Massive fines if they dont act. Im Still Standing better than i ever did. Brexit ended visa free travel to the eu for musicians. Now, eltonjohn tells us why it will hit so many young performers. And coming up, a Hollywood Gladiator sends a surprise Birthday Message to a british sailor taking part in a round the world yacht race. Good evening and welcome to bbc news. The Prime Minister has thanked all those who have helped the uk to reach a milestone in its Vaccination Programme ten Million People have now received a first dose. But borisjohnson also issued a warning, describing the levels of covid 19 infections as alarmingly high. He said that while there was growing evidence of the effectiveness of the vaccines, the government needed more data before considering any relaxation of covid restrictions. Heres our Political Editor laura kuenssberg. Sleeves up, syringes ready, vaccine in army medics filling this Church Hall In Chingford where there used to be bingo nights and dog training. Theyd done 400 by lunchtime. No hanging about. Obviously, a lot of people are shocked that were here. But then theyre also so thankful that were here. And itsjust nice to feel appreciated. Theyve literally come out of their house just for this vaccination, and theyve literally turned around and said, look, we cant thank you enough, and i cant tell you how much that resonates with each and every one of us. Now, the whole country has hit the 10 million mark. We have today passed the milestone of 10 million vaccinations in the united kingdom, including almost 90 of those aged 75 and over in england. Whether a church hall, a town hall, a temple or a car park at a leisure centre, there are more and more places right around the country where the vaccine is on offer, helping to loosen the grip the pandemic has had on our country for such a long time. But the vaccine programme, astonishing though it is, is not a route out on its own. Are you sure the vaccines will work on all the variants, Prime Minister . Hes accused of leaving a gap where more dangerous versions of the disease could creep in. Borisjohnson promised travellers arriving from 30 at risk countries would have to stay in hotels at airports for ten days, but theres no date for when that will start and labour wants every country on the list. With new variants in the country, our schools are shut and our borders are open. 21,000 people come into this country every day. The Prime Ministers new Border Arrangements are still weeks away from being implemented. This queue in a london suburb isnt for the vaccine but extra testing, to clamp down on a new variant of the disease from south africa thats already here, and the government admitted today at least 20,000 people instructed to isolate with the disease arent doing so. Terese came out for the first time for many months for her vaccine and understands why others might break the rules. There are people still going to work because they need the money. Theyre not doing it to deliberately say, i dont care. And in lockdown, 28 year old nish has become the breadwinner, but he reckons its hard to force people to stay at home. I think the majority of people will not self isolate because of lockdown fatigue. And also, id say not clear messaging from the government. Was it clear today . Can you give a firm date for when Hotel Quarantine will start . And will you offer more help for people who just cant afford to isolate . If not, arent you leaving two big holes in our defences . We have among the toughest Border Regimes now anywhere in the world. Were restricting as much as we can any risk of importing new infection into this country, without totally secluding the uk economy. But nhs test and trace is reaching 90 of contacts, and the vast majority of them are doing the right thing. The Prime Minister did confirm he wants england at least to leave lockdown as one, even if the rest of the uk might follow different timetables. But while theres jubilation at the vaccine, there are still obstacles ahead. Its too early to take a break. Laura kuenssberg, bbc news. Astrazeneca and Oxford University say they aim to have a Next GenerationCovid Vaccine ready for use in the autumn should it be needed. The newjab will help to give protection against some of the variants that have been discovered recently. Today, the health secretary, matt hancock, said Research Suggesting the current Oxford Astrazeneca vaccine may reduce the spread of coronavirus is superb and will help us all to get out of the pandemic. 0ur Medical Editor fergus walsh has more. The scientists at oxford who created the astrazeneca vaccine are continually monitoring how coronavirus is evolving. The current vaccine is thought to give good protection against new variants, but they are working on tweaking the jab to make it future proof. The scientist who is leading the Research Says it is relatively simple to redesign the vaccine. Its not difficult to put a different Antigenic Insert into the vaccine. So we dont want to panic and say that we must have a new version of the vaccine now, but on the other hand, we are getting prepared, so that if it turns out we do need a new version, it will be ready to start using it. Those on the oxford vaccine trials were shown to have 76 protection from a single dose, which lasted for three months, rising to 82 protection with the second shot. It is also the first time a Covid Vaccine has been shown to reduce transmission of coronavirus. Those immunised were much less likely to test positive for infection, cutting