Lundquist investigators in global study expanding genomic re

Lundquist investigators in global study expanding genomic research of different ancestries


Credit: The Lundquist Institute
LOS ANGELES (May 31, 2021) -- Today The Lundquist Institute announced that its investigators contributed data from several studies, including data on Hispanics, African-Americans and East Asians, to the international MAGIC collaboration, composed of more than 400 global academics, who conducted a genome-wide association meta-analysis led by the University of Exeter. Now published in
Nature Genetics, their findings demonstrate that expanding research into different ancestries yields more and better results, as well as ultimately benefitting global patient care. Up to now nearly 87 percent of genomic research of this type has been conducted in Europeans.
"We are very excited about contributing to this global study," said Dr. Jerome I. Rotter, Investigator and Director of the Institute for Translational Genomics and Population Sciences at The Lundquist Institute and Professor of Pediatrics and Human Genetics at the Geffen School of Medicine at UCLA. "It is highly significant that this global study is multi-ethnic and trans-ethnic. Such multi-ethnic studies are a major strength and focus of the cardiometabolic genomic epidemiology at The Lundquist. Our studies examine type 2 diabetes, coronary artery disease, hypertension, cardiac arrhythmias, and fatty liver, as well as studying their risk factors and related traits such as insulin resistance, dyslipidemia, and obesity."

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