Study opens a window of opportunity to design RAF1 degraders

Study opens a window of opportunity to design RAF1 degraders against lung adenocarcinomas

One of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes -genes that cause cancer when mutated - are responsible for a quarter of all human cancers, including the three tumor types with the highest mortality rates: lung adenocarcinoma, colorectal carcinoma and pancreatic ductal adenocarcinoma.

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Copenhagen , Køavn , Denmark , Pablo Mesa , Mariano Barbacid , Sara Garc , Emily Henderson , University Of Copenhagen , Molecular Cell , Structural Biology , Cancer , Drugs , Protein , Adenocarcinoma , Arcinoma , Fell , Olorectal , Genes , Ortality , Ncology , Research , Humor ,

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