Team of full time and serving up this kind of bowling. That ball took down mohammad rizwan. Although pakistan lost all their wickets, they did enough, just, to make a score. To reach 287 would take all of the dutch courage. They made a start with style, the netherlands, but then they make misjudgments. One player got to 67. When he was bowled, pakistan could sense a gentle finish. The dutch all out and more than 80 runs short. But this world cup as their platform and through it all they will keep smiling. Football and paul pogbas failed drugs test has been confirmed with a positive result in his b sample. The former Manchester United and Nowjuventus Midfielder was suspended in august after an initial random drugs test found elevated levels of testosterone in his system. If the 30 year Old World Cup winner is found guilty of doping, he could be banned for between two and four years. Elsewhere, the row over var continues. Liverpool were denied a goal against spurs at the weekend which turned out to be an error. They lost the game. So to try to prevent more incidents, this weekend, the off field field var will confirm the outcome of decisions before notifying the on field referee. The subject has been the talk of all the pre match Press Conferences today. It was a mistake, except it. Its always difficult, humans make mistakes but machines have to avoid it. Thats why the var is to reduce humans making the mistakes that we do. But at the end, the machines have been leaked. It happened, with a mistake and hopefully we finish and getting better, improving. I trust the var and how we manage the var~ i trust the var and how we manage the var~ i i trust the var and how we manage the var. I trust the cabot not the driven the var. I trust the cabot not the driver. Thats the problem. For me its about driver. Thats the problem. For me its about simplifying the situation. After many years, seeing how it situation. After many years, seeing how it works i think the most important how it works i think the most important is to return to give the power important is to return to give the power more to the referees. Max verstappen has taken his 10th Pole Position of the season at the qatar grand prix. He was dominant in qualifying for sundays race, finishing nearly half a second quicker than the mercedes pairing of George Russell and lewis hamilton. First though, theres a sprint race in Doha On Saturday and if verstappen finishes in the top six in that, then hell seal his third successive world f1 title. Thats all the sport for now. Good stuff. Thank you for that. The United States and china could arrange a meeting between the two president s joe biden and xijinping. The white house has invited the chinese leader to the Asia Pacific EconomicCooperation Forum in San Francisco next month. Plans are still uncertain and beijing officials have yet to give their approval. In 2022, joe biden and xi jinping held a meeting at the g20 summit in bali. It was the last time the two president s were seen holding talks together. A little earlier, mr biden was asked about a meeting. This is what he had to say. Asa as a warning it is quite quick. There is no such meeting set up but it is a possibility. They go. I told you it was brief. Live now to danny russel former Assistant Secretary Of State for east asian and pacific affairs, and special Assistant To The President for asia under barack 0bama. Currently Vice President at the Asia Society Policy institute. Thank you for coming on The Programme. Thank you for coming on The Programme thank you for coming on The Programme. Thank you for coming on the rouramme. ~ ,. ,. ,. , programme. Thank you. Glad to oin. First of an, programme. Thank you. Glad to oin. First of all. Do programme. Thank you. Glad to oin. First of all, do you i programme. Thank you. Glad to oin. First of all, do you think i programme. Thank you. Glad to oin. First of all, do you think this i programme. Thank you. Glad to join. First of all, do you think this will first of all, do you think this will go ahead next month . I first of all, do you think this will go ahead next month . First of all, do you think this will go ahead next month . I think it is more likely go ahead next month . I think it is more likely than go ahead next month . I think it is more likely than not. Go ahead next month . I think it is more likely than not. Although. Go ahead next month . I think it isj more likely than not. Although we dont know, the chinese always like to keep their options open. They are tactical when it comes to washington to wrestle with the agenda and the issues. And i see that the chinese system itself doing the things it would expect it would do to prepare whilst that is not a guarantee it is certainly a clue. And whilst president xijinping certainly a clue. And whilst president xi jinping skipped the recent conference in india that he must understand that if he fails to attend the impact meeting which is something that chinese president s always go to, that would ignite a lot of speculation about, maybe he is in trouble at home, the economy is in trouble at home, the economy is so bad in china, all sorts of things that china dont want to be seen as. ,. , � , things that china dont want to be seen as. ,. , � ,. , ~. , seen as. Ok, so lets work on the basis that seen as. Ok, so lets work on the basis that it seen as. Ok, so lets work on the basis that it is seen as. Ok, so lets work on the basis that it is going seen as. Ok, so lets work on the basis that it is going ahead. Seen as. Ok, so lets work on the basis that it is going ahead. We l basis that it is going ahead. We dont know. Why does it matter . Why is a meeting between these two men so significant . So significant . Well, it is significant. So significant . Well, it is significant. A so