one of the doctors who helped develop the new treatment joining me live. in indonesia, a volcanic eruption forcing people to outrun huge clouds of hot ash. a statewide man hunt, overnight arrests and finally a virtual arraignment of the parents of the accused michigan shooter. james and jennifer crumbley entered not guilty pleas to the charges files against them. the sheriff held a news conference a short while ago. what did he have to say about what's transpired the last 24 hours? >> reporter: we learned a few things. we learned james and jennifer and ethan crumbley are all being held in the same place not far from here. they are in isolation. the sheriff said it's likely ethan doesn't know his parents have been arrested because they're held in isolation. we heard about a thuird person who helped james and jennifer get into that warehouse where they were hiding. here's what michael bouchard had to say about that. >> we believe they were assisted in that location to get there, to get in and we're gathering that information and we're going to have the totality of that done fairly soon and present that to our prosecutor for potential charges for either aiding and abetting or obstruction of justice. >> reporter: i have a few more details about what transpired overnight. my colleague said that person of interest was caught on surveillance video helping guide the crumbley's car into the parking spot at the back of bidding where they were eventually found and letting them into the building. detroit police may it clear they did not break in to this warehouse where they were later found, locked inside an art studio on the third floor. so clearly some difficult times, many hours looking for them fou each of the manslaughter charges carries up to 15 years in prison and a $7,500 fine. very serious charges the parents are facing. the prosecutor saying they are criminally negligent and that's is why she's taking this rare step of bringing charges against the parents of a suspect in a high school shooting case. phil? >> athena, thanks so much. joining me now cnn legal analyst and criminal defense attorney my friend joey jackson. police and prosecutors say the parents were on the run. defense attorneys say they were in fear for their safety and they always planned to turn themselves in. how does their disappearance impact the case against them? >> that will be a question of fact. the attorneys during arraignment making very clear there was a miscommunication with the prosecutor with respect to the time they were to turn themselves in. if you look factually, i don't know it was a secret they were being pursued by law enforcement. i don't know it was a secret that their presence was required before the court and obviously you have this revelation with respect to where they were warehoused, how they got into that location, the fact that they were trying to secret themselves. so that does not appear factually and common sense wise they were simply waiting to go to the arraignment and they did not attempt to abscond from justice. how it plays into the case will be it goes toward consciousness of guilt. where you're in an instance where you appear in court to face charges, it doesn't make you innocent but it means you're ready to fight the charges and you're not otherwise concerned or evidencing a guilt to run away. i i think that's how prosecutors will use it here, they knew they were guilty, hence they were on the run, they took out $4,000 and that authorities will say would have been to have aided them on the run. >> putting aside the bizarre event of last night, there's a reason there's not a lot of precedent for charges parents for cases like transpired in michigan. >> i think it's a great question. i think what this prosecutor has done is made a judgment and said school shootings around the country, legislators around the country are not looking to really adopt responsible gun laws, the congress is not looking to do it. well, you know what, i'm going to do it. how? i'm going to do it by using the current existing law to demonstrate that they are equally as responsible. and what are they doing with regard to that? if you look at the count as we look at there, involuntary manslaughter, what does that mean? it means that your conduct created a risk because it was unreasonable of death or serious bodily injury. ask yourself the question did the conduct of the parents create an unreasonable risk of death or serious bodily injury to others. then what prosecutors will do is factually look. did they purchase the gun? answer yes. did they secure it properly for their son? no, they did not. did they give it to him? were they aware with respect to his conduct, the fact he was having issues in school. he was spoken to by the teachers, for example, being se searched for ammunition. he was spoken to with regard to the parents with the drawings he made. people are dead and i'm going to hold you as the prosecutor responsible for this horrific s circumstance. >> by all accounts there were numerous red flags that weren't acted upon that will almost certainly be civil suits again the school. do you see any possibilities for school administrators, teachers, they could also face criminal proceedings against them or the school itself? >> so i don't know that it rises to the level of criminality with respect to the