We start this hour with what experts are calling a potential game changer in the treatment of skin cancer. The worlds first personalised vaccine for melanoma the deadliest form of skin cancer has begun being tested in britain. Some other countries, including australia, are also trying it on patients. The treatment, which uses the same mrna technology as some covid jabs, works by telling the body to hunt down cancer cells and prevent them from coming back. Researchers say the jab also has the potential to stop lung, bladder and kidney cancers. More details from our health correspondent, sophie hutchinson. Steve young, one of the first nhs patients to take part in the trial for whats hoped will be a Game Changing treatment. Its for melanoma the deadliest of all the skin cancers and it aims to help those at the highest risk of a recurrence. Steve was given the experimental treatment at University College hospital in london. He had a melanoma removed from his scalp last summer. He told us the trial is his best chance of keeping cancer free. I feel. 0k. Someone told me ive got survivor syndrome because i actually feel guilty i feel guilty that im completely fine and yet im getting all this attention and im. You know, i get to have a scan and an mri every three months when i know that people are waiting such a long time. And i. I genuinely feel kind of awful about that. But. Ijust really hope that whats happening with the trial and the results they get are going to be good news, and its going to go on to do amazing things. The Personalised Treatment works by identifying proteins unique to each persons cancer, and then uses the same technology which created some covid vaccines called mrna to prime the Immune System to attack the cells. Its being used in combination with another cancer drug, and previous results suggest together it almost halved the risk of recurrence or death after three years. Its a very specific treatment, highly personalised to each individuals tumour, and its a really exciting way of hopefully turning the patients own Immune System against their cancer. And it looks like it could be a really effective therapeutic approach. This trial will really prove thats the case or not. This is an international trial. Uk doctors are hoping to recruit at least 70 patients across centres including london, manchester, edinburgh and leeds. Sophie hutchinson, bbc news. Its another big day at the post Office Inquiry a former executive accused of covering up knowledge of the faulty it system is giving evidence for a second day. She is truly sorry for the devastation caused. What has been the evidence so far this morning . Angela van den bogerd was personally in charge of some of the cases. She was also involved in the failed Mediation Scheme in 2019. She has been asked about one case in particular. That was the Sub Postmaster at Martin Griffiths, who took his own life by stepping in front of that these family accuse the post office of hounding them for tens of Tens Of Thousands of pounds. Now, Angela Van Den Bogerd has admitted that faulty communications where the heart of how the can post Office Conducted its dealings. A letter from Martin Griffiths is daughter after his death complained about the disgusting way that there family had been handled after his death. She was asked about the £140,000 that death. She was asked about the £1a0,000 that was offered to Martin Griffiths in exchange for dropping any other legal course. Even though his family had came under the Mediation Scheme at the time. She was also asked about this being an incentive for confidentiality. She did say that that was part of the incentive there. But she went along with it. She was asked whether that was the compassionate way to move on with this. She acknowledged that that wasnt the on the top of her mind. She didnt intend to suppress confidentiality. You have been talking to some of the Postmaster Masters and mistresses who have been affected by this. What has been a reaction to this testimony . The . Reaction to this testimony . They have caught reaction to this testimony . They have caught her reaction to this testimony . Tie have caught her apology a non apology. When said post mistress who became bankrupt and had to sell a home, said that she thought that the whole thing was a non apology and she had to step out twice yesterday as Angela Van Den Bogerd was giving evidence. Partly, because she said she doesnt have a filter and didnt want to interrupt proceedings here. But partly, also because she is dealing with Health Issues and she had to keep her Stress Levels down. Today, when Angela Van Den Bogerd did say that pr and comms were always a consideration in the post offices dealings, there were people shaking their heads in the room at the use of the word disgusting. They have been going this for this for decades. They have been waiting for accountability and financial redress. They want to be here when his questions are being asked. Several of them have said that this is a moment that they had been waiting for. But that doesnt mean its easy. Waiting for. But that doesnt mean its eas. ~ waiting for. But that doesnt mean its eas. , ~ ,. , its easy. Thank you very much for oininu us its easy. Thank you