The number of team infected by a Href='https://vimarsana.com/news/nmiss-tier'>Nmiss Tier yours Href='https://vimarsana.com/news/respiratoy-virus'>Respiratoy Virus has tripled over the weekend. In different corners of the globe a small band of scientists have been busy preparing for this moment. They say a new strain of coronavirus originated here. They looked like you or me. Hi but the Href='https://vimarsana.com/news/fate-of-the-world'>Fate Of The World is in their hands. A virus can get from one corner of the world to the other side of the world in less than 24 hours. Two cases have been identified in a couple with no known travel history. Fmore cases pop up outside o china. It was a sense of something was coming and i couldnt tell how big it was going to be. The first cases of covid19 set off a desperate race. The vaccine against the virus. Covid19 is our absolute worst nightmare. Vaccines are mission critical. Vaccines have saved more lives than just about any other public health intervention. Scientists say the virus is getting stronger. This is very hard to contain at this moment. They are the Href='https://vimarsana.com/news/special-forces'>Special Forces of science. All of these people were working around clock at a breakneck speed. Guarded by police with masks. More than enease, desperation. And if what they are creating works, they will say millions of lives. This is not just a drill. This is the real thing. We did not have time. The Href='https://vimarsana.com/news/coronavirus-pandemic'>Coronavirus Pandemic is worsening by the hour. For more than a year, we have been on five continents with the people doing whatever it takes. Currently have 200 freezers on site. Another 60 showing up today. My team spent about a half Href='https://vimarsana.com/news/a-billion-dollars'>A Billion Dollars before we had any idea if a product would be successful. Thats crazy. The Href='https://vimarsana.com/news/death-toll'>Death Toll at 26 million. 850 confirmed infections. And now they have a once in a century mission. To save all of us. The new Href='https://vimarsana.com/news/formula-virus'>Formula Virus is potentially more infectious. Its about protecting the entire world. This is Href='https://vimarsana.com/news/george-gao'>George Gao. He is the head of chinas cdc. His team immediately ordered up samples from patients in wuhan. And this is the actual Href='https://vimarsana.com/news/cct-footage'>Cct Footage from his lab as they got the first look at what might be causing the new illness. This was the first clue. From these images of infected cells it was immediately clear to gao they were dealing with a virus. But which type . An Href='https://vimarsana.com/news/electron-microscope'>Electron Microscope provided the first answer. It was still the first week of the new year. Now gao was staring at this. The very first images ever taken of Href='https://vimarsana.com/news/sars-cov'>Sars Cov 2. The Href='https://vimarsana.com/news/novel-coronavirus'>Novel Coronavirus. You could fit millions of these on the head of a pin. And they were about to change the world as we know it. There was a flash of recognition, a coronavirus, and it gave him a chill. Thats because in 2003 gao had been right in the middle of the Href='https://vimarsana.com/news/sars-coronavirus-outbreak'>Sars Coronavirus Outbreak in china which ended up infecting around 8,000 people and killed nearly 800. A terrifying 10 mortality. Was this sars again or something new . With modern rapid genetic Href='https://vimarsana.com/news/sequencing-technology'>Sequencing Technology they knew one thing. This wasnt sars. It was truly novel. But what was itting exactly . George gao was born into a poor family in Href='https://vimarsana.com/news/northern-china'>Northern China and rose to head up the Href='https://vimarsana.com/news/countrys-premier-diseasefighting'>Countrys Premier Diseasefighting agency. He knew the stakes were high and he had to tell the world. It is a Href='https://vimarsana.com/news/novel-coronavirus'>Novel Coronavirus. The race was on. Chinese authorities have traced a new deadly virus. They say a new strain of Coronavirus Has struck dozens of people and put an entire region on edge. Gaos team gave the world the first glimpse of its new enemy. Each Href='https://vimarsana.com/news/coronavirus-particle'>Coronavirus Particle filled with genetic instructions called rna and covered in a corona, or crown, of protein spikes. Inhale one of these viruses, and the spikes latch on to cells in our airways. The spikes then change shape, fusing the virus and the cell together. At this point the virus can replicate, and fast. And take another look at that spike. You will be hearing a lot more about it. While most of the world remained largely oblivious to the potential tHreat, Href='https://vimarsana.com/news/gaos-information'>Gaos Information on the new coronavirus started the starting gun for vaccines worldwide and they came out of the gates sprinting, eefrp with a different idea about the best way to create a vaccine. Gao himself races to begin Href='https://vimarsana.com/news/vaccine-development'>Vaccine Development in china. While in the united states, a little known Href='https://vimarsana.com/news/coronavirus-expert'>Coronavirus Expert takes a deep breath and steps into the spotlight. When the sequence of the virus came out on january 10th, we were certainly prepared and had determined exactly how we would make the vaccine in order to move very quickly. In australia, a new professor is out to prove himself. We saw the sequence. We thought, yes, lets make a vaccine. We will pretend this is the real thing. We will get a great publication out and we can pretend like we saved the world. In the u. K. , Href='https://vimarsana.com/news/vaccination-nol-jigst'>Vaccination Nol Jigst Href='https://vimarsana.com/news/theresa-lam'>Theresa Lam has been tracking it from wuhan. When she sees the sequence, it sends her scrambling. It was late Href='https://vimarsana.com/news/friday-night'>Friday Night early Href='https://vimarsana.com/news/sunday-morning'>Sunday Morning that i got the ski consequence. At 6 00 on Href='https://vimarsana.com/news/saturday-the-11th-of-january'>Saturday The 11th Of January with the latest Href='https://vimarsana.com/news/brr-bc'>Brr Bc got up the next morning and was in my bedroom in front of my computer basically huddled over in my pjs designing the vaccine. For a normal vaccine program, it takes up to ten years. But we didnt have that luxury. Professor lam works at the university of oxford. One of the worlds preeminent centers for Href='https://vimarsana.com/news/infectious-disease'>Infectious Disease research. The vaccines trickier body into thinking you have an infection. So you want a vaccine somewhat to mimic, to copy a natural infection. Facing infection, our bodies naturally fight back. With antibodies. Antibodies are a powerful defensive weapon against invaders. When a coronavirus attacks antibodies bind to the Href='https://vimarsana.com/news/spike-protein'>Spike Protein, blocking the virus so it cant invade cells. As our bodies fight off the virus, our blood becomes filled with these antibodies, which also helps protect us from being infected again. With the vaccine, the aim is to induce these antibodies without getting sick. They are almost like a trained army. So when they see a real virus, theyre ready to spring. Theyre ready to fight. Theyre ready to clear a real infection. Different antibodies fight off different pathogens. But the Href='https://vimarsana.com/news/oxford-team'>Oxford Team already had a Href='https://vimarsana.com/news/vaccine-technology'>Vaccine Technology that could be tailored to meet a specific new tHreat. We had designed a vaccine before against a coronavirus. So we had an idea about how to do it for the next outbreak that came. There are different ways of inducing or triggering antibodies. So were trying Href='https://vimarsana.com/news/build-something'>Build Something like a trojan horse. Oxfords way, a socalled viral Href='https://vimarsana.com/news/vexer-vaccine'>Vexer Vaccine is a smart delivery system. Its a common cold virus. We crippled it, so knocked the legs off it. It stunt replicate. What we have done is we have taken a small part of the new Href='https://vimarsana.com/news/coronavirus-and-weve'>Coronavirus And Weve put that into a common cold virus. That tiny part is the gene to produce the spike. And then once your body sees, this small part of the new coronavirus, and it amounts a strong Href='https://vimarsana.com/news/immune-response'>Immune Response to it. [truck horn blares] vo the subaru forester. Dog tested. Dog approved. Among my patients i often see them have Href='https://vimarsana.com/news/teeth-sensitivity'>Teeth Sensitivity as well as gum issues. Does it worry me . Absolutely. Sensodyne Href='https://vimarsana.com/news/sensitivity-and-gum'>Sensitivity And Gum gives us a dual Href='https://vimarsana.com/news/action-effect'>Action Effect that really takes care of both our Href='https://vimarsana.com/news/teeth-sensitivity'>Teeth Sensitivity as well as our gum issues. Theres no question its something that i would recommend. Derriere discomfort. We try to soothe it with this. Cool it with this. And relieve it with this. But Href='https://vimarsana.com/news/preparation-h'>Preparation H soothing relief is the 21st Href='https://vimarsana.com/news/century-way'>Century