Luckily, there is help. Below are some tips, research findings and resources that could help motivate and inspire you stick with those resolutions. But first, you might need to detoxify from the holiday festivities. Detoxification Detoxification is a natural, automatic process that occurs in the body 24 hours a day. We can support our body's ability to detoxify through positive lifestyle choices such as enhanced nutrition, limiting toxic exposures in our environment, exercise and stress reduction. The liver is the major organ for detoxification. For the liver to function well in its job of detoxification, it requires nutrition: adequate protein is essential to this effort, and many vegetables and herbs can help.