This study is led by Prof. Xishan Wang (Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College), Prof. Chuangang Fu (Shanghai East Hospital, Tongji University School of Medicine), Dr. Xu Guan (Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College), Dr. Xiyue Hu (Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College) and Prof. Zheng Jiang (Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College), on behalf of China NOSES Alliance.