TORONTO -- Nearly a year after the first infection was found in the province, Ontario reached a significant milestone in the fight against COVID-19 on Dec. 14, 2020. On that date, the first dose of a vaccine against the novel coronavirus was administered in the province. Personal support worker Anita Qudangen’s shot was followed by applause as she sat in a chair inside a downtown Toronto hospital. Since then, amid substantial supply issues, more than 250,000 people in Ontario have been fully vaccinated against the disease. Now, as more doses become available and more needles go into arms across the province, many questions remain.