Way to do all tHree. Everyday. Preparation h. Get comfortable with it. brad how has apartmentsdotcom helped more renters get into new homes than any other site . By working tirelessly to design 3d virtual tours that are so realistic it actually feels like youre there. But thats all thanks to ted, a man who possesses an innate understanding of dimension. Uh. Ted. ted sorry, i was in the zone. Also my name is brian. brad apartmentsdotcom the most popular place to find a place. Out here, youre a landowner, a gardener, a landscaper and a hunter. Thats why you need versatile, durable kubota equipment. The Href='https://vimarsana.com/news/harrys-razor'>Harrys Razor is not the same. Our razors have five german engineered blades designed to stay sharp, so your eighth shave is as smooth as your first. And we never upcharge you for high quality. Harrys. Available in store and at harrys. Com. With the virus tHreatening to escape chinas borders the pressure was on for Href='https://vimarsana.com/news/vaccine-developers'>Vaccine Developers to move with unheard of speed. The head of the Href='https://vimarsana.com/news/world-health-organization'>World Health Organization is due to meet senior officials in beijing as efforts are stepped up to deal with the coronavirus outbreak. Growing concerns about the deadly coronavirus, it is spreading beyond china. The worries about a pandemic at this point . No, not at all. One person coming in from china, and we have it under control. Its going to be just fine. In late Href='https://vimarsana.com/news/january-2020'>January 2020 Href='https://vimarsana.com/news/president-trump'>President Trump, like most of the world, was underestimating the global risk. But there were some whose job it was to worry. I didnt know if we could beat it or not. We thought we had a way forward. Dr. Fwram is deputy direct i of the Href='https://vimarsana.com/news/vaccine-research-center'>Vaccine Research Center at the u. S. National institutes of health. The largest single funder of Href='https://vimarsana.com/news/biomedical-research'>Biomedical Research in the world. This is the reporter. Yes. And im testing some monoclonal antibodies. For the last two decades he has been on guard for almost every emerging new disease. Starting in early january, he drove their Href='https://vimarsana.com/news/coronavirus-vaccine-response'>Coronavirus Vaccine Response around clock. Well be able to do things faster, which is super helpful for the Href='https://vimarsana.com/news/clinical-trial'>Clinical Trials. This is all good. And remember that Href='https://vimarsana.com/news/spike-protein'>Spike Protein . Burning is laser focused on it. The spike is the main Href='https://vimarsana.com/news/surface-feature'>Surface Feature of the virus. The Href='https://vimarsana.com/news/nih-vaccine'>Nih Vaccine is based on a fascinating new technology. Mrna. This is the coronavirus spike gene. In Href='https://vimarsana.com/news/oxfords-vaccine'>Oxfords Vaccine they smuggle this gene into the body with an inactivated cold virus, a viral vector. Cells use the gene as a blueprint to make the Href='https://vimarsana.com/news/spike-protein'>Spike Protein, which, in turn, triggers an Href='https://vimarsana.com/news/antibody-response'>Antibody Response. An Href='https://vimarsana.com/news/mrna-vaccine'>Mrna Vaccine doesnt use a vector to deliver the blueprint. What you are looking at is the vaccine. Nothing but mrna wrapped in a cozy bundle of lipids, or fat. Using that genetic blueprint, your cells become little factories, churning out the Href='https://vimarsana.com/news/spike-protein'>Spike Protein over and over again to trigger those allimportant antibodies. So if you can put the blueprint of the mrna into the cell, that cell will build your structure. Simple and elegant. And barney thought it could produce a stronger Href='https://vimarsana.com/news/immune-response'>Immune Response. But all off this is brand new. From the outside it might have seemed like a risky bet, a hail mary. But if there ever was a time to try something new, this was it. I think the Href='https://vimarsana.com/news/4th-of-february'>4th Of February we already had researchgrade product to start our mass experiments. First mice, and then monkeys were given the new vaccine to see if it induced antibodies. Also protected the animals from getting sick. THree out of four of the mice that were dosed with one microgram were protected against viral replication in their nasal turb nens. The Href='https://vimarsana.com/news/lab-work'>Lab Work was led by Href='https://vimarsana.com/news/ki-sfwl'>Ki Sfwl zie corbett. Then just 34 years old. I was interested in coronaviruses because most other people were not. You want to build a niche. So you want to tap into some unchartered territory. Kizzy game came as Href='https://vimarsana.com/news/summer-intern'>Summer Intern in barneys lab. How did you envision yourself in 10 or 15 years . She said, well, id like to have your job. So that was unique in my years of interviewing students. At the start of 2020, when she was running a tiny Href='https://vimarsana.com/news/research-team'>Research Team of mostly students in the case of sarscov2 she could not have guessed she would be leading the charge against a global pandemic. That could be made. Thats what i was thinking. This virus is already spread globally and it is very hard to contain it at this moment. The president and the Href='https://vimarsana.com/news/coronavirus-task-force'>Coronavirus Task Force meeting with the vaccine makers. President trying to get a sense of timelines from the companies. In early march, as cases became more widespread in the united states, Href='https://vimarsana.com/news/president-trump'>President Trump launched a massive program to speed up Href='https://vimarsana.com/news/vaccine-development'>Vaccine Development. And flew to the nih for an update. In the room, the Href='https://vimarsana.com/news/brain-trust'>Brain Trust of u. S. Science. Most rigorous system in the world. The head of the nih, dr. Francis collins. Every time we have a challenge countrys top Href='https://vimarsana.com/news/infectious-disease'>Infectious Disease specialist, Href='https://vimarsana.com/news/anthony-fauci'>Anthony Fauci. You have been at this 20 years now. But its Href='https://vimarsana.com/news/barney-and-kiz'>Barney And Kiz zsfwi who greet the president. They block the protein. Barney tells him that the Href='https://vimarsana.com/news/animal-testing'>Animal Testing looks so good that a vaccine is already just days away from the first Href='https://vimarsana.com/news/human-trial'>Human Trials. The new vaccine is being made by nihs partner. We have this beautiful productive collaboration with this biotech company, moderna, and they knew how to make vaccine really fast. He said, as soon as you send us the sequence, we will start manufacturing. And just 66 days after Href='https://vimarsana.com/news/gorge-gao'>Gorge Gao sent out the viral sequence, the Href='https://vimarsana.com/news/nih-moderna-vaccine'>Nih Moderna Vaccine became the first shot against covid to be tested in humans. The first u. S. Trial of a vaccine underway. In seattle Href='https://vimarsana.com/news/science-writer'>Science Writer Href='https://vimarsana.com/news/ian-hayden'>Ian Hayden is one of 45 volunteers for this first Href='https://vimarsana.com/news/human-trial'>Human Trial. So the way i was thinking about it was we, obviously, need this vaccine. We are not going to get one unless healthy people volunteer. And here is a trial in my city. They are looking for people like me. So why not sign up . Massachusetts Href='https://vimarsana.com/news/company-moderna'>Company Moderna are behind the Href='https://vimarsana.com/news/record-speed'>Record Speed Href='https://vimarsana.com/news/clinical-trial'>Clinical Trials. It is Href='https://vimarsana.com/news/wednesday-morning'>Wednesday Morning and i am on my way to receive my first injection. Phase one Href='https://vimarsana.com/news/clinical-trial'>Clinical Trials answer the simple question. Is this Href='https://vimarsana.com/news/vaccine-safe'>Vaccine Safe for a Href='https://vimarsana.com/news/human-being'>Human Being . Is it going to hurt . Have you had Href='https://vimarsana.com/news/flu-shots'>Flu Shots before . Yeah. Shouldnt be any worse than that. The secondary point of them is to oftentimes define a dose that is suitable and safe, but also illicit good Href='https://vimarsana.com/news/immune-response'>Immune Responses. Ian was about to receive the highest dose being tested. The bandaid is going to go on that. That was not bad. Yeah. So a little over 24 hours ago i got my first injection and im feeling fine. I have no symptoms other than an arm thats getting pretty sore. Volunteers are monitored closely as vaccines need to pass the highest standards of Href='https://vimarsana.com/news/safety-'>Safety. 