significant . Well, it is significant. A leader so significant . Well, it is significant. A leader meeting, isnt going to cure all the onus is on the us china relationship. But on the other hand, the only thing that can keep the relationship from getting worse is a leaders meeting. Xi jinping has amassed so much power in the system that if you are not talking to him, you might be wasting your time. Talking to him, you might be wasting yourtime. It talking to him, you might be wasting your time. It is very hard to get decisions made or behaviour changed by going to lower ranked officials. The chinese system takes its cue from the leader. So if xijinping decides to travel to the us, Sit Down With Biden and talk through the issues that is a signal for the entire chinese system that it is ok to engage with american counterparts, it is kind of permission. And the. 0k. Interesting. Permission. And the. 0k. Interesting. This permission. And the. 0k. Interesting. This relationship specifically between the two personalities, the two men, what is it like and does it matter . It like and does it matter . Well, the have it like and does it matter . Well, they have a it like and does it matter . Well, they have a unique it like and does it matter . Well, they have a unique and they have a unique and strong personal relationship because they have very in depth and candid discussions when they were both Vice President s 11 or 12 years ago. And i think the personal relationship between the two men is one of the very few positive factors remaining in the us china relationship. But the pandemic prevented any kind of in person engagement. There was not a good substitute in diplomacy and there is tremendous friction between there is tremendous friction between the two countries so there is a lot of strain on the relationship. Nevertheless, it is a net positive if they can engage in person. Always aood to if they can engage in person. Always good to great if they can engage in person. Always good to great your if they can engage in person. Always good to great your thoughts. If they can engage in person. Always good to great your thoughts. We if they can engage in person. Alwaysj good to great your thoughts. We will have you back in one months time of this meeting does go ahead and see what we can learn from that. For now, thank you for coming on The Programme. Over the past few months, a new Weight Loss Trend has been getting a lot of attention especially in the us. Weight loss injections had until recently only been prescribed to people with diabetes. But the us food and Drug Administration approved them as a treatment for chronic obesity. However, new research has found that these appetite supressing injections can cause severe side effects, including Stomach Paralysis and pancreatitis and doctors have called for warnings to be placed on the drugs. The Drugs Manufacturer novo nordisk has responded to the findings, saying it stands behind the safety and efficacy of all of our glp 1ra medicines when used consistent with the Product Labeling and approved indications. The injections are apparently taking hollywood by storm and even elon musk has admitted they are the secret to his physique. Joining me now is dr simon cork, who is a Senior Lecturer in physiology at Anglia Ruksin University and mohit sodhi, one of the authors of the study. Thank you both are coming on The Programme. Thank you both are coming on The Programme thank you both are coming on The Programme. Lets i thank you both are coming on The Programme. Lets start programme. Good evening. Lets start with ou, programme. Good evening. Lets start with you. What programme. Good evening. Lets start with you, what are programme. Good evening. Lets start with you, what are The Programme. Good evening. Lets start with you, what are the headlines with you, what are the headlines from this study . Irate with you, what are the headlines from this study . With you, what are the headlines from this study . We conducted a study where from this study . We conducted a study where we from this study . We conducted a study where we investigated from this study . We conducted a study where we investigated the | from this study . We conducted a study where we investigated the risk of a number of gastrointestinal adverse events with patients who used the injection, as you mentioned and compared those to people who use another drug and that is chemically distinct from this injection and they are specifically marketed for weight loss. We compare the to will me found that there was an increase risk of gastroparesis, that is the quote and quote Stomach Paralysis, pancreatitis as well as bowel obstruction. Pancreatitis as well as bowel obstruction. Obstruction. Ok, so increase risk and to what obstruction. Ok, so increase risk and to what extent . Obstruction. Ok, so increase risk and to what extent . So, obstruction. Ok, so increase risk and to what extent . So, the obstruction. Ok, so increase risk. And to what extent . So, the events themselves and to what extent . So, the events themselves actually and to what extent . So, the events themselves actually quite and to what extent . So, the events themselves actually quite rare. And to what extent . So, the events themselves actually quite rare. If. Themselves actually quite rare. If you look at our paper, we mentioned that about 1 of the patients using their had gastroparesis. That number doesnt seem like a lot however, when you think about the fact that there are millions and millions of people taking these medications for weight loss, that number can translate up to Tens Of Thousands or hundreds of thousands of people who could potentially be affected by these adverse events. Ic. Could potentially be affected by these adverse events. These adverse