bucha, borodyanka, mariupol. so i don't have, you know, it's not about me, it's more about russia. the first asylum seekers could be flown from the uk to rwanda in weeks, according to the british government. the scheme aims to deter people crossing the english channel, but critics say it is inhumane. more than 340 people are now known to have died in the south african province of kwazulu—natal, in the worst flooding there in decades. it's hoped new research mapping the genetic code of brain tumours could lead to more accurate diagnoses and potentially better treatments. joe root has stepped down as england test captain after his side's defeat by the west indies. appointed in 2017, he holds the record for the highest number of matches and wins as captain. the russian defence ministry says it has warned it'll intensify attacks around the ukraine capital, kyiv, after accusing ukraine of targeting russian border towns. moscow also claims its sea—based cruise missiles have struck a factory outside kyiv which produces anti—ship missiles, including the type which — according to ukraine — hit russia's flagship, the moskva. russia confirmed the 12,000—ton cruiser from its black sea fleet had sunk but says it went down in rough seas as it was being towed to port, after a fire caused its ammunition to explode. tim allman reports. the scourge of the black sea now buried at the bottom of it. but how the moskva got there is still disputed. ukraine says it hit the ship with cruise missiles launched from the coast. russia would only admit there had been an explosion onboard and it then sank in bad weather. if the ukrainians were responsible, it would be the biggest warship to be sunk by enemy action since the second world war. this is a tremendous victory for ukraine, even if they didn't directly contribute to the sinking. and it's an enormous defeat for russia because it indicates that the russian armed forces simply aren't up to snuff in terms of modern military capabilities. perhaps not, but it does beg the question how will russia react? these were air raid sirens heard overnight in the western city of lviv for the first time in several days. and there were reports of powerful explosions in the capital, kyiv. in his latest video message, president zelensky made reference to the fate of the moskva. he praised the ukrainian people, those who stopped the advance of endless columns of russian equipment, those who proved that russian planes were defenceless, and those who proved that russian ships can only go to the bottom of the sea. but in the east of the country, invading troops continue their operations. the ukrainian government fears their main goal now is to destroy the donbas region. russia may have sustained a heavy defeat, but it is still very much in this war. tim allman, bbc news. ukraine's president volodymyr zelensky says european countries that continue to buy oil from russia are aiding the country's war against them — and they will have blood on their hands. he's urged western leaders to speed up the delivery of military aid to help ukraine. our correspondent clive myrie is in kyiv and he spoke to president voldymyr zelensky about the conflict. first, he gave us his reflection on spending time with the president. very affable, very charming, he knows how to work the media, let's be clear about that. ifound him also to be at the same time genuine. he has been an office barely three years, and he has having to deal with a conflagration that has completely swallowed up his country. has killed many of his citizens. and he is having to deal with all that and they say that "cometh the hour, cometh the man" and there has been speculation that a former comedian and actor turns out to be their head of state, he has risen to the challenge and that has been recognised by his people here and millions of around the world. he was utterly charming and deeply concerned about the situation his country is in. i could not begin to imagine the pressure that he is under. he looked tired when i first saw him, emotionally drained, and that is after 50 days of war. we have no idea how longer this will go on for. i could absolutely see why he has garnered the respect of so many people around the world in his handling of this crisis. i could see him physically tense up when he started talking about war crimes and talking about what russian troops are alleged to have done. he has visited the north—western suburbs behind me here, borodyanka, bucha, he has seen the body bags. i saw his face crumple, i saw him tense up, and it is deeply painfulfor him. i sayed directly, are you going to be able to sit across a negotiating table and talk to the head of state or the representative of a nation that is alleged to have committed those kinds of atrocities to your people? he told me it would be very, very difficult but he was willing to try, to try to end this crisis. you get a flavour of that in my interview coming up now. mr president, clive myrie, a pleasure to meet you. it's good to see you. for the entirety of the war volodymyr zelensky has called this heavily fortified building home in the centre of kyiv. how difficult has it been for you to be here through all this without your family? it's myjob. i have to do it and it's difficult without a family being anywhere. his wife and children are safe at an undisclosed location. his companions here, heavily armed troops, sandbags and mines. at the start of the war they walked around in the darkness here, afraid of russian shelling. it's like our country, like our country is going through the dark. going through the darkness. to the victory, i hope so. as we enter what is labelled the situation room, the president gets a text. from macron. emmanuel macron. he phoned me, we have connections. 