28 days after his first vaccination, ian returned for a booster. I tend in the evening, i started getting chills all of a sudden. I was shivering a little bit. I ended up falling asleep. I woke up though in the middle of the night with a pretty high fever and nauseous and with a pretty bad headache. All the stuff that i had been told to look out for. Muscle aches, things like this that. I just had them all. We got to urgent care at about five in the morning. The Href='https://vimarsana.com/news/lead-doctor'>Lead Doctor on the Href='https://vimarsana.com/news/vaccine-study'>Vaccine Study was already there waiting for us. I spent a lot of time just alone on the bed unsure of what was happening to me. It was scary. It was scary not knowing. Side effects can be a sign that your Href='https://vimarsana.com/news/immune-system'>Immune System is kicking in. But in Href='https://vimarsana.com/news/phase-one'>Phase One, you cant be too careful. If you are planning to immunize Href='https://vimarsana.com/news/7-billion'>7 Billion people on earth who are otherwise healthy, you need to make sure what you are giving them is not going to cause any longterm problems. Ians symptoms were the most extreme of any volunteer in Href='https://vimarsana.com/news/modernas-phase'>Modernas Phase one trial. But two days later he was back home and fully recovered. Its thanks to ian and the other Href='https://vimarsana.com/news/phase-one'>Phase One volunteers that moderna could identify the right vaccine dose. Less than ian received. And the lower dose would now be tested on a much larger group of people. I dont regret signing up for the trial. I am certainly glad that we were able to learn something from my experience and, you know, keep going on this seven. Seven search. Arch. Vaccine dose. In business, its never just another day. Its the big sale, or the big presentation. The day where everything goes right. Or the one where nothing does. With Href='https://vimarsana.com/news/comcast-business'>Comcast Business you get the network that can deliver Href='https://vimarsana.com/news/gig-speeds'>Gig Speeds to the most businesses and advanced cybersecurity to protect every device on it all backed by a dedicated team, 24 7. Every day in business is a big day. Well keep you ready for whats next. Comcast business powering possibilities. Start your day with Href='https://vimarsana.com/news/crest-3d'>Crest 3d white and from mochaccinos to merlot, your smile will always be brilliant. Crest 3d white brilliance. 100 stain removal, 24 Href='https://vimarsana.com/news/hour-stain-resistance'>Hour Stain Resistance to lock in your whitest smile. Crest. The 1 Href='https://vimarsana.com/news/toothpaste-brand'>Toothpaste Brand in america. Someday ill ask you a question that will change me forever. time after time begins to play softly yes. time after time continues to play softly start your someday with a ring from the neil lane collection. Available at kay as march turns to april, the virus is racing ahead of the scientists. The number of cases of Href='https://vimarsana.com/news/coronavirus-worldwide'>Coronavirus Worldwide has now surpassed 1 million. Each day that passes without a vaccine costs thousands of lives. There is no guarantee that anyone will succeed. But more than 80 teams are now in the race. And one of them is a giant even among Href='https://vimarsana.com/news/big-pharma'>Big Pharma giants. Pfizer. Pfizers vast Href='https://vimarsana.com/news/research-and-development'>Research And Development center is in pearl river, Href='https://vimarsana.com/news/new-york'>New York. This is actually a very famous site for vaccines. Over 100 years ago this site was a horse farm. At the time there was a raging epidemic of diphtheria in young children, and a lot of children were dying, and so the new Href='https://vimarsana.com/news/york-health'>York Health commissioner purchased this farm and actually started a business to produce antidiphtheria antitoxin. Antitoxin from the blood of horses. So this is jumbo. 450 gallons over his lifetime to save children. Pfizer grew to be one of the largest companies in the world. And Href='https://vimarsana.com/news/katHrin-jansen'>KatHrin Jansen is head of vaccine Href='https://vimarsana.com/news/research-and-development'>Research And Development. Smuggled out of east germany at 2 years old, she and her family started their life in the west with basically nothing. I had whopping cough as a child, and, you know, you get medication that stops your cough. That is impressive. And so i thought that would be wonderful to work in a field where you could develop those little pills that would make people feel better. Now pfizer is working with a small german company, biontech, and their founder. He called me and said, do you want to partner with us to develop a Href='https://vimarsana.com/news/covid19-vaccine'>Covid19 Vaccine . I said immediately, yes. We did the not have time. We said we better get going on this. So we start Href='https://vimarsana.com/news/ed-work'>Ed Work together before the official contracts were signed. Like moderna, Href='https://vimarsana.com/news/pfizer-and-biontech'>Pfizer And Biontech have placed their entire bet on the brandnew and unproven mrna method. The vaccine approaches that we had lots of experience with, we rejected all of them. This was a bold decision. But mrna had advantages. For one thing, it was flexible. It allows you to adapt very quickly. And perhaps most importantly, it was fast. You can go really at light speed. The only calm in peoples mind. Not so much my mind, that is there has never been a Href='https://vimarsana.com/news/vaccine-produce'>Vaccine Produce with the mrna platform. I guess it was a fear of the unknown. Pfizer has unmatched resources, and they tHrow everything they have behind biontechs innovative design, testing not just one, but four candidate vaccines. This is my home. This is where i usually am most of the time. This huge infrastructure that was tested and proven was at our finger tips, was really unlimited resources. Every Href='https://vimarsana.com/news/human-sample'>Human Sample thats being collected ends up in this machine. So we didnt have to worry about money. We didnt have to worry about is this approach a little cheaper than that approach. All of those considerations were gone. The Href='https://vimarsana.com/news/world-health-organization'>World Health Organization described coronavirus as the defining Href='https://vimarsana.com/news/health-crisis'>Health Crisis of our generation. Big Href='https://vimarsana.com/news/pharma-firepower'>Pharma Firepower makes for rapid progress, but here in brisbane, australia, so, too, can being small and nimble. Will you save that, please, sweetheart . She is all grown up. She can do to herself. A vaccine developed here is the brainchild of dr. Chappelle of the Href='https://vimarsana.com/news/university-of-queensland'>University Of Queensland. He was was one year into a project to develop vaccines for Href='https://vimarsana.com/news/outbreak-diseases'>Outbreak Diseases when the pandemic suddenly made his work much more urgent. It went quickly from practice to, oh, this is the real thing. While the scale is almost impossible to comprehend, we are being warned to prepare for more pain. More than one Href='https://vimarsana.com/news/dozen-staff'>Dozen Staff members have been forced into isolation over fears they may have contracted it was absolutely terrifying watching the numbers come up, you know, watching cases be identified. Brisbane, gulf coast, you know, close to where i live. Seeing graves being dug, so sad. So terrifying. We needed to do all we could. See you later. While Href='https://vimarsana.com/news/moderna-and-pfizer'>Moderna And Pfizer use mrna, oxford has the virus virus, keith is using an older, simpler approach. His vaccine induces an Href='https://vimarsana.com/news/immune-response'>Immune Response by using the entire Href='https://vimarsana.com/news/spike-protein'>Spike Protein. Protein vaccines are the vaccine thats tried and true. The vaccine is protein. Some flu vaccine. So proteins are the vaccines that have been shown to work. It really is the most simple type of vaccine. Its just a small component of the virus and it is combined with a chemical called Href='https://vimarsana.com/news/annage-u-tant'>Annage U Tant which says to your body, look out, that is what is potentially nasty pathogen, make an Href='https://vimarsana.com/news/immune-response'>Immune Response to that. We have got a p. M. You know, they are a fantastic team. They have, you know, the real focus and drive to put in the hours and work together. This year because of the pandemic, so for me and my family, to be a good news to know that the vaccine that you kill is developing prove to be successful coming from africa, i am very much away of Href='https://vimarsana.com/news/infectious-disease'>Infectious Disease. So trying develop vaccines and also this level, even made it more important. Protein vaccines are cheap and easily transportable, making them vital for reaching developing countries. But just like the others, keith faces a key challenge. You see, the Href='https://vimarsana.com/news/spike-protein'>Spike Protein isnt just a stationary protrusion. Its a shape shifter. As in a moving target. The Href='https://vimarsana.com/news/spike-protein'>Spike Protein is highly flexible. It wants to fall apart. It wants to flip into other structures. So its like playing tHreedimensional chess. The shape of the spike before the virus meets our cells is what triggers the strongest Href='https://vimarsana.com/news/antibody-response'>Antibody Response. So any new Href='https://vimarsana.com/news/coronavirus-vaccine'>Coronavirus Vaccine needs a little engineering. To lock it into exactly the right shape. Get it wrong and the Href='https://vimarsana.com/news/vaccine-wont-offer'>Vaccine