Conference in berlin this weekend and has committed himself in principle to a cease fire. Plus from flames to flood much needed rain blankets australia after months of catastrophic bushfires but parts of the country are now struggling to cope with the downforce and theres more rain in the forecast plus how much would you pay for life saving medical treatment we need to want baby boy whose gene therapy cost a staggering 2000000 euros is cases for candidates about the ethics behind the crushing cost of some cutting edge to treatment. Im calling thanks for joining us the wrongs of Supreme LeaderAyatollah Ali Khamenei has said donald trumps. Support for the iranian people is a pretense now in a rare sermon during friday prayers in tehran he accused the us president of wanting to push a poisoned dagger into the countrys chest he also called irans airstrikes against the u. S. In retaliation for the killing of general hossam sort of money a quote day of god. After weeks of National Trauma thousands turned out to see irans Supreme Leader in a rare show of strength the main cheered in chanted as ali how many railed against irans enemies. A spokesman for the wicked governments of america keep saying that we are standing with the iranian people you are lying if you do stand with the iranian people it is because you want to stick your poisoned dagger into the chest of the iranian nation you havent been able to do that so far and you wont be able to do a damn thing. His intervention comes after the countrys top military commander was killed by u. S. Forces earlier this month triggering a nationwide outpouring of grief and a tragic stampede which saw scores killed. Then came what iran said was an accidental dining of a passenger jet killing all 176 people on board. Angry protests engulfed the capital. Of the. Year. Lamented the crash but said iran was being manipulated. Some people followed guided by American Television english radio try to portray this incident in such a way that the deaths of these 2 masses would be forgotten your mojo your. I message haired loud and clear by president rouhani who sat among the washed. The ayatollahs presents underscores the crisis the last time he delivered friday prayers in 2012 amid a standoff over its Nuclear Weapons program in russia. Well joining us now is journalist amir abbas hes in tehran for us hes been tracking that story amir the last time that how many spoke of friday prayers was 8 years ago that was 2012 so whats the significance of his speech today and what did you make of what he actually. The significance here today is that 4 says that after 8 years the speech is important because a colony leader has the origins are as great always of your own political factions as to come in the final say in the situation now the situation has become pretty complicated with the an assassination of general still in money. Of the plane and the people who were lost their lives in this and the during the morning so this even if you can see here it is that works on what the leader today said is the final say after everything that. General rule on the and everyone else said and the main point 0 think the main takeaway is so poor showing the oral its a good way truong behind the ear on the strike on the u. S. Bases in iraq the missile the strike and the fact that this was a retaliation for a general feeling with this killing and other things that have happened planes absent all downy other People Killed in protest nothing should be distracting the 19 on this almost certainly see part of the narrative those pictures of his supporters there those prayers now enormous pressure of course for many some calling him for it to resign actually but we also heard hes pushing his own narrative now that 4 nations are trying to manipulate the downing of this plane how is that narrative being received any wrong could that take some of the pressure off of him. Oh well the speech did not exactly address any of the protests and if the chance or even the plane downing itself specifically. Of course as you seem the most of the it was about the missile is a strike down the general someones assassination the media end of it is that. Plane downing exactly was not. Was not. Considered main point in all of this did in the pressure world when the borrowers are on the Supreme Leader comes in to speak the other factions are going to at the end of it to lisa to listen and your contesting with a team that means so i would say this can be a sleaze inside iran that is inside your own political factions and the Ruling Authority that there wont be any watch more of pressure. Here briefly if you can is there anything that harmony can do to ease those tensions now within his own country. Oh well it all the 1st what you call those tensions within the country well the protesters up after the plane crash they were asking for. For us least the resignation of some of those people involved on that could be a lot of people if theyre waiting for that and maybe as the president won he said maybe a special court or. Something to address the situation i think the leaders talk today was not exactly a change in tone regarding everything that was going on inside iran or anything that goes on this Foreign Policy so the idea i think is at the end that the situation is rather comfortable with this issue asian right now and does not seek to change anything in order to receive any different narrative ok journalist amir have asked the interim for us thank you very much. Thank you bonnie well germany is preparing for sundays International Peace conference on libya bringing together the main warring parties and their powerful International AlliesGerman