Mar 15, 2021 - 3:22 PM ET You’ve got to love the clear mistakes in seeding by the NCAA Tournament committee, just like in the Midwest Region’s 10 vs. 7 matchup. The 10-seed Rutgers Scarlet Knights are actually slight 1-point favorites going up against the 7-seed Clemson Tigers. This is a matchup of two very strong defensive teams who have survived through roller-coaster seasons, but who has what it takes to extend their March Madness stay and cover the small spread? Find out in our best Rutgers vs. Clemson March Madness picks and predictions for college basketball betting action on Friday, March 19. Rutgers vs Clemson odds