my mind and doing the right thing. i think we can all agree that four years later everybody‘s kneeling now, you know, everybody‘s kind of down with it. usa soccer put out a statement rescinding the rule that you have to kneel and, you know, effectively an apology that the stance they took was wrong then and it's wrong now. five of rapinoe's us world cup winning team mates have come to play their football in england this season. so, what would it take for her to make the move to the women's super league? i like the idea of it. but it's just such a life change at this point. you know, being 35, i mean, just being really honest it would take a lot of money. money that frankly i'm not worth as a soccer player. under donald trump, rapinoe once refused to visit the white house. but with a shift in power she is now happy at home in but with a shift in power she is now happier at home in america but says she and other athletes have a responsibility to keep fighting to give others a voice. jo currie, bbc news. to tonight's action in the pro 1a, where ulster remain unbeaten in the league with a a0 points to 15 win over glasgow warriors. a straightforward victory in conference a at the kingspan stadium — ulster scrum—half john cooney kicked ten points as well as scoring this try, one of six from ulster on the night. meanwhile in the night's other game at murrayfield. edinburgh overcame both the fog and cardiff blues to take their second win of the season by 15 points to 0 — ——18 visibility almost impossible in the second half as the scottish side ended a four—game home losing streak. to rugby league — and challenge cup runners—up salford are looking for a new coach after announcing the sudden departure of ian watson. the red devils say watson, who has been at the club since 201a, has left them with immediate effect after being approached by another super league club. the news comes just a fortnight after he rejected an approach from hull and pledged to see out his salford contract, which was due to run to the end of 2022. former champion sergio garcia will miss this week's masters after testing positive for covid—19. tournament officials announced the news on social media on monday afternoon, just three days before the tournament gets under way. garcia defeated justin rose in a play—off to win his first major title at augusta in 2017. players like to get to the masters as early as possible. it is a very, very special place for golfers. so i would imagine that the vast majority of the field will have gone through the preliminary testing procedures. and if sergio garcia is the only positive test then that's potentially very good news for the rest of the field. these are unique circumstances, it is going to be eight masters like no other. england's jonny bairstow has signed for big bash side melbourne stars. bairstow has been recently playing in the indian premier league and will be available to play for the stars after christmas. and that's all the sport for now. hello again. we've got some more murky weather with us at the moment, particularly across eastern scotland, with some dense fog patches, visibility down to 100 metres, some fog through the central belt and some fog as well across north east england. now, further southwards, we've got these bands of rain moving in across england and wales. that's down to an area of low pressure. and some of this rain is washing the fog out of the atmosphere, so it's still a little bit murky. there's some mist patches around, but it's not as foggy as it has been. the worst of the dense fog, as i say, is further north—east, for eastern scotland, through the central belt and into parts of north east england as well. through the central belt and into it will be a mild start, though, to tuesday. temperatures for many of us in double figures, 10—11 degrees early in the morning. and through the morning, there will be cloud and there will be some patchy outbreaks of rain around as well. the fog will lift into low cloud across the north east before thinning. and i'm pretty optimistic, actually, many of us will have some brighter weather through the afternoon, with a little bit of sunshine poking through the clouds. temperatures on the mild side, hights between 13—15 degrees. this is bbc news with the latest headlines for viewers in the uk and around the world. is this the breakthrough? us pharmaceutical giant, pfizer, says, it has a coronavirus vaccine that's more than 90% effective i've never felt professionally such a moment ofjoy, and we werejustjumping up and down in the chairs ofjoy for humanity, joy for medical advances to put an end to this dreadful pandemic. it comes as the us passes more than 10 million cases. joe biden sets up a special task force — and this is his message on face coverings. a mask is not a political statement.