For some years now, the trend in the cosmetics and skincare sector has been toward transparency and natural, sustainable ingredients. A growing number of consumers are rejecting cosmetics that contain petroleum-derived mineral oils and silicone oils. As a result, manufacturers are increasingly turning toward plant-based oils, fats, and waxes as substitutes. Working in tandem with Kneipp GmbH, a well-known producer of cosmetic products and other items, the Fraunhofer Translational Center for Regenerative Therapies TLC-RT at the Fraunhofer Institute for Silicate Research ISC is conducting the first-ever systematic tests of the general protective and regenerative effects of plant oils on the skin. The researchers are using a 3D skin model cultured in vitro for their work.