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Peixuan Guo, the Sylvan Frank Endowed Chair in Pharmaceutics and Drug Delivery and the director of the College of Pharmacy Center for RNA Nanotechnology and Nanomedicine, is The Ohio State University 2021 Innovator of the Year.
Guo is a pioneer of RNA nanotechnology, developing RNA particles that target tumors. His work has led to several discoveries: the RNA rubbery property that leads to more efficient cancer targeting without toxicity, novel methods for lung and liver cancer therapies, and a simple and fast method for diagnosing COVID-19 earlier in infection.
He first proposed the concept that cells have many small RNA molecules with novel yet undiscovered functions, and named them “sRNA.” Guo is the founder and chairman of the board of directors of ExonanoRNA LLC. He has raised more than $4 million of funding for the company to develop RNA nanoparticles for cancer therapy.