events. Ic. Lets cross out these adverse events. Ic. Lets cross out assignment. These adverse events. Ic. Lets cross out assignment. What i these adverse events. Ic. Letsl cross out assignment. What you these adverse events. Ic. Lets cross out assignment. What you make of that . I cross out assignment. What you make of that . ~ � , cross out assignment. What you make of that . , � ,. ,. ,. , of that . I think its an important stud. Of that . I think its an important study what of that . I think its an important study. What it of that . I think its an important study. What it highlight of that . I think its an important study. What it highlight is of that . I think its an important study. What it highlight is the i of that . I think its an important i study. What it highlight is the need for these study. What it highlight is the need for these drugs to be prescribed under for these drugs to be prescribed under medical supervision. I mean, it doesrrt under medical supervision. I mean, it doesnt take much searching on the internet to be held to find an ontihe the internet to be held to find an Online Pharmacy that will sell you these Online Pharmacy that will sell you these drugs without very much scrutiny these drugs without very much scrutiny. In fact, i was able to be offered scrutiny. In fact, i was able to be offered these drugsjust scrutiny. In fact, i was able to be offered these drugs just today for a monthiy offered these drugs just today for a monthly sum. I think these drugs are not monthly sum. I think these drugs are hot without monthly sum. I think these drugs are not without risk, they are very effective not without risk, they are very effective and for the vast majority of people effective and for the vast majority of people they are really, really say. Of people they are really, really say and of people they are really, really say. And we have to look at the context say. And we have to look at the context in say. And we have to look at the context in which we are working here which context in which we are working here which is context in which we are working here which is that context in which we are working here which is that obesity is a huge risk factor which is that obesity is a huge risk factor itself for chronic disease, it increases your risk of stroke, cancer, it increases your risk of stroke, cancer, Cardiovascular Disease and diabetes cancer, Cardiovascular Disease and diabetes. The vast majority of people diabetes. The vast majority of people taking this drug, the benefit of losing people taking this drug, the benefit of Losing Weight are greater than the risks of Losing Weight are greater than the risks associated with taking them the risks associated with taking them but the risks associated with taking them but we do need to make sure that the them but we do need to make sure that the people who take these drugs are being that the people who take these drugs are being given the right kind of medical are being given the right kind of medical monitoring and notjust being medical monitoring and notjust being prescribed them and letting them being prescribed them and letting them just go off and taking them without them just go off and taking them without supervision. Ic. Them just go off and taking them without supervision. Without supervision. Ic. Is that a rinci le without supervision. Ic. Is that a principle that without supervision. Ic. Is that a principle that you without supervision. Ic. Is that a principle that you would without supervision. Ic. Is that a principle that you would agree i without supervision. Ic. Is that a i principle that you would agree with as well. The fact that there are risks to obesity themselves and that there are benefits to taking this . We do agree. Aside from the fact that its very effective at treating patients with diabetes, in the context of weight loss, we do agree that patients who are morbidly obese, they are at higher risk of some of the indications that the other fellow mentioned. Some of the indications that the otherfellow mentioned. However, patients who are maybe trying to lose that last ten to £15, celebrities who may be otherwise healthy who started to use these medications and they may not be clinically obese. So i think it is very important to make sure that patients are aware of these potential adverse risks, although rare they may happen. Its very important that, you know, patients are monitored closely by their physician and they are made aware of these particular adverse effects so they can make that decision whether or not they choose to continue using these or initiating therapy with these or initiating therapy with these medications to help them reach their goals. I these medications to help them reach their coals. ,. ,. , their goals. I see. The people who are watching their goals. I see. The people who are watching this their goals. I see. The people who are watching this and their goals. I see. The people who are watching this and havent their goals. I see. The people who| are watching this and havent been aware of this before it maybe do have a problem with their weight and on now interested in this, what would your message be . I on now interested in this, what would your message be . I think that those people would your message be . I think that those people who would your message be . I think that those people who are would your message be . I think that those people who are in would your message be . I think that those people who are in the would your message be . I think that those people who are in the high those people who are in the high levels those people who are in the high levels of those people who are in the high levels of weight, people who are really levels of weight, people who are really obese, they are the people that these dru