Foreign minister has been in beit ghazi for talks with rebel leader general how the phone after are who has now agreed to attend that conference was also told last that he agreed in principle with a ceasefire and Prime Minister fayyad yes also russia leads libyas u. N. Back to government has already signed a cease fire deal are currently controls the majority of eastern and southern libya the berlin summit follows failed efforts by russia and turkey to get him to sign a truce and halt an offensive on the capital of tripoli. I have a lot of players here we want to bring in Political Correspondent simon young for a look at what will likely be a very high stakes summit in berlin simon 1st of all just walk us through who is likely to attend this meeting and just as importantly who likely wont be there on sunday. Yeah its going to be a very high level meeting unusually so with so many leaders chancellor merkel has invited heads of states and governments are going to have president mccrone of france Prime Minister johnson of the u. K. But also secretary of state pompei o from the United States and the egyptian president sisi the turkish president the one and Vladimir Putin of russia has also said today confirmed that hes coming in addition to that youve got various International Organizations the e. U. The u. N. The African Union and so on as well as the leaders of the 2 warring factions have also said that they will be here on sunday so it will be an extraordinarily high level summit as to those who are coming yes tunisia is very unhappy that it hasnt received an invitation especially surprising because i could mass the German Foreign minister was there recently and he acknowledged that tunisia has been one of the countrys most affected by the conflict in libya so thats a bit hard to understand the other country that unhappy i think is greece theyre very worried about and in energy deal deal covering gas in the mediterranean thats been signed between libya and Turkey Greece is worried about that would like to be here the german position on that is saying that issue is being dealt with elsewhere in the council not at sundays meeting certainly a big and important guest was there despite those missing tell me a bit more about this conference now or is there a chance that be could see either peace or at least some sort of cease fire come out of these meetings on sunday. Well the main focus of sundays conference i think is on the International Partners the backers of the 2 warring factions to get them to commit not to send troops and arms as theyve been doing. To the various sides on the one side youve got egypt russia in the u. A. E. Supporting general have to are on the other side turkey in particular supporting the unity government in tripoli and its very important that those countries be able to speak and find a common path other countries have also got interests because of the. Raw materials in libya and also the fact that that country has become a conduit for refugees if you can get those countries to agree that will be good but obviously the 2 warring factions need to reconfirm that theyre sticking to the cease fire are i did a Political Correspondent simon young thank you very much as we heard the libyan ceasefire talks will take place here in berlin on sunday and of course the w. Will be there to bring you the latest developments as they happen lets take a look now at some of the other stories making news around the world we now know that at least 11 american troops were in fact injured when iran attacked bases hosting u. S. Troops in iraq on january 8th washington had previously claimed that there were no casualties or injuries in those attacks which was in retaliation for the killing of iranian general hossam sort of money ukraines Prime Minister or lexy hunt charo as submitted his resignation to president a lot of years of lenski he confirmed the move in a Facebook Post you see it there comes days after one torak was caught on tape saying the president knew nothing about the economy and says the recording had been doctored. Farmers across germany are protesting against the governments agricultural policies many in the industry say tighter rules limiting the use of fertilizers and low Consumer Prices are squeezing their incomes hundreds of farmers in tractors have descended on berlin in an effort to raise awareness. I want to take a look now at australia where rain is bringing some much needed relief to parts of the country affected by months of devastating bushfires but those downpours are also bringing new problems in the form of flash floods and with more rain forecast in the coming days australians are finding themselves moving from one whether driven crisis to another i. From flames to flash floods just a week ago staff at this nature park were protecting their animals from oncoming bushfires now theyre having to deal with another extreme theres the dr who is also saying absolutely united could. Never go to the whats coming in the park a wall of water. Starts rushed koalas to safety. Back might be. Well for creatures more used to the way it was more about keeping them in their place. Heavy rain has fallen across New South Wales one of the states worst affected by bushfires in the state capital sydney residents were remembering how to use an umbrella the orange hair use that had taken over the citys skyline now cloudy grey. We need a bit of rain in order to help the 5 is special it is how dry it was part of the day and i think it will help with the hayess just push everything out there this is what is in many many months weve only got about 4 days of rioting in the last 4 months. And not run of only children but this is well and truly the little for very little. For many in the country the way weather has brought relief and joy. More a case of sliding than singing in the rain. That rain has helped the not. Of the raging bushfires but it does bring with it another threat of danger weather doesnt automatically mean changing fortunes. Of Pharmaceutical Company novartis has announced that it will use a lot of resistance to supply the worlds most expensive drug to children suffering from a devastating genetic disease called spinal Muscular Atrophy but only 100. 