0k, he dropped you a message, i can say. i do know! he just tried to reach you, my friend. when you have some time, so we are holding up mr macron. yeah. i can see the plus 33, that's paris. yeah. 0k? a few minutes later he returns. his preoccupation, a renewed military onslaught about to begin in the east. are you getting the right weapons you need from the west? translation: we need weapons today so we can fight. _ we cannot wait until some country decides to give or sell us weapons. some have not decided on this and we cannot wait two or three weeks or a month. the united states, united kingdom and some european countries are helping but we need it sooner, we need it now. is it enough? we don't think so. the priority word is sooner, the priority word is quickly and the priority word, now. he is a president who has been cut off from his people, a citizenry suffering unimaginable horrors at the hands of a ruthless adversary. he is full of hate, he says, for russia's troops and their leaders, gradually limiting the scope for peace talks. how do you sit across the table to try to stop the war? how do you do that? bucha is in this process closing this possibility. bucha, borodyanka, mariupol, so i don't have, you know, it's not about me, it's more about russia. they will not have so many chances. in the long period to speak with us. and what of those european countries? despite other sanctions still sending billions to russia in oil and gas revenues. translation: we don't understand how you can make money out of blood. - unfortunately some european countries have done this. before the war began i spoke to chancellor merkel and said, if a full—scale invasion of ukraine happens they will go further into poland and, after that, they will be on your borders of germany. if that happened, would you say to your people it's fine, it's business, it's just business? how do you maintain hope in the future, given everything that's happened? translation: it's not hope, its certainty. - that you will win. yes, of course. mr president, thank you. thank you so much. as we've been hearing attacks continue around ukraine's capital kyiv. our reporter anna foster is in kozarovychi, just north of the city — and we can speak to her live now. iamon i am on the outside of the city and this is the remains of a missile lying in somebody�*s back yard in a street which connects these houses which have been so badly damaged by the fighting here. i can see them fixing the power lines and doing what they can to try to bring areas like this back to life but at the same time we heard reports this morning of these three missile strikes in the south of kyiv. russia says it had successfully a factory that was producing anti aircraft and anti ship missiles. this factor is trying to produce and bring some spark of life back but there are still the threat from russia the capital is not entirely out of the thoughts. who is doing that rebuilding work? are some of them men not being conscripted to go to towns and cities to try to help the infrastructure to keep going? it seems like that is very much the case at the moment. when you walk around place like this at the moment it is mainly men doing the work because as you say they were told they were not to leave the country and to stay behind and fight. so these volunteers are gripping together. i can seejust these volunteers are gripping together. i can see just over the fence the other is that checkpoint here and there are still lots of checkpoints in the area that are being manned by the volunteers who have stayed behind and they are still checking peoples id and making sure everybody who is in this area are supposed to be here. and it is people rebuilding their own houses but still such a slow process. how do you get rid of something like this? you have to wait for somebody to take it away for you and clean away the debris. for a lot of people in these areas around kyiv, these many towns that fell under russian control, they have a lot of work to do to reconstruct what is here before they can in many cases as you rightly point out bring back their families, their partners, their children, and actually try to rebuild their lives after the rebuild their lives after the rebuild their lives after the rebuild their homes. i don't know if you have been able to get any verification where you are but there are reports we have had from the agencies of ukraine missile manufacturing site ot side of kyiv hit by a russian missile, do you have any verification of that? —— much outside of kyiv. i have noticed that the ukrainians are always extremely cautious about confirming attacks, the location of attacks, so things like this are often really hard to verify and it is only if you can actually get anywhere near the location and see for yourself and again the unprotected, that you can actually try and work out the truth of what has happened here but certainly had the stories of the south of the city this morning being hit, this particularfactory, again, from russia, ukraine have been very quiet but it was certainly hit with the russia narrative they said they would concentrate their fire on facilities around kyiv if as they say ukraine does not pull back its efforts at the russian border. benjamin duere is an international legal analyst and join us form the hague. there has been a lot of focus on war crimes and any eventual prosecution. what are your assessment of that? the developments in the conflicts are obviously quite concerning from are obviously quite concerning from a legal perspective. what we have seen as an undermining of fundamental norms of international law and certain acts within a conflict may amount to war crimes so maybe even crimes against humanity which can also be prosecuted at international level. and so these developments are certainly quite concerning. developments are certainly quite concerning-— concerning. when you say international _ concerning. when you say international norms - concerning. when you say international norms and l concerning. when you say i international norms and war, concerning. when you say - international norms and war, does any side stick to those when we see conflicts went round the world? we do conflicts went round the world? - do certainly see a number of potential violations of these norms but we also see adherence to them so the fact that they are violets does not mean they are useless, i think. bucha and mariupol, tell us if you think that is enough evidence for them to be presented in court. there are three levels, _ them to be presented in court. there are three levels, the _ them to be presented in court. there are three levels, the ukrainian - are three levels, the ukrainian domestic parties have launched investigations and there are attempts by international organisations like the united nations but there are also investigations by the international criminal court and they are based on this assessment, on the reports that we have seen, that there are potentially serious violations of international