very much for joining us from its easy. Thank you very much for joining us from the its easy. Thank you very much for joining us from the inquiry. Its easy. Thank you very much for joining us from the inquiry. You i its easy. Thank you very much for. Joining us from the inquiry. You can follow it live on the bbc website. And also on the bbc iplayer. Actress ashleyjudd tells the bbc that the overturning of one of Harvey Weinstein� s Rape Convictions is an act of Institutional Betrayal. She was the first woman to go public with the allegations against weinstein. New yorks highest court has ruled he didnt get a fair trial although the 72 year old remains in prison. He may face a fresh trial. Weinstein was separately convicted of rape in los angeles with both cases seen as landmark moments in the � me too movement. When Harvey Weinstein, one of the most powerful men in hollywood, was accused of rape, it led to an outpouring about a culture of Sexual Assault and misogyny experienced by women Around The World what became known as the Metoo Movement. Many women came forward accusing Harvey Weinstein of forcing them into sex. For years, there was a fear of speaking out, they said, because of his ability to make or break careers. But now the Rape Conviction against Harvey Weinstein that came out of the Metoo Movement has been overturned in new york. The court of appeals said prosecutors had called witnesses whose accusations were not part of the charges against him. That meant it said he was unfairly tried for past behaviour. Harvey weinstein was also convicted of rape in a separate case here in la. Last year, he was sentenced to 16 years for raping a woman in a Beverly Hills hotel. He will remain in prison while a decision is made in new york over whether to retry him. Harvey weinstein� s lawyer has commended the appeals court, he said, for upholding the principles that should govern a criminal trial. In this courthouse behind us at that trial, the law was not applied fairly to Harvey Weinstein. You cant throw out 100 years of legal precedent because someone is unpopular. Harvey weinstein� s conviction in california is also being appealed. His legal team are looking into what implications the new york ruling could have here. Emma vardy, bbc news, los angeles. You know, whats important to know is that a courtroom is not a safe environment for survivors of male Sexual Violence. They can be very traumatising spaces. You know, the most dangerous place in america for a woman is in her home. We know the men who assault and rape and murder us. And a lot ofjudges are still catching up to that reality. And juries dont necessarily know that information either. We still think of rape as stranger rape as someone who jumps us in an alley. And so a courtroom isnt necessarily even if harvey were retried and convicted in the state of new york, the place where survivors are going to get their healing. And thats what we need. Thats what we need. It may be a fair outcome if he were convicted in new york, and that would sure be a magic wand. But survivors need trauma informed help and for men to stop raping women. His lawyer said that everyone has the right to justice. He said even people who are very unpopular in our society, no one is above the law, but no one is below the law either, he said. And i agree with that. Yes, of course i do. Everyone deserves justice and i support due process. I had the opportunity to meet The Great Supreme Courtjustice ruth bader ginsburg, and we talked about due process, even for people who are accused of the most egregious sexual crimes. And actually right now at the university of kentucky, where i did my undergraduate degree, a couple of our former student athletes experienced terrible Institutional Betrayal and have accused my university, of which im very proud, in which i love, of complicity and and other betrayals. And were going to go through due process there. And i love my university enough to hold it accountable. So i definitely support due process. And theres no doubt that Harvey Weinstein is a serial sexual predator. It doesnt change the fact that he committed these crimes. 0ver100 Women came forward after i was the named source in the New York Times investigation. And on that point, a separate 16 year sentence handed down in california is not affected. He will stay in prison. He wont be freed. Does that bring you and other survivors any sense of comfort, any Sense Ofjustice or that healing that youre describing . You know, its more complex than that because i dont think the carceral system in the United States does perpetrators of male Sexual Violence any favours either. You know, what i would love to have is a Restorative Justice conversation with Harvey Weinstein. You know, i think that its stories, its narrative that helps change hearts and minds. Im not about punitive measures. Im about community and safety and belonging and forgiveness. I forgave Harvey Weinstein a long time ago and it was no favour to him. I did it for myself. And, you know, its a whole other conversation in terms of the american carceral system. But harvey hasnt had a change of heart. He doesnt necessarily his last words when he was convicted and he was walking out of the courtroom. So