school officials. when you look at crimes, it a different standard by which we judge your carelessness. it's the gross misconduct that's involved there and many would argue that this was. however, i do see a path for civil liability. now, it should be made clear that civil liability relates to money, not contract but money. the parents here think what do you mean money? i don't care anything about money, i want my children. at the end of the day in the event that the school created this unreasonable risk because they knew something was amiss and didn't do enough about it, that creates a standard of wanton misconduct and i think that will be looked at very closely as it relates to civil lawsuits moving forward. >> joey jackson, as always, my friend, thank you very much. >> and we'll be speaking to the oakland county michigan sheriff, michael bouchard, about the case in our next eastern hour. now, to our breaking news tonight, it involves the business of this network, cnn, "primetime" anchor chris cuomo no longer just suspended, he has been fired, terminated immediately, a decision by corporate leadership following a review by an outside law firm. that firm looked into how much h help chris cuomo gave his brother on his allegations of sexual harassment. let's get to brian stelter. brian, our bosses here at cnn are making it very clear that what emerged during this investigation gave them no choice, essentially chris cuomo had to go. >> that's right. that is something that developed as this week went along, phil. i've been doing reporting on this in the past few minutes. i try to treat these stories that involve cnn as i would fox. we know on tuesday he's suspended pending evaluation. there was a chance he could come back after a punishment period. an external, third-party law firm was hired to look into this matter. that's something we didn't know until tonight. this law firm returned a report on friday. whatever that law firm found contributed to the decision on saturday, today, to terminate chris cuomo. that decision was made by the head of cnn, jeff zucker. he notified the staff here on saturday afternoon and now it is making -- sending shock waves across the tv world on saturday night. here the statement from cnn saying cuomo was suspended after a review. it says despite the termination, we will investigate as appropriate. this suggests something emerged between tuesday and friday that l led to this decision. i received questions worried about cuomo's staff, what happens to the producers? the answer is nobody gets cut away, no one goes away, that staff remains in place to produce the p.m. hour. that is good news for those staffers and a relief because i know there are a lot of people out there that love "cuomo primetime," loved the program and those producers will remain in place. this is a matter of journalistic ethics and standards, about what cnn could tolerate over time. though there was an acknowledgement that family comes first and he was in a difficult situation as his brother was challenged and scrutinized and had to resign due to sexual harassment allegations, that was very difficult for cuomo. cnn stood by him but something happened, we don't know what, that did lead to his termination today. >> it was the involvement of the law firm and additional information. it's new tonight and it's what everybody is trying to figure out. brian, chris occupied that very important 9 p.m. primetime time slot. what do you know about the future of the night lly rundown here? normally michael fills in for him. i believe that is the plan for this coming week. i think the insider story is about the drama internally, different people's feelings about it but the story that really smamatters is about journalistic values. people need to trust the content, even if there are these one of a kind situations where you have an anchorman and his brother is a governor embroiled in a scandal. this is a very difficult situation and is being untangled in some ways by the termination of his brother. >> up next, the incredible story behind merck's ground breaking anti-viral pill. >> then an eruption in indonesia forcin forcing people to flee huge clouds of hot, volcanic ash. the real honey you love... plus the powerful cough relief you need. mind if i root through your trash? 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(burke) seventeen-car garage you got there? ♪we are farmers♪ ♪bum-pa-dum, bum-bum-bum-bum♪ hi sabrina! hi jen! hi. so you're the scientist here. i just have to ask. does my aveeno® daily moisturizer really make my dry skin healthier in one day? it's true jen. really?! this nourishing prebiotic oat formula moisturizes to help prevent dry skin. one day? for real! wow! aveeno® healthy. it's our nature.