law by both sides of the conflict and we will see in the coming weeks and months, certainly, a furtherance of these investigations and potentially also at a certain stage arrest warrants are even indictments of individuals. we have seen both russian and ukrainian leaders using the word genocide a lot. that has a very specific definition, doesn't it? it does from a legal perspective, a very narrow definition of what constitutes genocide and therefore in the past we have seen only very few cases where it has been confirmed by the international court that in fact indeed genocide has been committed and so therefore it is very hard to establish whether indeed genocide is going on, so personally, i would indeed genocide is going on, so personally, iwould be indeed genocide is going on, so personally, i would be reluctant or hesitant to speak of genocide at this stage without clear international investigation. this mi . ht international investigation. this miaht be international investigation. this might be outside your area given that you obviously focused on the legalities, but is there political reasoning in terms of talking about war crimes at the moment because it does have an impact on decisions? ultimately, the aim of everyone is to stop innocent people being killed and injured rather than necessarily focusing on what happens afterwards? exactly. certainly, international law is often very much linked to political developments and can play our role, i think, political developments and can play our role, ithink, in political developments and can play our role, i think, in deterring future violations and future suffering so i do think that international law can play a role in shaping political decisions.- shaping political decisions. thank ou so shaping political decisions. thank you so much _ shaping political decisions. thank you so much for— shaping political decisions. thank you so much forjoining _ shaping political decisions. thank you so much forjoining us - shaping political decisions. thank you so much forjoining us from l shaping political decisions. thank you so much forjoining us from the hague. plans to send some asylum seekers who arrive in the uk to live in rwanda have been described as "absolutely chilling" by charities and politicians. britain's of those arriving in the uk illegally would be considered for relocation to rwanda. the government says the system would reduce people—smuggling and discourage people from trying to reach britain in small boats. but the united nations' refugee agency said people fleeing conflict and persecution deserved compassion and empathy — and should not be traded like commodities. joining me now is our political correspondent — jonathan blake. there has been some scepticism of the timing of the government and borisjohnson under huge pressure for partying during covid restrictions so his position is precarious politically and some discussion at that this might be trying to shore up his brexit thought bank. this is an attempt from the government to demonstrate they can do something to limit on and it's stop smal bought crossings come across the english channel and people attempting to get into the uk and claim asylum having taken that very dangerous route. it is something borisjohnson has made a political priority of his own to demonstrate tighter control over immigration after brexit and this is frankly an embarrassment for him and his government on a daily basis to see in some cases hundreds of people making thatjourney see in some cases hundreds of people making that journey with see in some cases hundreds of people making thatjourney with very little the government has been able to do about it. we have this new policy, up about it. we have this new policy, up promise to transfer people to reminder on arrival in the uk where they will then be able to claim asylum and left. —— rwanda. we have asylum and left. —— rwanda. we have a few more details about the timing and logistics and are told the m of the garment is to have it up and running if weeks if not a small number of months and in terms of casting is a bit less clear, ministers not putting a figure on how much this will potentially cost in the long run. that is one of the criticisms of them that it will be a particularly costly policy but nevertheless the home office minister tom pursglove seeing this morning that something had to be done. —— has said this morning. we have to get this under control. it is completely unacceptable and unsustainable to have thousands of people making these dangerous crossing, the channel, for example, as we move forward. and that is why doing this in this way will help us to stop that. it is one intervention amongst many but it should mean that not only are people not risking their lives, but we are also getting under control some of these costs. for example, we are spending nearly £5 million a day at the moment accommodating people and hotels. i think your viewers at home would say that's unsustainable and not acceptable. the question of how much this will cast as part of the argument as to whether it will ever actually even happen because it is so difficult logistically to sort out and there is some opposition within the governing conservative party. there was a chorus of criticism from opposition parties when the plans were announced yesterday but there is some unease on the conservative backbenches where most conservative mps have welcomed this policy and are behind it and believe it will go down well with a lot of voters in their constituencies, there are some conservative mps speaking out. the most vocal of those so far the former international velma secretary, conservative mp andrew mitchell. —— international secretary. the problem with this scheme they have announced is that i do not think it will work, it is not practical, it is being condemned by the church and civil society, it is immoral and above all for conservative advocates it is incredibly expensive. the costs are eye watering, you are going to send people 6000 miles into central africa... questions about the political future of borisjohnson will be raised in the near future. of borisjohnson will be raised in the nearfuture. there are of borisjohnson will be raised in the near future. there are local elections coming up in the uk next month which will be a test for him as well as the other uk parties. he has faced accusations he misled mps regarding what you said about parties in downing street and other whitehall buildings during the pandemic. he has received a fixed penalty notice which he has paid. could that be mortar, for him and other government figures? the police investigation continues and after that there will be the report by the civil servant who was looking into it, sue gray. tensions are high in occupied eastjerusalem as christians, jews and muslims prepare to celebrate easter, passover and ramadan at the same time. there have been clashes between israeli forces and palestinian demonstrators at al aqsa mosque. tear gas has been fired and reports suggest at least 150 palestinians and three israeli policemen were injured. 