Capitals government buildings across this is led to the results of sundays parliamentary election being a no talent staff that has the latest from diskette people you can see behind me supporters and representatives of various Political Parties a number of which are members of the set up yesterday and what i said i guess they called the Coordination Council which represents around 8 Political Parties and theyve been making some pretty fiery speeches this morning so far theyre demanding all that theyre demanding that the president is impeached there demanding that. All parliamentary members come together for a meeting a session we had a parliamentary session yesterday but it was we understand only around 20 employees took part in that emergency session. White house adviser Stephen Miller has become the latest Administration Official to test positive for the covert 19 around a dozen white house officials have now tested positive including the president the virus has also spread to the Defense Department and a number of senior commanders are in isolation. Theres been fierce fighting of a nice as armenia and azerbaijan continue basso over the disputed nickel mccotter back region people in the territories main cities took shelter to avoid shelling from asa by jon yes by johnny saeed say media has also launched attacks on several regions. Facebook is removing accounts and pages promoting annan a us Conspiracy Group online post started 2017 the group claims u. S. President donald trump is battling an alleged child trafficking ring run by celebrities and government officials. Say you have lies news continues hinault is there to inside story. Not just the Republican Party but America Needs 4 more years of President Donald Trump in the white house then the outcome of this election will determine i believe the poorest of our country for generations to come live coverage of the Vice President ial debate on a. 3 virus hunting scientists win the nobel prize for decades of research into hipaa to see with millions of lives saved and hope for eradication why is there were being rewarded now and what kind of teach us about fight against covert 19 this is inside story. Hello and welcome to the program. Doha as the world battles and u. N. Deadly pathogen 3 scientists have been honored for their work on a virus thats above its people for decades hypnotized to see harvey alter Michael Holton and Charles Weiss are sharing the nobel prize for Medicine Research dating back to the 1960 s. Successfully identify the virus limited its spread and let effective treatments but as with the new corona virus theres no vaccine hepatitis c. It causes potentially fatal Liver Disease its transmitted through budget if you know its including blood disorder says while medical advances have improved our weapons against viruses political well is whats needed to defeat them the issues now are really not science anymore the science and hepatitis c. Has gotten to the point. We we dont really need better drugs than we already have we dont need better test than we already have but we need is the. Political will to eradicate it his fellow laureates professor vice believes its a likely hepatitis c. It will be eradicated by the double targets in 10 years his says the spotty because many countries have banned research on chimpanzees which is more effective than studies on rodents one of the challenges with the axioms is really sort of having a predictive model in which to you know sort of test your ideas and your vaccine candidates and. Certainly one of the aspects of that that is fluid process is slow that process is these are an ability to sort of use. Primate models for those kinds of. Efficacy us. So as you can probably glean from whats happening with the of the 19 vaccine efforts there are a myriad of different platforms that could potentially be. Used to develop a vaccine also against. Against appetite a seed need to actually take even one of the one that it takes to. Get it into the clinic is very difficult. Lets bring in our guests Stephen Griffith is an associate professor at Leeds University and of the Virus Division of the u. K. Microbiology society in east bourne philippa is a broke is an epidemiologist and scientist with the World Health Organizations global hip otitis program and joining us from stowe in the u. S. State of vermont is dr bob arnot former chief medical correspondent at n. B. C. New years welcome to the program stephen quite fascinating the long journey it took us scientists to understand the disease and also the swedish while academy to recognize their legacy yes thats right i mean ive worked in them to see for Something Like 20 years now and of course it was you know personal discovery back in 1909 so its probably a good time now to recognize that now we have these new drugs and different treatments for patients which is a fantastic advance and largely thanks to the Prize Winners that were talking about today philip are 8 the Swedish Royal Academy is known for taken with really some time before recognizing the work done by scientists is because theyre in this particular field you need more time to verify the scientific Scientific Research and its impact. Well i think this is very much what weve seen in that the whole history of the nobel prizes the pave the recognition comes long after the original work was undertaken but i think what we are now seeing that happened i did see is the direct different items of their accomplishments and identifying the causative virus in identifying a diagnostic test and then following that the the development of antiviral treatments the targeted have the time to see and so we are now being able to