Share this article Share this article GAINESVILLE, Fla., March 11, 2021 /PRNewswire/ -- Evolugate, LLC, a Gainesville-based biotech company, has demonstrated that its proprietary technology can be used to improve the throughput of plasmid DNA manufacturing. Plasmids are essential for nucleic acid-based vaccines and gene therapies. Efficient plasmid production represents a significant bottleneck in the large scale manufacture of several Covid-19 vaccines. Evolugate, LLC Plasmids are mass produced in bacteria and Evolugate has demonstrated the ability to increase plasmid production from 2-7 fold in two different strains of bacteria. One is a proprietary strain currently under development in-house and the other is a common, commercially used strain.