00 Children Worldwide will receive that free treatment which usually costs millions of dollars the astronomical price of such drugs has triggered ethical debate. Michael story sounds like a modern fairy tale but it also poses questions he was born with spinal Muscular Atrophy a life threatening neuromuscular disease when his condition deteriorated despite treatment his family launched an Online Fundraising campaign the aim for him to receive a gene therapy thats not yet licensed in europe he actually gets. Worse. By the treatment cost almost 2000000 euros professional athletes and celebrities lead their support bowing to pressure from the public the Health Insurance company agreed to pay michael received the most expensive therapy in the world. That. Grew thinner and as it was a miracle that it worked at all then on the 3rd day we had another miracle wonder that he could turn himself over properly and in the 2nd week he even sat up on his own. The joint was shared by very many online supporters but there are other opinions about the treatment. Some say not enough tests have been done to guarantee its safety more parents have been demanding access to it Health Authorities are sounding the alarm. This is about our promise of healing us and i really hope its one that will evolve. But we still dont know if it will be and so this is a game of hope of one happening outside the normal system so its not how we should be doing things. Then the manufacturer novartis has issued a statement on its product the decision to implement the therapy must be made by specialized doctors under careful consideration of the risks on an individual basis and we are prepared to offer financial concessions to Insurance Companies. But this Case Highlights another major question in a Public SectorHealth Care System how much may have treatment cost many expensive gene therapies are set to gain market approval in the coming years what kind of results justify what kinds of costs at the University Hospital in bonn dr youn band meets families who have the prescription that costs 2000000 euros he says it doesnt make sense yet to start prescribing the therapy on a wider scale i think if you want to do it with very new kinds of therapies where were not sure how effective or safe they are we need consensus between all parties between specialist doctors experts centers Insurance Companies and licensing authorities only then can we properly decide which patients we should treat with a therapy thats at such an early stage. Michael seems to be doing well so far although no one knows if the 2000000 euro medication has really healed his disease for good still his story shows how vital it is to regulate costly new gene therapies. Im joined in studio by our science correspondent Derrick Williams thank you for being here. We saw the piece but but can you just explain for us how exactly do these sorts of gene therapy treatments work ok well gene therapy treatments are are different than than conventional treatment treatments in the sense that theyre theyre not pills theyre not theyre not things that are that are going to be taken on a regular basis its a single therapeutic step which is the injection of what are basically viruses into your body now the reason that theyre injecting those viruses into your body is because a person who has a genetic disorder has got a broken gene theyve got a faulty gene somewhere that codes for a more or less important protein and these protests if you get a faulty gene youre going to end up having a faulty protein protein so what you need to do is swap out that code for something thats intact and so what these viruses do theyve been genetically altered to carry an intact version of that particular gene and if you get them into the bodys cells then the virus invades the cell nucleus and the cell begins to produce the protein at least in theory so there is certainly a lot going on in these vials here we see behind us how can Something Like this 111 therapy treatment cost 2000000. 00 why is this so expensive when this this goes back to the sort of basic Business Model that they have in the Pharmaceuticals Industry as i said its not the these things new drugs are not they dont really fit within that system for decades weve been selling you know Pharmaceuticals Companies have been aiming at managing your health care by selling you medicines the same medicines often over and over and over again possibly to the end of your life in the case of Something Like ive pretensions and so there their model is built around selling a lot of medicine what do you do when youve developed a drug that fixes the problem with a single treatment you still have the research and the development that go in. To the drug and thats a very very expensive process only bust them fewer than one in 10 drugs actually makes it through to through the approvals process so how do you how do you then the money that youve invested in in your development and you do that by saying ok we have a single treatment but that single treatment is going to be very very expensive course a critic might say you know