Writing in Chemistry & Biodiversity, researchers from the Italy’s University of Florence and Poland’s University of Science and Technology in Wroclaw reviewed the cosmeceutical peptides market, identifying methods and technologies from scientific literature and patents used to overcome bioavailability and stability challenges. Peptides are interesting ‘bioactive cosmeceutical ingredients’ Peptides, the researchers wrote, could be considered “an interesting group of bioactive cosmeceutical ingredients” that had garnered rising attention in recent years. However, bioavailability and stability of these peptides when used as actives remained “one of the most relevant problems in both drugs and cosmetics”, they said . “Although in the past five years, nearly 200 review articles dealing with cosmeceuticals appeared in [the] PubMed database, only six of them address the problem of active ingredient permeation.”