reap the full benefits and see the full outcome of that their their contributions and we now have these highly effective treatments. A diagnostic test that was able early on to immediately screen blood products and stop important transmission on the 3 of the virus but with the names of the 3 scientists all to houlton and dries came out i think the 1st suppressing among many people was basically that these people made some seminal work offend you get the impression that the achievement was somehow overlooked or overshadowed by others and this explains why i think it took the Swiss Academy the time to say finally you know what its about time to all of these people i thought i saw the as a these are very very good you know it just has so many things going on and so much of what your biology is stunning advances was sort of left in a backwater for many years ago you know what they did back then great done in a very short period of time now is you know much sequencing fantastic speed but you know nobel prize when i was in the last i did and they did said you know were very careful you know we really want to make sure that we get this one right and you know its attributed but as a lot of us leave though our lives is very researchers and medical doctors are proud cast journalists and we have little achieved. Its all way along the way that will make us feel good about our careers these people were out in that dark me they were larry having no idea theyd ever find anything and what are your devote your lives to a cause like that. Those many years that much doubt we ever find anything i think thats really the test the nobel and remember too that 1st day they knew they were selling the bloody no idea what it was and finally the 1st richer 5 stuff finds that 2nd one then finds the antibodies thinking about the test and then the 3rd one years later then finds the therapies are very long strength but you porton so it has which is so critical is that there are still 17000000 people in the world today were back to have a time silly and there are nearly 400000 deaths which is utterly and completely inexcusable given the availability of drugs which are just too expensive for them so many parts of africa nation stephen we all love those discoveries the make the world a better place to live in and what is interesting about these 3 scientists is that when you look of them they were working in different wells with different perspectives all to show that the blood for the hepatitis patients could transmit the disease and then horton isolates of the gene it genetic sequence as weiss provided the final bit of the puzzle by showing how the virus alone could cause the disease i mean quite remarkable how separate works brought together that discovery that made an impeccable change in the world. Thats right and it has. And each of these discoveries preceded more another and they will try to. And it. Speaks to the difficulty it working but its been secure a lot less i mean even. Since. Something like 1617 years before getting growth in mars and so since then which wouldnt have been happening apart from these these 3 is going to raise thats when a Drug Discovery process really kicks in and the Drug Discovery against this virus has been. Transferred to the successful but also very compressed period of time considering other viruses that we sayn and so these these terrorists really are. A tremendous success around cigar discovery but its really as we just not the finest. People infected with this iris we have a disproportionate and that is less well countries and we really still do need a vaccine across market hounds working very hard now. Philip why is it why is this fight far from over because when you look at places like egypt. And where the infection rate is really increasing through the year why why is it of that particular stage. Well i think we now have this incredible 2 of the highly effective treatments that are available of affordable affordable price but what needs to be in place to mount a response you need a National Plan you need a lavar tree infrastructure you need a testing infrastructure she need a supply chain you need a prick youre meant strategy you need to train the Health Care Workers so this is what it takes to fight an epidemic and of course we many of the same principles apply are applying with with with coverage and i think many countries have stepped up very well and there are some champion countries one of which you refer to egypt but also a row under in georgia and mongolia. As well as some high Income Countries including sort of australia from. Scotland england and others that have her recognised that this is a Public Health problem and have mounted a response and i think its not all about the drugs the drugs have been found with the catalyst to enable the response and what was also important was the rapid decline in the drug prices and it took 1520 years for us to see this in the h. I. V. Weald but in a very short space of time from a all time high so for almost a you know a 100000. 00 for a treatment very quickly down to a 1000 and then 500. 00 for a 12 week treatment course im now less than 50. 00 that is quite phenomenal but all these other mechanisms need to be put in place and the testing and the diagnosis is extremely important having high quality low cost diagnostics and being able to make it simple and straightforward and the other. Important thing is we dont need specialists to be the only wants treats he notes this is a very straightforward very well tolerated regimen and so as we learned with hiv were to scale up and get people access to treatment we need to train Frontline Health workers on the simple steps to administer the treatment so i think its when all these things come together as they have done so well in egypt which has screened 60000000. 