Wont Offer much protection. At the Href='https://vimarsana.com/news/nih-barney'>Nih Barney had been working with the Href='https://vimarsana.com/news/spike-protein'>Spike Protein for years. This was the Href='https://vimarsana.com/news/spike-protein'>Spike Protein, my hand, these proteins really do change a lot. They go and he thought he knew how to beat it, with a few simple tweaks to keep the spike from changing. Hold it like this and keep it like this. If its not in the right shape, its not going to work. He hoped it would be a key to winning the race. Barneys Href='https://vimarsana.com/news/spike-stabilization-method'>Spike Stabilization Method was adopted by several top teams. Pfizer, Href='https://vimarsana.com/news/johnson-johnson'>Johnson Johnson, sinofi, novavax, but not oxford. And not keith, who decided to go with a different solution. Start splitting the cells. Yeah. What we have got is the molecular clamp that holds it together and allows it to stay 100 in that structure thats present on the surface of the virus. The molecular clamp is based on one of the proteins from hiv. The reason we chose this protein is because its so well understood. Its a highly stable structure. It could be heated to around 90 degrees before it falls apart. Australias hopes are pinned on keith and his young team. Their average age is less than 30. Researchers in queensland have put australia at the forefront of the race to find a Href='https://vimarsana.com/news/coronavirus-vaccine'>Coronavirus Vaccine. Hey. Yeah, im a star. Thanks, mike. Our status around the university is kind of skyrocketed with all the notoriety and everything. So superstar. Thats me. Cameras following you. Feeling stressed in your skin . Not with new Href='https://vimarsana.com/news/olay-retinol-body'>Olay Retinol Body wash. Which improves Href='https://vimarsana.com/news/skin-3x'>Skin 3x better. From dry and stressed, to bright and smooth. So, i can feel my best in my skin. Olay body. Fearless in my skin. Up at 2 00am again . Tonight, Href='https://vimarsana.com/news/try-pure-zzzs'>Try Pure Zzzs all night. Unlike other sleep aids, our extended Href='https://vimarsana.com/news/release-melatonin'>Release Melatonin helps you sleep longer. And longer. Zzzquil pure zzzs all night. Fall asleep. Stay asleep. The full horrifying impact of the first wave of covid19 has been felt worldwide. Mass graves are dug in brazil. Ukraine. Iraq. New york. In one month cases have nearly doubled. And the Href='https://vimarsana.com/news/death-count'>Death Count climbs to over half Href='https://vimarsana.com/news/a-million'>A Million people. I did look at the dashboards in the early days, but as it became apparent how this was going, i didnt do a daily check because that can incapacitate you. That can slow you down. That can put too much of a burden on you. We knew what we had to do and we just have to get on with it. The Href='https://vimarsana.com/news/jenner-institute'>Jenner Institute is named for edward jenner, who developed the worlds first vaccine over 200 years ago. Jenner used crushed Href='https://vimarsana.com/news/cow-pox'>Cow Pox scabs to protect against smallpox. I am wondering about the immunology. It uses hightech tools of the modern lab. The goal is the same. Lots of antibodies. To see if the vaccine is doing what she hopes it is, tess uses a simple test to lack for these antibodies. What you do is you you have a place and you stick on a part of the virus and then you put in some of the samples on top and you are looking to see if there is any antibodies in there that will bind. I am measuring a level within each of the plates. Thats a representation of the amount of antibody we have got in there. Thats specific for a Href='https://vimarsana.com/news/spike-protein'>Spike Protein. So the more yellow that we see in a while, that means the stronger response that weve got. And its going well. They are seeing a lot of yellow. So individuals who have a little bit of a sore arm, they felt a little bit flulike, we got the type of Href='https://vimarsana.com/news/immune-response'>Immune Response we were hoping for. Hi a special, wonderful child. Thank you for months now kizzy has been galloping and the work has paid off. Putting moderna in the lead. Hi she finally gets a moment to breathe and reflect. So good to see you. Hallelujah, god bless you. Yall look so good. Sunday is the day that i watch church and catch up with family. You are still great. Yeah, you are still briefing in god. I am from hillsboro, north carolina. It is a small town. Its very close to the university of north carolina. In summers in Href='https://vimarsana.com/news/high-school'>High School i would intern there in Href='https://vimarsana.com/news/science-labs'>Science Labs and scientists that were around me in that moment struck me as people who i could see myself as. But dreams are just that. Dreams. This was very real, and kizzy felt the pressure to deliver. Weve compared serum from the mrna vaccinated people to people who have recovered from covid and we know that the Href='https://vimarsana.com/news/antibody-response'>Antibody Response is largely, are far better. In other words, subjects getting the vaccine are producing more antibodies than people who actually got the virus and recovered. Thats a very good sign. Jeffs been to the bottom of the ocean. The tops of mountains. And wherever this guy runs off to. A life well lived should continue at home. With home instead care, older adults can stay home, safe, and happy. Home instead. To us, its personal. Maybe i didnt love you quite as often as i could have were delivering for the earth. By investing in more electric vehicles, reusable packaging, and carbon capture research. Making earth our priority. I thought id seen it all. i brought in ensure max protein, with thirty grams of protein. 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Zyrtec starts working hard at hour one and works twice as hard when you take it again the next day. Zyrtec. Muddle no more. And try zyrtecd for proven relief of your allergies, Href='https://vimarsana.com/news/sinus-pressure'>Sinus Pressure and congestion. Australias government and new Href='https://vimarsana.com/news/pharma-partner'>Pharma Partner are spending millions to Href='https://vimarsana.com/news/manufacturer-it'>Manufacturer It at Href='https://vimarsana.com/news/mass-scale'>Mass Scale and theyve begun Href='https://vimarsana.com/news/phase-one'>Phase One Href='https://vimarsana.com/news/human-trial'>Human Trials. 30 seconds. When youre ready. All right. Around halfway tHrough the Href='https://vimarsana.com/news/phase-one'>Phase One trial now. And what weve seen is the incredible Href='https://vimarsana.com/news/safety-'>Safety of this product. You must be joel. We really appreciate you being here. So well be analyzing that to see how Href='https://vimarsana.com/news/it-work'>It Works. Now Href='https://vimarsana.com/news/Href='https://vimarsana.com/news/safety-'>Safety-review'>Safety Review committees have been relatively boring. Theres been nothing to discuss, which is fantastic for us. Their rapid are progress has made them headline news. How you feel about that . Oh, i like that movie . For the team, we are feeling on a high, but i am literally exhausted. I havent had a good Href='https://vimarsana.com/news/nights-sleep'>Nights Sleep for i dont know when. Vaccine development has never been done at this speed before. What keeps you up at might is have i made a mistake, what will we miss and get wrong that will cost us a week and will cost lives. You know, its just constantly running tHrough your head. Some early Href='https://vimarsana.com/news/trial-results'>Trial Results are encouraging. But no approach has a clear advantage, not yet. Will the winner be a Href='https://vimarsana.com/news/protein-vaccine'>Protein Vaccine like the shot from with queens lapd, now keeping up with biotech giant csl, or Href='https://vimarsana.com/news/novovax-which'>Novovax Which was also protein based, or a Href='https://vimarsana.com/news/vector-vaccine'>Vector Vaccine like oxfords and their new partner astrazeneca, or Href='https://vimarsana.com/news/johnson-johnson'>Johnson Johnson, which also shows promising results in early trials or the russian vaccine called sputnik. The Href='https://vimarsana.com/news/pfizer-and-moderna'>Pfizer And Moderna ones are moving fast as well. Then theres china. [ speaking foreign language ] in a Href='https://vimarsana.com/news/highlevel-bio-Href='https://vimarsana.com/news/safety-'>Safety'>Highlevel Bio Safety Href='https://vimarsana.com/news/facility-theyve'>Facility Theyve be leading chinas entire vaccine strategy, including the oldest method of all. Using the entire killed virus. [ speaking foreign language ] the first step was to grow a large quantity of the deadly virus in their lab. [ speaking foreign language ] george Href='https://vimarsana.com/news/ga-os'>Ga Os cook is here an it was her task to select Href='https://vimarsana.com/news/virus-sample'>Virus Sample to become the Href='https://vimarsana.com/news/seed-stock'>Seed Stock for all chinas inactive vaccines. [ speaking foreign language ] her goal, a strain that closely matches the virus thats spreading tHrough the population. The closer the match, the better the protection. For her, that makes sequencing the Href='https://vimarsana.com/news/genetic-code'>Genetic Code grown in the lab for the vaccine over and over again. [ speaking foreign language ] we know its going to take many forms of energy to meet the worlds needs while creating a Href='https://vimarsana.com/news/cleaner-future'>Cleaner Future for all. At chevron, were lowering the carbon Href='https://vimarsana.com/news/emissions-intensity'>Emissions Intensity of our operations, investing in lowercarbon technologies, and exploring renewable fuels of the future. We work hard to care for the homes we love. But its only human. To protect the one we share. [sfx psst psst] allergies dont have to be scary. The homes we love. Spraying flonase daily stops your body from overreacting to allergens all season long. Psst psst all good life. Doesnt stop for diabetes. Be ready for every moment, with glucerna. Its the number one doctor recommended brand that is scientifically designed to help manage your blood sugar. Live every moment. Glucerna. Is scientifically designed to help manage your blood sugar. Look, if your Href='https://vimarsana.com/news/wireless-carrier'>Wireless Carrier was a guy youd leave him tomorrow. Not very flexible. Not great at saving. You deserve better. Xfinity mobile. Now they have unlimited for just 30 a month. 