Mid-Southerners react to CDCâs new face mask recommendations CDC: Fully vaccinated Americans do not need masks for most activities By Kelli Cook | May 13, 2021 at 10:43 PM CDT - Updated May 13 at 11:10 PM MEMPHIS, Tenn. (WMC) - Doctors now say people who have been fully vaccinated no longer need to mask up in most situations. Around this time last year, the Centers for Disease Control and Prevention (CDC) first recommended wearing a mask. Now, the CDC says itâs time for a change. Itâs now official. The CDC says if youâve been vaccinated for COVID-19, you can ditch your mask for many outdoor and indoor activities.