395 people are now known to have died in the south african province of kwazulu—natal in the worst flooding in decades. days of torrential rain washed away homes, roads and bridges, prompting the government to declare a state of disaster on wednesday. electricity and water have been restored to some areas, but relief teams are stretched to capacity. joining me now is thando lukuko, who is the south africa coordinator for climate action network.t can you tell us what you're hearing and seeing about the floods? what can you tell us what you're hearing and seeing about the floods? what we are hearin: and seeing about the floods? what we are hearing as — and seeing about the floods? what we are hearing as there _ and seeing about the floods? what we are hearing as there is _ and seeing about the floods? what we are hearing as there is very _ are hearing as there is very widespread devastation, particularly damage along the coastline as one can imagine with the water being so close. in the city there is varying levels of development. that the geography that is quite hilly so there are parts that have been literally swamped we have also been completely flooded and most vehicles are not able to travel. homes have been fairly demolished. there are images of peoples backyards that have been split into, peoples homes have been split into, peoples homes have been split into, peoples homes have been split into —— split into two parts and it is worse because landscape is quite flat and because i have been floods more recently in south africa and there the ground is quite hard so when the rainfall came it was almost like the rainfall fell on tar roads but this is on gravel roads. mudslides and damages of local bridges and local infrastructure has been quite extensive. as you mention, the death toll which continues to rise so it is a great cause for concern for us and if anything it positions itself as a great beacon of why we need urgent climate action in south africa and obviously southern africa and other parts of the continent as well. in and other parts of the continent as well. , ., , ., well. in terms of getting help to eo - le, well. in terms of getting help to people, obviously _ well. in terms of getting help to people, obviously very - well. in terms of getting help to people, obviously very difficult. | well. in terms of getting help to l people, obviously very difficult. is enough being done? that people, obviously very difficult. is enough being done?— enough being done? that is a difficult one. _ enough being done? that is a difficult one. there _ enough being done? that is a difficult one. there is - enough being done? that is a difficult one. there is work i enough being done? that is a i difficult one. there is work being done. we know that government assets have been deployed to help communities as the can and must again —— and that is a naga station called give to the governors which is trying to help as much as they can and last night the president was there to look at the extent of the damage and one of the tricky things is that covid wrecked havoc on the provincial municipal budget and last year there were tensions in kwazulu which hadda devastating affect on the economy there are so they are not necessarily in a great position to provide great resources. there is mobilising of resources from places outside that province to help but there is was more that could be done and i don't think one could ever have enough support and resources in such a circumstance. irate have enough support and resources in such a circumstance.— such a circumstance. we are seeing extremes of — such a circumstance. we are seeing extremes of weather _ such a circumstance. we are seeing extremes of weather across - such a circumstance. we are seeing extremes of weather across the - such a circumstance. we are seeing l extremes of weather across the globe at the moment. how prepared are south africa for more of this extreme weather? does it need external help? the extreme weather? does it need external help?— extreme weather? does it need external help? the short answer is es. we external help? the short answer is yes- we do — external help? the short answer is yes. we do have _ external help? the short answer is yes. we do have preparations - external help? the short answer is yes. we do have preparations in i yes. we do have preparations in place, we have disaster risk management plans in place and climate change response and adaptation plans which are present in kwazulu and it was a beacon for adaptation around the world. there are some resources to help allocated by the government in similar circumstances but again i will say that definitely much more needs to be done. if you look at the amount of climate finance available to help similar circumstances happening in future, there has not been much that flaw particularly for adaptation into south africa and southern africa more broadly so i think the international community has a bit more of a role to play in providing a direct more resources to sub—saharan africa but also is specifically to south africa to put in place the necessary early warning systems and projects which will help communities become more resilient, communities become more resilient, communities whether rural or urban city centre communities. such damage is quite widespread and usually it is quite widespread and usually it is infrastructure that takes the biggest knock outside the loss of life still to be able to rebuild all of that i think insurance companies often times are caught unawares of this year it damaged such natural disasters can have it so we need to find a way to be able to channel more resources and that