30. And theyre number one in customer satisfaction. His number. Delete it. Im deleting it. So, break free from the big tHree. Xfinity internet customers, switch to Href='https://vimarsana.com/news/xfinity-mobile'>Xfinity Mobile and get unlimited with 5g included for 30 on the nations fastest, most reliable network. The whole pandemic was a wakeup call. Even though there is no guarantee any of this will work, in china and around the world, factories are preparing to make the products on an unprecedented scale. There are sevenplus billion people in the world and there is going to be a race to vaccinate everybody, we need billions of doses. We have a big task immunizing the entire world. In bergen county, new jersey, this suburban home has become the epicenter of a global vaccine manufacturing operation, overseeing more than 30 factories. Like so many people across the world, Href='https://vimarsana.com/news/pfizers-president'>Pfizers President of global supply, mike mcdermott, is working from home. Initially, it was more problems problem, or Href='https://vimarsana.com/news/catherines-science'>Catherines Science come to bear. But once we get the notion, you might want to scale up your manufacturing facilities now. Then i started to panic. The thing about a pandemic, No One is immune. For mike, it was a fight for the world and for his family. This is deeply personal. One has cystic Href='https://vimarsana.com/news/fibrosis-and-one'>Fibrosis And One has as ma. Were going to keep pushing to make sure we bring this vaccine as soon as. Remember, pfizer has four different designs for their rnma vaccine. I had no idea. It was a bit like getting ready for dessert and were not sure are we going to make cookies or make a cake. I started buying materials, and today were looking to run tHrough the week, i guess. Oh, yeah. 24 7. Tip ypically i dont start ul later. I started this Href='https://vimarsana.com/news/manufacturing-work'>Manufacturing Work with my team before we even started the Href='https://vimarsana.com/news/clinical-trial'>Clinical Trial. It was a different process for us. In michigan, pfizers largest manufacturing site. Here, Href='https://vimarsana.com/news/pat-mcavoy'>Pat Mcavoy is director of operations for Href='https://vimarsana.com/news/covid-vaccine'>Covid Vaccine production. This hallways a little over a quarterback of a mile long. Every system is being put tHrough the paces. Youre looking into our newest Href='https://vimarsana.com/news/aseptic-line'>Aseptic Line and its a 100 dedicated to the Href='https://vimarsana.com/news/covid-vaccine'>Covid Vaccine. This is the automated visual inspection. Theres 15 cameras that are taking dozens of pictures as the viles come tHrough and theyre looking for any defects. The final step is freezing. So what we do is that we freeze that mrna and it stabilizes it. It needs to be stored at Href='https://vimarsana.com/news/minus-70'>Minus 70 degrees celsius. Thats 50 degrees colder than a standard household freezer. Every two weeks well bring in tHree truckloads. We currently have 200 freezers on site, another 60 showing up today. These freezers inject an immense amount of energy, so we put in six Href='https://vimarsana.com/news/air-handling'>Air Handling units just to remove the Href='https://vimarsana.com/news/heat-load'>Heat Load coming off of these freezers. Nothing taken for granted, not when it comes to getting the vaccine where it needs to go. Well then pack these into a shipper with Href='https://vimarsana.com/news/dry-ice'>Dry Ice that will actually keep the product frozen at Href='https://vimarsana.com/news/minus-70'>Minus 70 for ten days. The box well use for the Href='https://vimarsana.com/news/tenday-shipper'>Tenday Shipper is actually right here. This will be filled with Href='https://vimarsana.com/news/dry-ice'>Dry Ice. Of course, this all requires a mountain of Href='https://vimarsana.com/news/dry-ice'>Dry Ice, so much so that mike ordered up his own Href='https://vimarsana.com/news/small-factory'>Small Factory to make it. It includes a Href='https://vimarsana.com/news/gps-tracker'>Gps Tracker as well as a temperature sensor. The team came forward with the solution. It blew me away that this thing could move the product for ten days without plugging it in. We did all our activities in parallel at risk, investing in materials before we had any idea if the product would work. The economic pressure is strong in many countries. The global rate of infection continues to rise. In the last 24 Href='https://vimarsana.com/news/hours-brazil'>Hours Brazil has reached Href='https://vimarsana.com/news/two-million'>Two Million cases, india, 100 million. Yesterday saw the highest total daily doses, over 73,000 in the u. S. By late july under intense pressure, the fastest moving teams begin publishing positive results from their Href='https://vimarsana.com/news/phase-one'>Phase One Href='https://vimarsana.com/news/human-trial'>Human Trials. Biotech Href='https://vimarsana.com/news/company-moderna'>Company Moderna reporting promising results told. The new data from the Href='https://vimarsana.com/news/phase-one'>Phase One trial shows the drug appears to be save and triggers a robust Href='https://vimarsana.com/news/immune-response'>Immune Response. Scientists say the vaccine theyre developing appears safe. The Href='https://vimarsana.com/news/oxford-vaccine'>Oxford Vaccine does show some promise. But as the Href='https://vimarsana.com/news/virus-races'>Virus Races ahead, the pressure weighs heavy on Href='https://vimarsana.com/news/pfizers-head'>Pfizers Head of vaccine research, catherine jansen. Its devastating to see that we cant seem to get this pandemic under control. What keeps me sane is walking in the park in the morning and listening to the birds sing. What helps me to get out of the Href='https://vimarsana.com/news/thinking-mode'>Thinking Mode of, you know, my work, and really clear my mind. At almost the exact same time as moderna and oxford, pfizer, too, releases positive early Href='https://vimarsana.com/news/human-trial'>Human Trial results, and catherine finally selects one of pfizers four Href='https://vimarsana.com/news/mrna-vaccine'>Mrna Vaccines to test on a bigger stage. The Href='https://vimarsana.com/news/giant-pfizer'>Giant Pfizer is reporting encouraging early data on a Href='https://vimarsana.com/news/coronavirus-vaccine'>Coronavirus Vaccine candidate that is im very surprised to see them come out this early. They must feel a level of confidence that is extraordinary. It was pretty spectacular to see those data. But again, i cannot be too elated, because the biggest hurdle now that we have to overcome, we now have to do with the hard part, does Href='https://vimarsana.com/news/it-work'>It Work. And if Href='https://vimarsana.com/news/it-work'>It Works, how well does Href='https://vimarsana.com/news/it-work'>It Work . Hey lily, i need a new Href='https://vimarsana.com/news/wireless-plan'>Wireless Plan for my business, but all my employees need something different. Oh, we can help with that. Okay, imagine this. Your mover, rob, hes on the scene and needs a plan with a mobile hotspot. We cut to downtown, your Href='https://vimarsana.com/news/sales-rep-lisa'>Sales Rep Lisa has to send some files, asap so basically i can pick the right plan for each employee. Yeah i shouldve just led with that. With at t business. You can pick the best plan for each employee and only pay for the features they need. Are you managing your diabetes. Using fingersticks . 