™ i gotta say i'm still impressed. very impressed. new daily moisture for face. everything you love for your body now for your face. tonight a behind-the-scenes look at what could be a major development in the fight against covid. within days the fda could decide on whether to authorize a pill to fight the virus. it could reduce the risk that a covid victim will face, severe effects or death, by 30%. the capsule would be the first oral anti-viral treatment available. it doesn't come without concern. it was narrowly recommended an emergency use authorization. those voting no were concerned about effects on unborn children or side effects. we'll continue to watch the debate over this ground breaking pill but tonight we want to tell you the back story. none of this would have happened without it man, george painter, a scientist at emory university in atlanta. he's known as the drug hunter. he discovered the drug and began studying its power nearly a decade ago, long before can covid-19 came along. six years ago painter wanted to see this man, to see what he was working on. he's the director at vanderbilt university medical center. he joins me tonight. sir, thanks so much for joining us. you first heard about this drug over lunch, if the stories i've read are accurate, in birmingham, alabama. can you take me back to that day, what your first thoughts were when this was laid out to you. >> george painter had been an adviser to the other drugs we were looking at, recommz vir. i said i got to get home, george. high said i whe said i want you a look. i said this is amazing. we took the drug to vanderbilt and it was phenomenal in terms of its capacity to block at the time mers and sars, not covid because covid wasn't around. this was in 2016. >> you very clearly recognized early on the potential or kind of to the way you're describing it the amazing potential this could have. when did the label come on for the covid perspective? when did it click this could work for covid? >> before covid, i would say. because our goal in all of our testing was to find a drug that would work against every coronavirus. we tested it against a mouse virus, against sars, mers, bat viruses with colleagues at north carolina. we knew it would work against any virus with significant confidence. so we just tested it and demonstrated that and were able to show that very rapidly it would work. >> in terms of how it works, you've described this in the past of being like nails to a car tire to some degree. can you explain that a little bit? >> i like analogies. you know, when we think of things for the spike, there are -- i guess another analogy i might use is a truck driving up to a factory and going into to try to remake that factory and the factory is the cell. the spike is the key to the door. inside the virus assembles a new assembly line. and this drug targets that assembly line. it basically introduces damage. it's like taking a hammer or something else and hitting that assembly line so it can no longer make new cells. it just induces incredible damage in the virus. so the viruses that come out, not only are there fewer of they, the ones that come out are damaged and can't cause infection at all. >> you saw or heard me spell out some of the pushback from the fda advisories earlier this past week. what would you say to your colleagues in the scientific community that have concerns about this moving forward? >> i'd say we need to do a little better job at thinking about the science. some of the things i heard i felt like i didn't recognize the potential. for example, this drug does cause more mutations in the virus. so concerns were raised about whether that would cause a virus that was more dangerous. but in fact, it causes so much damage to the virus and decreases -- if it makes a ten-fold increase in mutation, it makes a 10,000 fold decrease in how much virus is made. the person treated with this would have less mutations coming out than the person who doesn't get the drug. so we need to really understand the science and be led by it and not by concerns that are sort of founded in sort of almost what i would call science fiction. >> can i ask given what we've seen over the course of the last six or seven days, the way you're describing it makes it sound like if there's a new variant, omicron as bad as people predict or something else, that wouldn't affect your ve view of the effectiveness of this drug. >> i've looked at the sequence of omicron and there's one enzyme that is targeted at this case. there's no relationship about the immune response in the spike. we need this drug and protease in inhibitors and targeted in multiple, multiple ways. >> the back stories are always most fascinating. dr. mark denison, thanks so much for your time, sir. >> my pleasure, thank you. >> more delays and signs that members of the trump administration are looking to deny answer to congress. and more pr legal afrom legal a pree every day in business brings something new. so get the flexibility of the new mobile service designed for your small business. introducing comcast business mobile. you get the most reliable network with nationwide 5g included. and you can get unlimited data for just $30 per line per month when you get four lines or mix and match data options. available now for comcast business internet customers with no line-activation fees or term contract required. see if you can save by switching today. comcast business. powering possibilities. new showdowns could be coming as soon as next week in the january 6th committee work for answers. mark meadows is expected to testify. it could all fall apart over questions of supposed executive privilege. that same claim bought steve bannon an contempt of congress indictment. mark meadows, however, is happy to talk about his new book, which democrats say is a sign he doesn't have much ground to stand on over the privilege claim. jeffrey clark had his