00 more than 60000000 and treated more than 3000000 these are the examples the the models that other countries need to be following but of this comes against the backdrop of a somber moment where humanity is grappling with covert 19 and everybody asking the same question when are we going to find a vaccine but of the same time when you look at the time that took all those 3 scientists people are saying oh no we dont want that to happen now we dont want to wait for 30 years to find a vaccine for covert 90. Well you know its its quite interesting i thought the statement from the World Health Organization there was as elegant as i have and eloquent as ive ever heard anybody on television in terms of of Medicine Health care you know with coded the World Health Organization was unfortunately funded by the by the u. S. And i think what weve just heard outlines why its so critically important for the u. S. To stay in the game and that funny because of the intricate balance and dance that it takes to be able to train Health Care Workers and get testing up get into you know places like brody that you know may have parts of the country that are still in civil war i mean its a very tough thing to do is all of this infrastructure in training the takes that initial work really puts into play now what is interesting is you know you see with the president just last night he was taking rendez of air which was developed for hepatitis c. So hes the beneficiary of all this work and you see the tremendous speed you know that there are now Something Like 140 vaccine candidates there probably 7 or so that are now in stage 3 trials of producing lots and lots of in a body of present had a new therapy for a comic over general on multiple antibodies and just to make it clear you know when you give somebody a vaccine lets say that this is the vaccine then you develop antibodies to whatever its presenting this case is the spike virus well what this for general treatment does is it gives you premade antibodies is if you have the vaccine or as if youve taken some serapis already been affected you give that to somebody it may may may be why the president so long now is ok so has a troublesome course before really find out what. Does that the great 8 i think here youre saying how action in terms of all of them what your biology is really the you know the infin of this work that was done by these tremendous researchers before we continue this. Have a look at where do we stand when it comes to the hunt for kovan 1000 vaccine vaccines can take years to be approved but its hoped some being developed for coping 1000 could be available next year the vast majority are still in the preclinical stage being tested on animals not people about 40 are in phase one where given to any one full of people or face to where they are tested on hundreds face 3 is reported to have 11 promising prospects where thousands of trial patients receive the drug to confirm its safety and check for any side effects vaccines developed by the Pharmaceutical Company astra zeneca in conjunction with Oxford University and another by u. S. Biotech firm would earn a lot of stage 3 chinas given limited approval for use of a vaccine developed by sign of back after initial tests on soldiers and president Vladimir Putin gave the go ahead for a russian vaccine in august before phase 3 testing had human begun Stephen Michael horton is also part of a team working to produce vaccine for covert 19 and this is a white house or his said that basically its about time to focus on viable or g. Immunology and if factious Disease Research thats the only way out for us to be able to crack the code of cove in 1000. 00. Sure i mean i think its worth saying that a vaccine against our side hepatitis c. Actually part difference concepts are vaccine against Something Like. The National Virus its quite different in the way theyre very much more variable. As a sort of chance very intensive but of course what were seeing with with with sars is the race to get that done very quickly is a necessity however i think we need to be absolutely certain the outcomes are a randomized controlled space treaty that the vaccines that do effects of the use and the Wider Population are safe and our education and our what exactly want to do and whether thats setting high risk. Medicine the problems one understands so i think we are in an unprecedented rush and not rushing sounds of more has less russian sense of tremendous achievement to see some of the outcomes. Philip i mean this cove in 98 has been a wake up call in a way or another for us and for the community for for people like yourself and this is raising a concern among people basically saying that its about time for organizations like the World Health Organization to redirect efforts into investing more into until viral drugs because the next pandemic could be more devastating like over 1000. 00. Thank you i mean i just like to pick up on one other point i mean clearly the science has been absolutely fundamental to the Vaccine Development and its just you know gonna a real back to that which is important but we mustnt forget about access that you know ultimately we need to have a system in place that is going to allow where the vaccine is where the greatest need is the vaccine is made available so i think the initiative the target show has established kovacs for a a consortium to ensure that theres full cost of where the need is going to be and how to enable vaccines for the low and middle Income Countries hi