Three Of The Best Margaritas In South Dakota Are In Sioux Falls Even though Cinco De Mayo has passed, that doesn't mean you still can't celebrate! Any time is a good time to enjoy a magnificent margarita! Whether you're going to a bar or Mexican restaurant in Sioux Falls or anywhere in the Sioux Empire, it’s always a fun night when margaritas are part of the mix. There are many great local restaurant options to choose from to enjoy margaritas. The only question is where do you go? Well, you're in luck! There's a brand new list that identifies the best spots to get a margarita in South Dakota!