the risk of them passing the virus onto others. That is the vaccine, but what about those who have actually had covid . They want to know how long they may be protected against subsequent infection. At least part of the answer may come from a study involving 20,000 people who were sent home testing kits like this. Like the other 20,000 volunteers, i was asked to send off a few drops of blood, every month, to a lab. Scientists at uk biobank found that 88 of us, nearly nine in ten, who started off with antibodies still had them six months later. I think these findings are really good news, because it does suggest that people who have been infected with the virus may have some degree of protection against another infection for some considerable time. What we would really like to know next is, how long does this Natural Immunity last for beyond six months . Scientists think vaccines are more likely to offer stronger protection than natural infection, so a key message is to get immunised, even if you have already had covid, to boost your immunity and maybe protect others. Fergus walsh, bbc news. And this evening, Birmingham City council says its ramping up testing in two areas following the discovery of the South African variant. The council is urging residents in the Frankley Great Park and northfield areas of the city to take a covid pcr test this week, even if they are not showing any symptoms of the virus. The latest Government Figures show a continuing fall in new coronavirus cases. There were 19,202 new infections recorded in the latest 24 hour period, which means that on average, the number of new cases reported per day in the last week is 22,396. Across the uk, an average of 32,851 people were in hospital with coronavirus over the seven days to monday including suspected cases in wales. 1,322 deaths were reported thats people who died within 28 days of a positive covid 19 test. On average in the past week, 1,064 deaths were announced every day. The total number of deaths so far across the uk is 109,335. Now, lets look at the Vaccination Roll out. 374,756 people have had their first dose of one of the three approved covid 19 vaccines in the latest 2a hour period. As weve heard, that takes the overall number of people whove had their firstjab to 10,021,471. With me now is professor simon kroll from Imperial College london. He is also a member of thejoint committee on vaccination and immunisation thats the body which advises the uk government on vaccination schedules and safety. He is speaking this evening in a personal capacity. We thank you very much, professor, forjoining us. First of all, your reaction to the surpassing of the 10 million mark for first doses . I think it is absolutely brilliant. The early stages, when things were not going so quickly, it would have been almost unbelievable to think we were going to achieve this. We are on track to get to the government target of reaching the first four priority groups by the bill of february and i think it is a marvellous result, an absolute tribute to the fax natures, including the army, who have made this possible vaccinated. And of course the people turning out to have their vaccine. Course the people turning out to have their vaccine. There has been a lot of talk about have their vaccine. There has been a lot of talk about the have their vaccine. There has been a lot of talk about the astrazeneca lot of talk about the astrazeneca vaccine in particular, infinitely Different Countries taking different announce of time to give the 0k, ctrl likes whistling going different routes to other countries, worry about its efficacy in the over 65 group. What is that your take on all that debate and argument right now . I am sure there is a political dimension like this, and ifeel i am sure there is a political dimension like this, and i feel i cannot give any insight to that, but what i do see as a clinical scientist is the data. The data that andrew pollards group, the oxford Vaccine Group, the oxford part of the vaccine and ever, they have shown to our satisfaction that their vaccine is effective, both in adults under 65 and in order adults older adults. There is some lovely did wejust hearing older adults. There is some lovely did we just hearing now older adults. There is some lovely did wejust hearing now in older adults. There is some lovely did we just hearing now in the lead statistician� s paper, describing a further analysis of the Clinical Trial and showing that the Vaccine Levels of antibody and also the efficacy last right out to the 90 days that we have suggested would be the limit to follow in the uk. And there is not any waning out at that time, which is what we anticipated to be true, but its very good to see the data. We to be true, but its very good to see the data. See the data. We also talk a lot about transmission, see the data. We also talk a lot about transmission, dont see the data. We also talk a lot about transmission, dont we . | see the data. We also talk a lot about transmission, dont we . Tell us more about what this means any of this. ,. , us more about what this means any of this. ,. , this. Transmission is the passing of the virus from this. Transmission is the passing of the virus from one this. Transmission is the passing of the virus from one person this. Transmission is the passing of the virus from one person to the virus from one person to another, and there is a reasonable inference if somebody is ill with covid, particularly if they have got Upper Respiratory Tract