resourcing is needed both to save those lives of those who are no displays but also to rebuild the economy and rebuild the infrastructure that has been damaged. rebuild the infrastructure that has been damaged-— rebuild the infrastructure that has been damaued. ., ~ ,, , . been damaged. thank you very much for our been damaged. thank you very much foryourtime- _ brain tumours are the most common cancer killer in people under a0. but treatments have barely changed in years and research into the condition has been very limited. the issue was highlighted recently by the death of the singer tom parker at the age of 33. now, brain tumour patients at addenbrooke s hospital in cambridge are having their cancer genomes — the entire dna — sequenced. the aim is that tumour mapping will lead to more accurate diagnosis. a warning — this report from our medical editor fergus walsh contains images of brain surgery. i've got a rough idea of what's going to happen. i'm going to be partially awake, but i'm going to be woken up during the surgery. daniel is just 34. he's on his way to theatre for brain surgery. i think that's the most scared about is being awake and having someone rooting around in my head. daniel has a large brain tumour, the round white area at the top of this scan. to begin with, daniel is fully anesthetized while surgeons remove part of his skull. but once his brain is exposed, he's woken up and must be kept awake. daniel, how are you feeling? actually, we just need to be a bit careful at the back because that's close to where the part of your brain that moves the right hand side of your body. before removing each piece of tumour surgeons need to be sure it won't affect daniel's speech or his ability to move his body. i want you to just say what you see. so at each step, the team checks his responses. part of daniel's tumour will be sent for whole genome sequencing. its entire dna will be mapped. what that means is essentially we're looking at the abnormalities in the genes that we think caused the tumor in the first place. so we're really able to drill down into the molecular problems in the tumor. daniel's diagnosis, his future rests on what they find in these tubes. dna sequencing used to take months. now it can be done in days. at these labs near cambridge of us biotech illumina. not only does it speed up diagnosis, but reveals what is driving the growth of a patient�*s cancer. nothing can prepare a patient. or a family for the nuclear bomb that detonates at the center of your world i when you receive a diagnosis. jess lost her mother, tessa jowell, to brain cancer in 2018. the former labour cabinet minister spent her last months campaigning for more funding and research into the condition. the brain cancer is the biggest- cancer killer of children and people under 40 in the uk, yet treatment. options have not changed in decades. because this is low grade... just two weeks after surgery, daniel returns to addenbrooke's with his brother to receive his results. this is a diagnosis that is treatable, but it's not a curable condition. ok, so this is something that will be life limiting. about 50% of people survive for 15 years or more. but i think it's important that you understand this isn't something that's going to go away. yeah. wow. i don't know what to say. sure. we have to say anything toward the next 15 years in my life. he's going to kneel to them. a few weeks later ijoined daniel to watch his local football team. he used to play in goal. now he gives advice from the touchline. life is very short, so i want to make the most of it. i just want to get the treatment i can to prolong my life. like six weeks of radiotherapy, five days a week. more than 200 brain tumour patients are taking part in the research, with the hope it may eventually yield new personalized treatments which improve outcomes. fergus walsh, bbc news, cambridge. joining me now isjess mills. she's a founding member of the tessa jowell brain cancer mission ? named after her late mother, dame tessa jowell, who died from brain cancer in 2018. her organisation has provided funding for the study at in cambridge s addenbrooke s hospital. lovely addenbrooke s hospital. to see you, your mother\ wonderful, lovely to see you, your mother was wonderful, a great friend to many of us around the political scene and she was truly inspirational, it is amazing to see you carry on the work she has started. telus about the importance of this research, why are you wanting to fund this work. thank ou for you wanting to fund this work. thank you for having _ you wanting to fund this work. thank you for having me. _ you wanting to fund this work. thank you for having me. this _ you wanting to fund this work. t�*usg�*ua; you for having me. this programme is not being funded by the tessa jowell foundation, it is a wonderful story of how international collaboration can be a source for such brilliant progress in areas of tough challenge like this. the programme is being funded by one of the tessa jowell brain cancer missions who are a pioneering foundation from australia and as part of a national strategy to truly innovate nhs treatment and care so that as per my mother's parting wish every brain cancer agent can receive world—class treatment and the local hospital. —— brain cancer patient. the treatment and the local hospital. -- brain cancer patient.— brain cancer patient. the point is to t brain cancer patient. the point is tot to brain cancer patient. the point is to try to understand _ brain cancer patient. the point is to try to understand more - brain cancer patient. the point is to try to understand more about| brain cancer patient. the point is i to try to understand more about the mutations that drive a tumour and to help with treatment. it is mutations that drive a tumour and to help with treatment.