how does this happen in the United States . You know, and what would be a more satisfying outcome is if men looked at their entitlement to female bodies and thought, that is a person of dignity, she is a person of worth, and i do not have the right to encroach on her bodily autonomy. That would be satisfying. To china next. We are expecting the us secretary of state, Antony Blinken to give a speech. We will be back live in beijing as soon as he appears at the podium. This is bbc news. We are expecting a News Conference by the us secretary of state, Antony Blinken after his talks with the chinese president. There is the podium waiting for that News Conference. We will go to it as soon as he appears at that podium. Some of the news. First minister, humza yousaf is preparing to give a speech in dundee. The bbc understands he will not be announcing his resignation despite the scottish conservatives tabling a vote of confidence. Thats likely to take place at Holyrood Next week. 0ur scottish Political CorrespondentDavid Henderson has the story. The bute house agreement lasted less than 1,000 days, but it brought green ministers into government for the first time anywhere in the uk and with them came a raft of green policies. So what do voters think now theyre gone . I think its sad because i think the greens are a good influence on the snp, but i guess weve had a Minority Government before, so i guess its going to happen again. Yeah, like, ivote green most of the time. But, yeah, it hasnt been brilliant. For months, this Power Sharing Deal was under pressure, with key plans like the Deposit Return Scheme stalled, then ditched. Chanting trans rights the final straw a row over the pause on the prescription of Puberty Blockers for under 18s, and the scrapping of climate targets. So now the deal� s collapsed, theres pressure on humza yousaf to change direction. But the Balance Of Power at holyrood means its not that simple. With the greens backing that no confidence vote, the alba partys sole msp is crucial. Well, luckily for humza, hes put the Decision Making power of the parliament effectively into the hands of one of the brightest and best and most responsible msps in the parliament, which is ash regan of the alba party. Shes one of the few adults in the room. So he has the opportunity to try and secure her vote, but hell have to work at it. And what now for the greens . Theyre out of office, but not they think out of power. Wherever we are in the parliament, i we will fight for our principles,. And whereverwe are, we canwirx you know, one of our Flagship Policies free Bus Travel For Under 22s was a victory that we won from the Scottish Government before we entered government for the first time. So we can win in government, l we can win out of government. So the scenes set for days of horse trading, then a knife edge vote we are going straight to beijing. We we are going straight to beijing. Want to strengthen our high level channels of communication. I had some constructive conversations with president zine. I made sure that we would be able to work together. Those discussions were made followed by senior level visits. To help lay the foundations for communication with president biden. 0ur leaders agreed on concrete steps to cooperate on issues that matter to our people. I reduce the risk of misunderstanding and miscalculation. In a month since then, we have focused intensively on advancing those issues. We have returned to china this week to take stock of those issues. To see what has to be done so that we can deliver tangible results. That has been the focus of our meetings over the last few days. We had met with the president and his ministers. Since the woodside summit, we have advanced our cooperation on other synthetic drugs. Specifically, prc has taken an enforcement action against some companies. Because of their chemical ingredients that make up some of these products. The us and china have set up a Working Group to collaborate on policy making and Law Enforcement and technical expertise. Thanks to Working Group efforts, we are cooperating on Law Enforcement, to track illicit drugs. We are sharing best practice and closing loopholes that criminal enterprises used to launder money. This is important progress, but more needs to be done. In our discussions, we emphasise the importance of the prc taking action, for prosecuting individuals who are you manufacturing drugs. We must take action on disrupting this trade. We have also resumed direct Military Communications on all levels. Us and prc defence officials met in january. Air unable personnel held talks. We have direct, clear open lines of communication. To avoidance calculations. I am communication. To avoidance calculations. Iam pleased communication. To avoidance calculations. I am pleased to announce that early today we held the first us pcr talks and an artificial intelligence. We said our views on the Safety Concerns and how best to manage them. We also talked about ways in which we can continue to grow the ties between our countries. Particularly, the educational exchanges. We want to create opening conditions for these programmes. I had a chance to meet yesterday with some american and Chinese Students who out lea