symptoms coughing and sneezing and chest problems that they will be a bigger risk to passing the virus around, but we also know a lot of people will carry the virus without being particularly unwell, or even without being unwell at all, and the question is whether they constitute a continuing risk or a significant risk for passing the virus on or whether any of this is modulated by the vaccine, and that reanalysis that the author Vaccine Group or just publishing shows quite clearly that the risk of carrying the virus, as tested by the pcr test, a very sensitive test for the virus, that risk is greatly reduced by having had a dose of vaccine, which is extremely good news because it gives us, as it were, a way out of this pandemic, not only do we want to reduce cases and are primary him as to produce fatal cases, but we also want to reduce the reduce comic reduce the risk of that virus passing person to person and it looks at the astrazeneca vaccine achieves to that end at some point what about the variance at the moment . How worrying are they . All the evidence moment . How worrying are they . All the evidence we moment . How worrying are they . All the evidence we have moment . How worrying are they . All the evidence we have at moment . How worrying are they . All the evidence we have at the moment suggest the current vaccines are effective against the new variant. We cannot of course be sure variance will not emerge where that does not become a problem, but the good news, and we heard that in your package earlier, is that the vaccine companies, Astrazeneca Respeaking earlier, can quickly modify the vaccine. Notjust modify it to make it a future proof, i think the word was used, but also produce it in time. In a way, thats as much certainly as important as just changing the nature of the vaccine, making enough of it to give to people, and we are hearing is they should be able to make a vaccine if it was needed within months and have it was needed within months and have it ready to deploy. And thats very good news. It ready to deploy. And thats very good new good news. 0k, professor simon kroll, its been good news. 0k, professor simon kroll, its been really good news. 0k, professor simon kroll, its been really good good news. 0k, professor simon kroll, its been really good to good news. 0k, professor simon| kroll, its been really good to talk to you. And well find out how this story and many others are covered in tomorrows front pages at 10 40pm and 11 30pm this evening in the papers. 0ur Guestsjoining me tonight are the daily telegraphs chief political correspondent, christopher hope, alongside the Evening Standard columnist and times Radio Presenter and former labour Party Adviser ayesha hazarika. The headlines on bbc news ten Million People across the uk have now had their first dose of their Coronavirus Vaccination, giving them some protection against the virus, but theres a way to go before lifting restrictions. The oxford vaccine Scientists Say theyre already working on another vaccine to deal with new variants. A National Clap in celebration of the life of captain sir tom moore, who died yesterday as well as for health care workers. Sport and for a full round up, from the bbc sport center, heres chetan. Thank you. Hi there, good evening. Manchester city are back three points clear at the top of the premier League Tonight after a 2 0 win over burnley at the etihad. Gabrieljesus opened Gabriel Jesus opened the gabrieljesus opened the scoring, following Bernardo Silvas shot which came straight to him from nick pope afterjust three minutes at turf moor. Good start for city there and Raheem Sterling then got the second seven minutes before half time, wrapping up that win. Fulham hadnt won since they last played leicester in november. And that is still the case. James maddison set up Kelechi Iheanacho for the opening goal. And then just before half time, maddsion was again the provider, as jamesjustin made it 2 0 just before the break. Leicester are up to third for now. Fulham nine points from safety. You can look at it however you want to look at it, and i understood what the perception will be of my team and this team. 17 Football Matches to play and a team here that have beenin to play and a team here that have been in games, for sure been in games. Lets not look away from the fact we have played against a very good team, i think third or second in the league, they are, and we have got 17 games to go. We know what we need to do, there will be a clear focus on that and we will endeavour to do that. There are three matches currently being played. Everton, looking to bounce back from their defeat to newcastle, are currently 2 0 up against leeds at half time. Meanwhile, the champions liverpool are without their Goalkeeper Alisson tonight because of illness kelleher his replacement. That has kicked offjust now, as has aston villa and west ham. And in scotland, rangers are looking to further lead at the top of scottish premiership. Earlier, there were 2 1wins for motherwell and ross county. Southampton say their teenage midfielder Alex Jankiewitz was racially abused on social media. It follows his sending off in their 9 0 defeat to Manchester United last night. Its the latest in a string of such incidents. Southampton say theyre passing on all abusive messages to hampshire police. Preprations for the Australian Open tennis have taken another blow with more than 500 players, officials and support staff going into isolation. Its after a worker at one of the events