appearance postponed for two weeks because of a medical issue. he's facing a contempt charge and refusing to answer questions in a recent deposition and failing to hand over documents. who is jeffrey clark? it's not necessarily a name we heard often or really ever for most of trump's administration. we've learned he was very active in efforts to overturn the 2020 election. so here he is. at the end of the trump presidency, clark was the acting head of the civil cases at the department of justice. in the weeks after the election, he pushed unfounded claims about voter fraud. he's also accused of helping donald trump create a plan to oust then acting attorney jeffrey rosen and take the job himself and attorney general. it's thought that clark would have probably helped lawmakers in georgia and other states potentially undermine the results of the popular vote. so leaders in the department of justice say they told trump if he made clark attorney general to overturn biden's lelections, many if not all of the senior officials would resign. a report by the judicial committee slammed clark and asked for a view of his professionalism as a lawyer. as to the possibility that clark would refuse to testify, democrats say that's not normal. >> i don't know if it's unprecedented but it's certainly unusual. and yet the fifth amendment like the rest of the constitution is there for everybody, including former department of justice officials. i will say jeffrey clark's superiors, his bosses at the department of justice have none of these problems. they didn't try to assert the executive privilege and are not raising a fifth amendment privilege against self-incrimination now. >> we want to untangle this. we bring in cnn analyst and former prosecutor preet bharara. as a form er prosecutor, how important could clark's testimony actually be? >> i think it's pretty important. as you point out, he was a behind-the-scenes figuring name not well known but figured prom ne prominently behind the scenes even when the acting attorney general and deputy attorney general were casting him away and his conspiracies on the side with the then president of the united states to try to undo the election in georgia and in other places. it's been reported he had direct commun communications with donald trump and officials in georgia and other places. i think his testimony is pretty on point. >> you're pleading the fifth because you don't want to implicate yourself. does anything you've seen or heard about what jeffrey clark did constitute any kind of crime? >> there could be. that's why people are looking at it. there's a district attorney in fulton county georgia looking at charges and liability up to including potentially the former president of the united states. some people invoke the fifth amendment right against self-incrimination in bad faith. sometimes it's done in good faith. here we don't know which of those it is, but given the nature of what he was planning, given the strident opposition he got and threats of resignation he got and that were transmitted to the then president trump from the acting attorney general and others, it seems like he was certainly very, very nefarious and certainly a possibility that it was criminal, yes. >> to move on to another individual we didn't hear a lot about until these investigations kicked into gear, lawyer john eastman. he helped draft a plan for then vice president mike pence to interrupt vote certification. why would a lawyer worry about incriminating himself if he's just crafting legal strategies? >> because maybe he's doing more than that. that's one reason why he might not have attorney/client privilege. if you were engaging with your client, who you otherwise represent in a criminal conspiracy of some sort, then you don't get the protection of the attorney/client privilege. so that's meaningful. the other thing i want to say is everyone in america has the absolute right to assert the fifth amendment privilege against self-incrimination. and if it's done in good faith. and you probe whether it's good faith or not, which i assume the commit will do. it's a thing that the former president who is at the center of this, donald trump, who said the only people who plead the fifth are people who are guilty. that was donald trump's view so i wonder what he thinks of this. >> and i want to turn now to this new book, revives the bug l big lie, he white washes an attempted coup. can they use the word in the book to undercut husbais own cl of executive privilege? >> whether it was in a document or in a civil case, it can be used against him. presumably he chose his words carefully. he may have been in a different frame of mind when he wanted to sell the book and may have heard himself. there's this kubuki dance going on between meadows and the committee. first he was going to be fully defiant and then cooperate a hill bit. the effect of the indictment had an impact on mark meadows who wants to figure out a way based on the reporting i've seen to do the bare minimum to avoid prison, also sell books and provide some testimony to the committee. >> do you think he can actually walk that line? >> i don't know. the committee is i think very tough. and i think the indictment of steve bannon has had a big impact and the threat to indict or make a referral for the indictment of jeffrey clark