Toe2Toe originated from an unlikely friendship between a medical student and a homeless man. The medical student, Chris Costello, actually met Matt, the homeless man, while he himself was a patient at a hospital. Being inquisitive and genuinely curious about his roommate, Chris would ask Matt about his experiences as a homeless person and he ended up asking what could the homeless population use to help them with their day-to-day life and Matt promptly replied "socks". That was the beginning of the non-profit organization, Toe2Toe. Chris held several internships as a medical student in various geographical locations across North America, and he observed that homeless people had an increased probability of getting foot infections versus the population at large. It was a constant theme regardless of where he interned. After meeting Matt and having those significant conversations, he knew the solution to this problem was simple: clean socks for the homeless.