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Pfizer now moves to Href='https://vimarsana.com/news/phase-tHree-trial'>Phase THree Trials, involving Href='https://vimarsana.com/news/tens-of-thousands'>Tens Of Thousands of people. Usually after early trials with just a handful of volunteers, Href='https://vimarsana.com/news/the-next-step'>The Next Step would be phase two with a few hundred. But again, given the urgency, these steps are all now happening at once. We care for the quality looking carefully at Href='https://vimarsana.com/news/safety-'>Safety, all of this was normal routine procedure. The process never changed. Its how we compressed time and how we did parallel work. Thats really what changed. To a truth, the huge numbers necessary, pfizer has dozens of Href='https://vimarsana.com/news/phase-tHree-trial'>Phase THree Trial sites all over the world and Href='https://vimarsana.com/news/new-york'>New York city is home to one of the largest. Mount sinai hospital. How well does Href='https://vimarsana.com/news/it-work'>It Work . At some point, we have 6 . This is just like starting all over again. Do you see it . Oh, definitely. I will say that all the participate amounts are really hopeful that this will be the vaccine that works. Judy is one of the trial doctors. Its devastating again to see the increase thats happening in Href='https://vimarsana.com/news/new-york'>New York city. In any Href='https://vimarsana.com/news/phase-tHree-trial'>Phase THree Trial, the participants are divided into two groups. One will be given a vaccine. The other a placebo. Its a crazy morning. We have 11 people coming back for their second vaccine and then we have several people coming in now for their initial consent and they, too, would get vaccinated. It takes 45 minutes to thaw and prepare each dose, making sure so hide any clue of whats inside. This is vital, because the trial is blind. The product that they receive is packaged to maintain that blind. Neither those administering the vaccine nor the volunteers receiving it know if thats sa run buildings carry the vaccine or the placebo. Even if theyre preparing placebo, they have to take that 45 minutes of time for that to remain blind to whats going on. Im in a higHrisk group, so i wanted to be proactive. I hope i get the vaccine, obviously. If i get the placebo, i get the placebo. Its still information that theyre using. All the way down and then to the right. Thank you. What we dont want is people assuming that they actually got the vaccine and that Href='https://vimarsana.com/news/it-work'>It Works, so that they let their guard down because they believe theyre protected. We absolutely do not know if this vaccine is protective at this time, so thats very critical that people understand this. The only way to discover the vaccine really works will be to see how many of the vaccinated volunteers get sick from covid19 compared to those in the placebo group. And that will take time. We need to register Href='https://vimarsana.com/news/a-million'>A Million more volunteers to complete the studies and possibly get a safe and effective vaccine to hundreds of millions of americans. The Href='https://vimarsana.com/news/vaccine-trial'>Vaccine Trial needs americans of every race, location, and medical condition to help in one of the most important endeavors of our lifetime. Recruiting trial participants on this scale and at this speed has never been attempted before. In september, moderna, who began their Href='https://vimarsana.com/news/phase-tHree-trial'>Phase THree Trial on the exact same day as pfizer, revealed theyve hit a problem. Covid Href='https://vimarsana.com/news/vaccine-trial'>Vaccine Trials did not include many people of color. The company is slowing enrollment in ordered to assure participation from minority groups. Unfortunately those rumors and false rumors get out there. The Href='https://vimarsana.com/news/tuskegee-experiment'>Tuskegee Experiment and many africanamericans still have that in their minds as well. In that notorious study, doctors help treatment with black patients with syphilis for more than four decades to see how the disease would progress. Ch but its not just that. Terrible as it was, its part of a long history of unequal care. Africanamerican people, the hesitancy comes from a history of medical injustice that fueled miss trust, that is just undeniable. For kidsy, making this work moves a successful vaccine in the lab into a trusted vaccine in peoples minds and hearts. The one thing thats important around Href='https://vimarsana.com/news/vaccine-hesitancy'>Vaccine Hesitancy is that i think black people have never actually been asked to be in trials before, and its i think its a Href='https://vimarsana.com/news/learning-experience'>Learning Experience for everyone. Like i mean, to answer your Href='https://vimarsana.com/news/question-and-trust'>Question And Trust is stripped from people, rebuilding it is brick by brick, right . You have to really speak to targeted audiences and you have to speak with a voice that people do trust and from a perspective that they understand. Its the way we think about science. The doctor said to me that for every 1,000 people that we inform well enough that they choose to get vaccinated, thats ten lives that are saved. And when youre in a webinar with sometimes 10,000 people, the numbers add up. You either do it or people die. Started now. Were starting to see familiar and troubling case patterns emerge both here and abroad. This is the Href='https://vimarsana.com/news/death-toll'>Death Toll in the u. S. Tops 200,000, the highest in the world. The death rate, crazy. Scared the hell out of me. In boston, Href='https://vimarsana.com/news/60yearold-anthony'>60yearold Anthony shivers is all too aware of the fears that surround the investigators and the vaccine. Find this sucker. Im going tHrough my phone. Im on facebook and i see people say dont take the shot because the shot will kill you. Imagine that. When i hear things like this coming from black people, that really concerns me, because this is a disease. This is not a me disease. This is a we disease. This is a disease that affects everybody. You understand what im saying . Despite the urgent need for a vaccine, moderna deliberately slows down the trial to focus on recruiting more people of color. Moderna said its telling Href='https://vimarsana.com/news/clinical-trial'>Clinical Trial sites that have not enrolled enough in these communities to do better. I heard they need blacks to get involved with the moderna trials and a lot of blacks werent signing up. In order to solve a problem, you got to be a part of the solution. I went to the hospital. I got my first shot. And it was ok. I got other friends that have taken the shots, so im really happy about it. Look at me. You know, aint nothing wrong with me. I had the ability to talk to an Href='https://vimarsana.com/news/anthony-fauci'>Anthony Fauci or a president and then also i have explained the vaccine to my cousin, who is in prison, who i talk to often, and he gets it, too. What she knows is that those most hesitant are oftentimes those most at risk for being Href='https://vimarsana.com/news/hospital-liesed'>Hospital Liesed and dying. Im happy to be a connection to people to the extremely confusing system of how vaccines are made and how vaccines are approved and how the trials work, representing like my community in a way. My purpose for this is resonating with my community. A big deal for me. [sfx psst psst] allergies dont have to be scary. Spraying flonase daily stops your body from overreacting to allergens all season long. 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Well, an internet connections a good start. But kids also need computers. And sometimes the hardest thing about homework is finding a place to do it. So why not hook Href='https://vimarsana.com/news/community-centers'>Community Centers up with wifi . For kids like us, and all the amazing things were gonna learn. Over the next 10 years, comcast is committing Href='https://vimarsana.com/news/1-billion'>1 Billion to reach Href='https://vimarsana.com/news/50-million'>50 Million lowincome americans with the tools and resources they need to be ready for anything. I hope youre ready. cause we are. Moderna Href='https://vimarsana.com/news/ace-delay'>Ace Delay to recruit more black volunteers looks like fighter is best placed in the race to get results first. This race is just kicking off in the pivotal trials for potential approval if these vaccines do well. Oxford, not far behind. While queens Href='https://vimarsana.com/news/lapds-vaccine'>Lapds Vaccine is planning to embark on its Href='https://vimarsana.com/news/mass-phase'>Mass Phase tHree trial. By summer it looks promising that the australian government has bought doses of the vaccine, enough to vaccinate the entire population twice. The vaccine was looking perfect. Weve got good efficacy data from animals. Weve got manufacture. Safety is looking fantastic, and now weve got a problem that we need to work tHrough. This is diagnostic with a participant whos received our vaccine. What were looking for here is this band showing up. Very faint there. That would be considered a positive or a false positive. Remember the molecular clamp in the vaccine, well, that uses a tiny flag of Href='https://vimarsana.com/news/hiv-protein'>Hiv Protein and as a result, some of those receiving the vaccine are not only testing positive for antibodies to covid but also antibodies to hiv. Weve got this other version here with a different company. This version shows up negative. To be clear, the volunteers have not been infected with hiv, but some of the tests come back positive and keith now needs to know which of these tests will register those false positive results. Its a strange problem. But a problem nonetheless. I dont think its ok for us on the way around. We just need to work it out. Vaccines remain the best hope to stem the rising tide of new cases. Vaccines that may ultimately be used by nearly every man, woman, and child on the planet. Chinas government wants to supply vaccines to the world. And that puts enormous pressure on Href='https://vimarsana.com/news/george-gao'>George Gao. And on rue, his chief lieutenant. [ speaking foreign language ] for all the teams, the pressure is only growing greater. Especially as england goes into its second national Href='https://vimarsana.com/news/lockdown-and-europe'>Lockdown And Europe and america suffer tHrough a devastating second wave. The president ial election in november is creating a huge incentive for Href='https://vimarsana.com/news/president-trump'>President Trump to get a vaccine out before then. Its going to be done in a short period of time. Could even have it during the month of ok. Which puts the scientists in an awkward position. The implication that they cut corners for speed could undermine public confidence. There was a lot of political pressure on the Href='https://vimarsana.com/news/vaccine-manufacturers'>Vaccine Manufacturers to do things faster. This is a distraction. Its not helpful and you block it out and you just focus on the task. Up at 2 00am again . Tonight, Href='https://vimarsana.com/news/try-pure-zzzs'>Try Pure Zzzs all night. 