shows people they are very, very serious about this and they're not going to engage in nonsense because they know the clock is ticking and there may be only another year before the other party takes over. so i think it's a hard line to walk because the committee will hold his feet to the fire. >> last question but more broadly, as you game all this out, as somebody who lived through the trump impeachment where they just run out the clock -- first impeachment, i should clarify, and seemed to be part of the strategy at least at the start, one, do you feel like, as you noted, the bannon contempt charge did start to change the game and shift dynamics and, two, do you really think they can run the clock out for a year or can the committee figure out a way to get the information they need in that time? >> with when we come on television, we focus on the intransient people but among other people, jeffrey clark's bosses, the deputy attorney general came forward voluntarily, didn't throw up a smoke screen, didn't assert the first, didn't say they had executive privilege. and from the reporting that cnn and others have done, the committee has talked to 250 people and they probably reviewed hundreds of thousands of pages of documents and communications and we still got another year. are they going to get the testimony from everybody they want? no. will they ever get testimony from steve bannon, even if he goes to prison? probably not. but they will have a lot of testimony from a lot of folks, a lot of people have cooperated and they will get communication and some documents from third parties, even if the authors of those documents, one of the parties to those emails have defiant. there are other ways of getting those materials from other sources. i'm sure they're doing that. will they get everything possible under the sun? probably not. will they get enough to show us in a transparent way what happened on january 6th and who is responsible, i think there's a good shot. >> there's a lot going on that the public is not seeing, that you as a former u.s. attorney would know quite well. >> thanks for having me. >> we have this new video just into cnn. >> that makes me think of charlottesville. it's not. this group is marching across the washington mall and past the lincoln memorial just a short time ago. they're called the patriot front. they're wearing white masks, matching arm patches and some wearing plastic shields. they're largely considered white nationalists. one banner read "reclaim america." the group told cnn the march was permitted but the u.s. park police said the group does not have a permit, under like the unite the right protest, the police say this has been peaceful so far with no arrests. >> and north carolina is on the front line when it comes to tracking the covid omicron variant. cnn got rare access inside that lab and we'll explain why the lab's work is so important. he do your books for you. i'm linda, your quickbooks live bookkeeper. let's do this linda! sounds good! a live expert bookkeeper who understands your business. felipe, i've categorized last month's hair gel expenses. steve, i just closed your books. great, how are we looking? 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cnn got rare access to a lab that has already identified several confirmed cases of the omicron variant in the u.s. it is on the cutting edge of detecting the ever-changing virus. cnn's diane gallagher shows us. >> reporter: this is the front line in the hunt for omicron in the u.s. >> after you fin, that often uncomfortable covid test -- >> you're doing great. perfect. >> reporter: it's usually shipped to a place like mako medical laboratories. >> 10,000 square feet covid processing. >> reporter: they're taking samples from more than 40 states. >> 30,000 per day is how many we're processing right now. that's about 100,000 or so per week. >> reporter: labs like this are key in detecting the omicron variant in the united states because of what they do after identifying a positive test. >> as of right now we are at the point where we're sequencing every positive that we get. p p >> jegenomic sequences is the oy way to identify new covid-19 variants. they are one of only 60 labs that does sequences for the national network. >> i would say it takes two to three days to actually fully get the sequence from confirming a sample as positive to library prepping the dna and then actually sequencing that library. >> reporter: the world health organization and the cdc declared omicron a variant of concern after it was flagged by scientists in south africa. a mutation causes a peculiar test israel called an s gene dropout. >> n gene is the blue curve and the green curve is the s gene. >> it would normally up there with them? >> yeah. >> reporter: making a suspicious case easy to spot for expedited sequencing. >> we have about six samples that have that signature s gene dropout. >> reporter: sequencing is required to confirm omicron. scientists say they've seen many different variants throughout the pan demic. some like delta become the dominant strain while others fade quickly or don't take off. there's no way to know what type of impact omicron could have on the u.s. they agree knowledge is power. >> every time it transmits from a person to another person, it's another chance for the virus to