— help with treatment. it is helpful for me to describe _ help with treatment. it is helpful for me to describe what - help with treatment. it is helpful for me to describe what the - help with treatment. it is helpful. for me to describe what the current process is and what happened with mum which speaks to the experience of every patient so when you are diagnosed you are told you have three options, surgery, radiotherapy or chemotherapy and that is at, you are also told that those three options may extend your life by 1a months if you are lucky. my mum was intolerant to chemotherapy so could not see through the course of that. she died 11 months after she was diagnosed. if this programme had been live event she was diagnosed instead of that being the only options to access through the nhs she would have had her tumour comprehensively sequenced, the doctors would understand and much more detail what was driving her cancer and started thinking about some other options that could have had a benefit for her and it is important to say we do not have one single agent that will make brain tumours go from an qw to curable but what we can do is start to offer patients other options which may be repurposed drugs from other cancers which when you are given the news of my family was given gives you this very important thing called hope which is the thing that can enable you to make the unbearable available. forthe you to make the unbearable available. for the time that you have. ., , ., , ., have. your mum when she was l told us about what — have. your mum when she was l told us about what had _ have. your mum when she was l told us about what had happened - have. your mum when she was l told us about what had happened and - have. your mum when she was l toldj us about what had happened and how she realised she wasn't well, well this research and anyway understand what causes brain tumours? ituuihat this research and anyway understand what causes brain tumours?- what causes brain tumours? what is owerful what causes brain tumours? what is powerful and _ what causes brain tumours? what is powerful and important _ what causes brain tumours? what is powerful and important about - powerful and important about precision medicine as it fully integrates basic science or the be “p integrates basic science or the be up to patient bedside care so it serves the full spectrum of the process so it provides very rich environment for scientists to learn about what is causing the cancer, driving at but to the bedside care of the patient that enables doctors to give more targeted treatment and consideration for patients so it really manages the whole spectrum which is what is so powerful about it and it is the thing and time and notjust brain cancer but cancer more broadly, precision medicine is the space in which they will go from being incurable to entire treatable. —— in time treatable. being incurable to entire treatable. -- in time treatable.— -- in time treatable. what are the other options _ -- in time treatable. what are the other options that _ -- in time treatable. what are the other options that might - -- in time treatable. what are the other options that might have - -- in time treatable. what are the | other options that might have been available to your mum other than chemotherapy or to other patients. when she was diagnosed as a result of the extensive work she did and public health when the news became known to friends and colleagues of her diagnosis and prognosis we were an undated offers of advice and informally support from people and all over the world. this formed the genesis of mum's campaign, as we were basically told we had no more treatment options available on the nhs to be being an undated and an informal capacity by advice from people saying you can do x y and z due can get this treatment and thus may well give you more time, lower toxicity, we were really introduced toxicity, we were really introduced to some of the most cutting—edge stuff that was happening and is everything that mum did in her life she fought for 50 years offer career framed around how she could tackle huge issues of inequality and what she saw through that experience and her once was absolutely despicable that if you are a family who happens to have the privilege of these other options you may well have a chance at living a better or longer as a result of it so it is the heart of this campaign to close the inequality gap so as mum would say every single patient in the uk can receive world—class treatment and their local hospital and that is what this programme is the beginning of. me what this programme is the beginning of. ~ ., what this programme is the beginning of. . . . , what this programme is the beginning of. ~ . ., , ., , ., of. we hear many families are lookin: of. we hear many families are looking internationally - of. we hear many families are looking internationally for - looking internationally for solutions but often very expensive to access privately and some countries have great records and others have not. telus what the last few years have been like for your family, as you had to accept the loss of your mother but still focused on this campaign. it is a loss of dimensions _ focused on this campaign. it is a loss of dimensions at _ focused on this campaign. it is a loss of dimensions at is - focused on this campaign. it is a i loss of dimensions at is impossible to fully articulate but for me doing this work everyday as my way and our way of keeping that incredibly unique and extraordinary value and humanity she had alive as a force for good in the world and with the launch of this programme i think she would be very proud of what we are doing. would be very proud of what we are doinu. ., , ., ,, .,~ ., would be very proud of what we are doinu. ., , ., ,, ., ., doing. lovely to speak to you and i think for everyone _ doing. lovely to speak to you and i think for everyone who _ doing. lovely to speak to you and i think for everyone who knew - doing. lovely to speak to you and i think for everyone who knew tessa jowell she lit up the room even when she was really unwell, she was a unique spirit and i think of her so many times and we were lucky to have fun so thank you forjoining us. thank you. fun so thank you for “oining us. thank you-* thank you. good luck with the campaign _ thank you. good luck with the campaign and _ thank you. good luck with the campaign and there _ thank you. good luck with the campaign and there are - thank you. good luck with the campaign and there are lots i thank you. good luck with the | campaign and there are lots of fundraising efforts going on on the cancerfront if you fundraising efforts going on on the cancer front if you do want to donate, more information on the website. some sport news now — joe root has stepped down as england cricket captain. let's speak to louisa pilbeam. not totally unexpected but angle has has its fair share of worries. yes. has its fair share of worries. yes, not unexpected _ has its fair share of worries. yes, not unexpected but _ has its fair share of worries. yes, not unexpected but it _ has its fair share of worries. yes, not unexpected but it is - has its fair share of worries. 