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But No One, not even the scientists know when phase two trials will yield results. They wait for a predetermined number of people to get sick and hope that the vast majority of the afflicted are mr. The placebo group. Since trials are blind, an independent Href='https://vimarsana.com/news/monitoring-board'>Monitoring Board has to track the cases and flag when the numbers are high enough to review. Each new Href='https://vimarsana.com/news/covid-case'>Covid Case is a step closer to knowing if their vaccine is going to work. All the teams, its an anxious wait. Take a deep breath in. And exhale out. I think that part of my Href='https://vimarsana.com/news/anxiety-management'>Anxiety Management has really helped me to see things for what i can control versus what i cannot. So preclinical data, i could control it. But when you give 30,000 people a vaccine and then allow them to go out into the world, theres really nothing you can do at that point. No. Its what i always say, my least favorite games. Its a waiting game. When you work tHrough the problems and youre working hard and you work with your Href='https://vimarsana.com/news/team-and-everybody'>Team And Everybody is working in the same direction. You dont think about this. But all of a sudden in this moment of what can the result be, but theres nothing you can do. Im out of it. You just feel powerless. Its out of your hands. You do everything, you put it all together and now this is a moment of truth and theres nothing you can do about it. On november 9th, nine months and 30 days after the race for a vaccine began, an answer. And its catherine out walking who receives the call from pfizers ceo albert. He called and said catherine, i have to tell you, we are allowed to say that your vaccine is over 90 efficacy. Following the news that a vaccine against Coronavirus Has proved 90 effective. I was just out of my mind, just laughing and dancing around. It is a great day for science. It is a great day for humanity. Of 170 volunteers who fell sick with covid19 during the trial, nearly all, 162 of them, were in the placebo group. It is Href='https://vimarsana.com/news/pfizer-and-catherine'>Pfizer And Catherine that have won the race. Were talk about for the first time ever, people outside of the Href='https://vimarsana.com/news/clinical-trial'>Clinical Trial receiving a Href='https://vimarsana.com/news/coronavirus-vaccine'>Coronavirus Vaccine before cHristmas, so its pretty incredible pace here. This immense belief that, yes, now, we will fight this thing and we will get the pandemic under cHrome. Its just like its an amazing feeling. I mean, thats all ki say. Exactly one week later at 6 00 a. M. , barney makes a call. Well, good morning. Good morning. Hows it going . I am calling you because we got Href='https://vimarsana.com/news/results-yesterday'>Results Yesterday and theyre going to be announced in just a few minutes, so by press release. Ok. So what did they say . Well, there was 95 cases, and 90 of them were in the placebo group, five were vaccinations. Yeah. Looks like its going to work. Mrna, the newest technology that many doubted has brought success beyond the wildest hopes. Severe disease, which is even better news. That is amazing news. Wow. I dont even know what to say. But as the first two groups crossed the Href='https://vimarsana.com/news/finish-line'>Finish Line and relished the tHrill of victory, in australia, the agony of defeat. Just one day after Href='https://vimarsana.com/news/kids-kizzie-s'>Kids Kizzie S of the mod erma trial, the information for keith is crushing. Got some news that came Out Of The Blue that basically weve just had our funding cut. All due to this hiv diagnostic problem. Pretty devastating. The advice that we have received is that the Href='https://vimarsana.com/news/university-of-queensland'>University Of Queensland will not be able to proceed based on the scientific advice and that well no longer feature as part of australias vaccine plan. Theres a lot of people that now im going to have to tell who are going to be gutted, devastated. A lot of the people from our team are people that come from, you know, africa, sri lanka. They wanted to be part of giving something to the world, giving back to their communities and all those communities. The vaccine is safe. Have hundreds of millions of doses in the freezer ready to go. We can ship it everywhere in the fridge at Href='https://vimarsana.com/news/minus-70'>Minus 70, mooiinus 80 degrees. Theres one problem. Its the diagnostics of hiv. Keiths vaccine will not move forward but its moments like this when trust in science is not eroded but instead fortified, honesty, even when the news is not good. I think transparency from Href='https://vimarsana.com/news/vaccine-developers'>Vaccine Developers is of crucial importance and i hope that us being completely transparent and up front about these results is public confidence in vaccines overall. I think what weve achieved this year is remarkable. We can hold our Heads High and, you know, i think its a very sad time but also were very, very proud of what weve achieved. [ applause ] as a scientist, we have a lot of different jobs. We have a job to make a vaccine. But we also have the job to train people, to educate people, and to be able to to step back and say look, we did all we could. This is other vaccines that are also looking great, so take those. Thats an important part of our job as well. Its not all about making a vaccine and getting to the Href='https://vimarsana.com/news/finish-line'>Finish Line. [sneezes] hey allergy muddlers. [sneezes] are your sneezes putting your friends in awkward positions . [sneezes] stick with zyrtec. Zyrtec starts working hard at hour one and works twice as hard when you take it again the next day. Zyrtec. Muddle no more. And try zyrtecd for proven relief of your allergies, Href='https://vimarsana.com/news/sinus-pressure'>Sinus Pressure and congestion. In business, its never just another day. And its the big sale, Oren Re the big presentation. , the day where everything goes right. Or the one where nothing does. With Href='https://vimarsana.com/news/comcast-business'>Comcast Business you get the network that can deliver Href='https://vimarsana.com/news/gig-speeds'>Gig Speeds to the most businesses and advanced cybersecurity to protect every device on it all backed by a dedicated team, 24 7. Every day in business is a big day. Well keep you ready for whats next. Comcast business powering possibilities. Maybe i didnt love you quite as often as i could have were delivering for the earth. By investing in more electric vehicles, reusable packaging, and carbon capture research. Making earth our priority. I thought id seen it all. among my patients i often see them have Href='https://vimarsana.com/news/teeth-sensitivity'>Teeth Sensitivity as well as gum issues. I thought id seen it all. Does it worry me . Absolutely. Sensodyne Href='https://vimarsana.com/news/sensitivity-and-gum'>Sensitivity And Gum gives us a dual Href='https://vimarsana.com/news/action-effect'>Action Effect that really takes care of both our Href='https://vimarsana.com/news/teeth-sensitivity'>Teeth Sensitivity as well as our gum issues. Theres no question its something that i would recommend. With the virus still spreading rapidly around the world, not one or two but many vaccines are needed to protect a global population of almost Eight Billion people. And for most of the world, those vaccines need to be cheap and easy to store. [ speaking foreign language ] countries like brazil, chile, turkey, and indonesia, are all using the chinese vaccines, even though studies arent complete and the interim results are all over the map. [ speaking foreign language ] in oxford, the team gathers to watch the announcement of their results. The vaccine developed by scientists at oxford is set to transform the battle against krierd around the world. But the Href='https://vimarsana.com/news/trial-results'>Trial Results, theyre complicated. Different groups of volunteers, different doses and schedules, and different efficacy numbers. The