Personalized Neoantigen Vaccine Induces Continued Responses

Intradermal injection with GNOS-PV02 plus plasmid-encoded interleukin-12 followed by electroporation elicited complete molecular response detected via circulating tumor DNA in 4 additional patients as second-line therapy in patients with advanced hepatocellular carcinoma.

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New Zealand , Auckland , Barcelona , Comunidad Autonoma De Cataluna , Spain , Niranjan Sardesai , Ted Gane , University Of Auckland , New Zealand Liver Unit , Auckland City Hospital , Barcelona Clinic Liver Cancer , Gnos Pv02 Plus Plasmid Encoded Interleukin 12 , Patients With Advanced Hepatocellular Carcinoma , Gt 30 Study , Nct04251117 , Sbchb , D , Racp , Mnzm , Phd , Geneos ,