Introduction Adopting IFRS Standards is a top priority for many stakeholders in economies in the Mekong region. Such countries in the Association of South East Asian Nations (ASEAN) are suffering from the impact of Covid-19 and are looking to attract foreign direct investment to speed recovery and grow. IFRS Standards adoption will assist greatly in this goal. It is therefore helpful to look across the Mekong region to assess the state of adoption by respective nations, and understand the successes and challenges therein. Representatives from Myanmar, Laos, Cambodia and Vietnam gathered at an online conference hosted by the ASEAN Federation of Accountants and ACCA to discuss the challenges and benefits of implementation, and to hear from representatives from the International Accounting Standards Board (IASB), the Big Four, the World Bank and a recent successful adopter, Malaysia.