1a: not unexpected but it is worth starting with the fact thatjoe root is england's most successful cricket captain, 27 victories to his captaincy, also one of england's best players. already the second highest test runs of all time and scored 1a centuries as captain but if we take the last few months england had the dismal defeat by australia and the ashes at the start of the year where they lost the series 4—0 and the ten wicket humiliation in the third test to west indies most recently in granada takes england to nine matches without a win and this is where it all starts to go wrong forjoe root. he was criticised for making bad decisions as captain and for talking and cliches are saying there was a lot to learn from their defeat but not much change and action so critics began to call for him to go and joe root said in a statement i have loved leading my country but recently it has had home how much of a toll it has taken on me and the impact it has had on me away from the game. he is not living cricket entirely, he is a crucial player and it may help his performances and few can focus on just that. all the talk will turn to who will take over from joe root, ben stokes as vice captain, jos buttler and even stuart broad and james anderton who are coming to the ends of their career have been names put around but they were recently dropped from the england cricket team so not sure what will happen there. ben stokes has been mentioned _ what will happen there. ben stokes has been mentioned is _ what will happen there. ben stokes has been mentioned is certainly - what will happen there. ben stokes has been mentioned is certainly a l has been mentioned is certainly a big favourite but you and your skills as a cricket player and different in terms of what you need to be a captain and they do not always marry up. to be a captain and they do not always marry up-_ always marry up. no, and as i mentioned — always marry up. no, and as i mentioned joe _ always marry up. no, and as i mentioned joe root _ always marry up. no, and as i mentioned joe root as - always marry up. no, and as i mentioned joe root as a - always marry up. no, and as i l mentioned joe root as a player always marry up. no, and as i - mentioned joe root as a player has been one of england's best, they have really relied on him to get through, suffered heavy defeats but he really shone as a leader in terms of his playing skills but the captaincy is different and it comes with a lot of pressure and is mentioned and has statement, he relates and mentions it has had a toll on him and he feels this is the time for him to step down. quite a few vacancies _ time for him to step down. quite a few vacancies in _ time for him to step down. quite a few vacancies in england _ time for him to step down. quite a few vacancies in england click - time for him to step down. quite a few vacancies in england click it. time for him to step down. quite a few vacancies in england click it soj few vacancies in england click it so et al. be interesting to the deal with this. and all change the premier league club burnley. a shock announcement and that sean day should has been at burnley for ten years, the longest serving manager in the premier league, he has seen them relegated at the end of 2015 and brought them back up to the premier league and there have been a funereal message is when they have almost been relegated over the years —— a few near misses so that has been some scathing reaction. chris sutton called move any tick and gary lineker used the worst want and gary lineker used the worst want and you will have to read that onto and you will have to read that onto a thumb because i cannot repeat it and he said sean dyche did a brilliantjob but let's look at and he said sean dyche did a brilliant job but let's look at why this happened, burnley are four points off safety with eight games to go, only 1a times this season which leaves them facing relegation unless they can perform a medical. the chairman said this is incredible difficult but change is needed. premier league managers do not usually get much time and many chances so that is why sean dyche was something of a rarity being at the club for a decade and that leaves liverpool managerjurgen leaves liverpool manager jurgen klopp leaves liverpool managerjurgen klopp as the premier league's longest serving manager. no one is in who will replace sean dyche has been given but we will keep you updated. t been given but we will keep you u dated. ., been given but we will keep you u dated. . ., ., ., ., ., been given but we will keep you udated. . ., ., ., ., ., updated. i am from near that area so ma be i updated. i am from near that area so maybe i should _ updated. i am from near that area so maybe i should hand _ updated. i am from near that area so maybe i should hand in _ updated. i am from near that area so maybe i should hand in my _ updated. i am from near that area so maybe i should hand in my interest, | maybe i should hand in my interest, expressed my availability. much as i know almost nothing about this game but i know lots of people will be very interested in who comes next at burnley. it very interested in who comes next at burnle . . ., , very interested in who comes next at burnle . , i. very interested in who comes next at iturnley-_ thank- very interested in who comes next at burnley._ thank you. | the duke and duchess of sussex met the queen yesterday afterflying into the uk. the couple stopped at windsor on their way to the netherlands, for the invictus games. our royal correspondent sarah campbell told us more about their brief visit. it was certainly a flying visit. they were in and out of the country before the media got wind of it. it appears they flew in on wednesday evening, stayed overnight at the cottage in the grounds of windsor castle and made their way sometime yesterday to windsor castle itself and had a meeting with the queen which was confirmed by their spokespeople later in the evening. this is the first time the couple together have been in the country since 2020. meghan has not been back in the uk since 2020, harry was back for the unveiling of the statue