average, 70 . Thats a ways below Href='https://vimarsana.com/news/pfizer-and-moderna'>Pfizer And Moderna. On the other hand, its another vaccine that works. And theres a key point within the data. Hyka those other two vaccines, the Href='https://vimarsana.com/news/oxford-astrazeneca-shot'>Oxford Astrazeneca Shot does very well when it comes to preventing the most severe infections. These vaccines are stopping severe disease. Theyre stopping you going into hospital. If the vaccine stops you from dying, its a Href='https://vimarsana.com/news/vaccine-id'>Vaccine Id put in my arm. I got the results, super proud and then get on it with it again. Tired but really excited. Yeah. Because i think if we think about it too much or resume nate, it can overwhelm and we still have a lot to do. We shouldnt keep concentrating on one vaccine being better than another. We should be happy that we have so many vaccines. Because without a large number were never going to be able to vaccinate the whole world. You can intervene with, say, a 40 effective vaccine four months before you can intervene with an 80 effective vaccine, you save more lives with the 40 effective vaccine thats delivered four months earlier. Being fast in an Href='https://vimarsana.com/news/outbreak-setting'>Outbreak Setting in some ways is more important than being perfect. The sprint to develop vaccines has been a success. But theres still a major hurdle to overcome. Getting the shots into arms. As the first to cross the Href='https://vimarsana.com/news/finish-line'>Finish Line, all eyes are on pfizers factories and shipping operation. And on mike. There is a scramble to finish up all the final paperwork, all the work we needed to do to actually ship these doses. With vaccines packed and ready to go, on december 2nd, the uk becomes the first country in the world to approve Href='https://vimarsana.com/news/pfizers-vaccine'>Pfizers Vaccine for use outside a Href='https://vimarsana.com/news/clinical-trial'>Clinical Trial. Its called vday. Just like that, the race for a vaccine has become the race for vaccination. 90yearold Margaret Keenan will go down in history. Shes become the first person in the world to receive the Href='https://vimarsana.com/news/pfizer-vaccine'>Pfizer Vaccine against covid19. [ applause ] i dont hydrate like everyone else. Because im not everyone else. They drink what theyre told to drink. I drink what helps Me Rehydrate and recover pedialyte® sport. Because Href='https://vimarsana.com/news/it-work'>It Works. And so do i. Hydration beyond the hype. So whats going on . Hydration beyond the hype. [dog] im a talking dog. The other issue. [dog] oh. Im scratching like crazy. Youve got some allergic itch with skin inflammation. Apoquel can work on that itch in as little as 4 hours, whether its a new or cHronic problem. And apoquels treated over 9 Million dogs. [dog] nice. And. The talking Href='https://vimarsana.com/news/dog-thing'>Dog Thing . Is it bothering you . No. Itching like a dog is bothering me. Until dogs can speak for themselves, you have to. When allergic itch is a problem, ask for apoquel. Apoquel is for the control of itch associated with allergic dermatitis and the control of Atopic Dermatitis in dogs. Do not use apoquel in dogs less than 12 months old or those with serious infections. Apoquel may increase the chances of developing serious infections and may cause existing parasitic Skin Infestations or preexisting cancers to worsen. New neoplasias were observed in clinical studies and postapproval. Most common Href='https://vimarsana.com/news/side-effects'>Side Effects are vomiting and diarrhea. Feeling better . [dog] im speechless. [dog] thanks for the apoquel. Thats what friends are for. Ask your veterinarian for apoquel. Next to you, apoquel is a dogs best friend. On the first anniversary of Href='https://vimarsana.com/news/george-gao'>George Gao publishing the sequence of the Href='https://vimarsana.com/news/novel-coronavirus'>Novel Coronavirus it is killing people faster than ever. By now there are several vaccines in use. Pfizer, moderna, astrazeneca, the chinese and russian va vaccines. And the newly approved Href='https://vimarsana.com/news/johnson-johnson'>Johnson Johnson shot. But it will take years to protect the entire global population. And scientists will need to stay vigilant for Href='https://vimarsana.com/news/safety-'>Safety. Some rare cases of Blood Clots have been associated with the Href='https://vimarsana.com/news/j-j'>J J and Href='https://vimarsana.com/news/oxford-vaccine'>Oxford Vaccines. But most countries have determined that the risk from the virus is far greater than the minuscule risk of these clots. The bigger challenge is that the virus itself is changing. The Href='https://vimarsana.com/news/new-variant'>New Variant is highly concerning. It appears to have mutated further. The new form of the virus is potentially far more infectious. It is not yet okay. If youre not careful and the virus is finding a way to escape immune protection, we could as well start all over again. Viruses evolve. Weve known that for years. They change. They mutate. Most mutations are harmless and dont change the effectiveness of the vaccines. But the more the virus spreads the higher the odds that something dangerous will emerge. New variant of the virus is spreading quickly. Theyre more transmissible. A few of the variants have mutations in the Href='https://vimarsana.com/news/spike-protein'>Spike Protein that subtly change its shape. Antibodies that neutralize the original strain of the virus simply dont bind as well. The race has changed. Its now the vaccine against the variants. We have to put systems in place, Early Warning Systems that allow us to identify a variant that may truly be of concern. Any new vaccine takes time to develop. But mrna, this breaktHrough technology, makes our defenses more nimble than ever. The beauty of the Href='https://vimarsana.com/news/mrna-technology'>Mrna Technology is that were able to quickly modify the beginning of the process if there was a Href='https://vimarsana.com/news/new-variant'>New Variant detected and actually put that into our existing supply chain. We think the process to modify and actually produce product could be done in tHree months. The Href='https://vimarsana.com/news/covid19-pandemic'>Covid19 Pandemic is still exacting an unbearable human cost. But thanks to the efforts of a few scientists were being spared an even worse fate. A moonshot of science. With their backs up against the wall, the genius, the ingenuity, and perhaps most of all the will of the Human Spirit came tHrough. Like it has before. My dads an electrical and mechanical engineer. He worked for nasa when i was a young boy. And i honestly always wondered if i would be involved in something like the Href='https://vimarsana.com/news/space-program'>Space Program in the 60s. And actually, the first day that we shipped the vaccine in the u. S. I had that very moment. The most pressure that was put on us, we put on ourselves. We were under the microscope. But thats okay because science is pretty straightforward. You are always most successful if you make your decision based on scientific data. That will get you over the Href='https://vimarsana.com/news/finish-line'>Finish Line always faster. It truly is amazing to see how many people are interested in a virus that nobody cared about 16 months ago. Heavenly father, we thank you for this time and this place hopefully, it opens up the eyes of young people who are deciding right now im going to be a viral immunologist and make vaccines and thats what i want to do when i grow up. This looks good. Youre barney graham. Yes, i am. Any questions regarding the vaccine . No. Im ready to go. How was that . Beautiful. If you want to head to the observation area, well keep an eye on you for 15 minutes. Sometimes i just like to go over to the cafeteria on the Href='https://vimarsana.com/news/nih-campus'>Nih Campus where a lot of these vaccinations are done and just sit there and watch people be vaccinated. Kizzy, no longer the junior scientist, will now be running her own lab at harvard. Oh, my god, Href='https://vimarsana.com/news/i-cant'>I Cant believe this is happening. Where shell look to develop a universal Href='https://vimarsana.com/news/coronavirus-vaccine'>Coronavirus Vaccine. Slow and steady wins the race. The progress is often slow. Theres failures. But if you keep chugging along, eventually youll get to the point where it pays off. And i think thats what were seeing now. In a year when so much went wrong this one thing went right. And when the story of this pandemic is told it will celebrate the gift of these vaccines and the superheroes who raced to bring them to us at such remarkable speed. [ cheers and applause ]. Its not necessary to salute, sir. Just your hand over your heart is enough when we come out. He was funny. He had this aura about him. May the Href='https://vimarsana.com/news/killer-whale-relieve'>Killer Whale Relieve himself on your carpets. Hes the king of late night. But he was still a loner. It never occurred to me that there would be other talk shows. Ladies and gentlemen, the Href='https://vimarsana.com/news/reverend-dr.'>Reverend Dr. Martin luther king. The tension was wonderful. Are you really all truly idiots or is it me . But it was going to be shocking. The super bass omatic 76. Got to get the