mutate and change into something different. being able to monitor it really highlights the importance of testing, right, because without the testing you really have no base line to understand what's going on. >> reporter: one of those so-called suspicious samples did wrap up sequencing and it turned out it was not the omicron variant. there are still six that are finishing up that process. the expectation is the sequencing should be completed sometime on friday and those results will be reported to the cdc, but of course labs like this are receiving tens of thousands of new samples from covid tests every singling day. so these numbers are fluid and will likely change in the weeks to come. dianne gallagher, cnn, henderson, north carolina. >> after outrageous slurs, a commentator has apparently disappeared from the channel. i'll talk live with the new york board of rabbis coming up next. yes to clean and fresh ingredients! and yes to living life to the flavor-fullest. panera. live your yes. now $1 delivery. ♪ ♪ when the chapstick goes on. it's on. get yours on at chapstick.com [uplifting music playing] ♪ i had a dream that someday ♪ ♪ i would just fly, fly away ♪ . the prominent fox news commentator may be in the penalty box even if fox won't necessarily admit it. it's been five days since laura logan was last seen on air, drawing condemnation for comparing dr. anthony fauci to the -- listen how she sold the claim. >> what you see on dr. fauci, people say to me he doesn't represent science for them. he represents the nazi doctor who did experiments on jews in concentration camps. people all across the world are saying this. >> people aren't actually saying that. jewish groups are demanding she acknowledge her remarks. the son of holocaust survivor is with us, the first question i would ask is you see that on national television. what's your reaction when you see that comparison made? >> firstly, thank you for having me. as a child of holocaust survivors who are no longer living, who lost so many members of their family, i would say that if had there been more faucis then, many more members of my family and other families would still be alive today. it's offensive, it's outrageous. it should not have been said. >> now, fox hasn't commented on this yet. despicable remarks. i think everybody would acknowledge. do they need to condemn what she said? do they need to take her off air? what would you like to see in this situation? >> we have holocaust education, which is mandatory in some states, for young people, for high school students. after watching this, i think we ought to have holocaust education for adults as well. so one of the first steps has to be that those who utter these kinds of comments need to go through a real retraining, or reeducation process. and yes, it's got to be condemned. i think there is a responsibility, we have a moral responsibility. whenever someone says anything that is offensive, that desecrates the memory of people, that insults people, you can't simply be an innocent bystander. religion doesn't tolerate innocent bystanders. we have guilty bystanders. by the way someone once asked how did the holocaust occur? the answer is, you could get away with it. well, let's extend that. you can't get away with these kinds of comments. >> rabbi, here's what dr. fauci had to say when he was asked about lara logan's remarks, take a listen. >> not only is she being slanderous and disrespectful to so many people who were killed in the concentration camps by dr. mangoli, but she absolutely has no idea what she's talking about. she's completely incorrect in everything she says. what i find striking, chris, is how she gets no discipline whatsoever from the fox network, how they can let her say that with no comment, and no disciplinary action. i'm astounded by that. >> rabbi, lara logan seemingly doubled down this week, going after the auschwitz museum on twitter, which i didn't think was a thing. one woman's ignorance, prejudice, that's one thing but what concerns do you have when that person has an audience of hundreds of thousands if not millions to some degree. >> if you say it long enough, loud enough, people begin to buy into it. hitler made his comments over and over again and people who were educated, which is also always shocked me, phil, that we always say that education is the answer. well, education can make you smart. but not necessarily moral. you need moral education. so it's simply not enough for us to say it didn't happen. we've got to refute it with facts. i think people should look at what mangola did, look at those experiments, how he tore limbs apart, how he went after twins and tried to conjoin them. how he removed eyes so he could further the kind of nefarious experimentation. it's not enough to simply say this wasn't right. this is immoral. you've got to strongly condemn it, and there have to be consequences. >> it's a great point. read about him, if you aren't fully aware of what he did. rabbi joseph potasnik in new york, thanks so much for your time. >> thank you. the oakland county michigan sheriff is releasing new information about the arrest of the parents of an elgd alleged shooter. in indonesia, a volcanic eruption forcing people to outrun huge clouds of hot ash. you're in the "cnn newsroom." 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