of diana and the funeral of prince philip back in april last year, almost exactly one year ago. there has been a lot of water under the bridge since they left, the oprah winfrey interview, recently ongoing, this high court claim against the home office brought by prince harry talking about protection, it was said in court he does not feel it is safe in the uk to bring his family across. clearly they felt that a stop—off on the way to the hague to the invictus games was something they could fit into their schedule and that's what happened yesterday. a former british national who joined the islamic state group in syria, has been found guilty in the united states of hostage taking and conspiracy related to the murders of four americans in syria. el shafee el—sheikh was part of an is militant cell dubbed the beatles by hostages because of their british accents. the british aid worker david haines was one of the hostages who was executed by the islamic state in 2014. his brother mike has been speaking to our reporter steve swann. david was my little brother. hejust had this charisma around him. he was a bubbly person. he drew people in. when david started talking with refugees, he changed. we saw for the first time a sense of purpose. he had found his calling. then you heard the news he'd been kidnapped. yeah. i thought it was the worst day of my life. having to tell my mum, our mum, our parents, our family that he had been taken. ijust couldn't imagine anything worse. we firmly believed that once isis knew that they had british and american hostages, they were dead men walking. itjust took them 18 months of hell. and then you heard the worst news possible. can you tell us about that? so the 13th of september was the night when my family were torn apart. just a few days before hand, i had moved most of my family to my home. we had people sleeping on the couch, on air beds, all sorts of places. the 13th of september was a beautiful day. we filled it full of family love and laughter and hope... we hoped my brother would come home safe. there had been an outcry around the world calling for the release of the humanitarian worker called david haines. we had all gone to our beds. i'm sat on the side of my bed undressing and my phone began to ring. it was three minutes past 11 at night. and there was a blackness inside of me. because i knew it was the call that i had been dreading since day one. it was my team leader here in london telling me that david was no longer with us. and i gathered my family together. i took my mum's hands... and told her her son couldn't be hurt any more. that was truly the worst night of my life. terrorists with any attack are looking to spread hatred. their actions of murdering my brother were about hate. and if i hate, they win. they hold a big part of my life because i have hate for them. so i will not give them hate. david's remains lie rotting in the desert somewhere. he was not brought home. and for me, that is not important. because david walks with me still. two stories from the natural world to end this hour — researchers have warned that the cactus family of plants is facing a severe threat from climate change — despite the ability of many species to endure heat and drought. a study of more than four hundred cactus species concluded that sixty percent could be at greater risk of extinction by the middle of this century. the authors note that despite their reputation for being hardy survivors many cacti depend on very specific environmental conditions, which are likely to change as the world heats up. many of the prickly plants are already endangered because of human activity. and a bit of news that's come from germany, where the berlin zoo celebrated the birthday of a rather special gorilla. her name is fat—ou and yesterday, she turned a remarkable 65 years old. the average lifespan for most western lowland gorillas is roughly 35 to a0 years. so, the zoo presented fatou with a cake made of rice and fruit. for many of us the weather throughout the eastern pleaded is very decent indeed with one sunny spells, today been the warmest day of the next few but this headline does not tell the whole story, in fact many western parts of the uk are often cloudy especially around coastal areas because of a weather system on top of the british isles giving some rain, murky and drizzly conditions around coasts. 15 and plymouth but inland and excess of 20 and look how cool it is on the north sea coast in aberdeen. in the north west of the uk thicker cloud and showers through today and look loud around western coasts, relatively mild overnight, 6—8, may be cold a falling to fourfrom mild overnight, 6—8, may be cold a falling to four from the sky is clear and east anglia and tomorrow do it again, western areas cloudy but the vast majority of us and for some warm spells of sunshine so if you are stuck underneath the cloud today and tomorrow you are amongst the few, many are enjoying the fine weather. looking at the forecast into sunday, there is a breakdown and the weather happening, the blue as rain a weather front moving across ireland which means we are in for some wet weather and northern ireland and some western parts of england, wales and scotland so here is the forecast, easter sunday outbreaks of rain reaching at least the west of northern ireland, eventually reaching western scotland, may be nudging into pembrokeshire and possibly cornwall but look at the bulk of the uk enjoying a relatively warm and sunny sunday then on monday i think most of the rain will have fizzled out but more cloud and rain spreading to the north—west so breezy conditions and certainly some rain or showers and certainly some rain or showers and western parts of scotland, again the bulk of the uk enjoying sunshine so a bit of a mixed bag. this is bbc news ? welcome if you re watching here in the uk or around the globe. i m geeta guru—murthy. our top stories: russia says it's hit a factory near the ukraine capital kyiv that produces anti—ship and air—defence missiles — and warns it will intensify its missile attacks. it's after the sinking of the flagship of russia's black sea fleet. ukraine claims its missiles destroyed the moskva, but the kremlin says it was damaged by a fire onboard. meanwhile, in an exclusive bbc interview in his war bunker, ukraine's president says continuing attacks from russia are damaging chances of a peace deal.