a global health crisis cardiovascular disease that's our number one killer already o.c. the hardest part is just the discipline we think of the fact that there really isn't the same if we throw that sugar increased risk factors this is a problem you know i visit time on old is you. again you're watching a reminder of our top stories this hour police have released a body camera video showing victims flame the last vegas mass shooting detectives say stephen paddick modified attack rifles to increase their rate of fire and the sixty four year old set up cameras outside his hotel room to watch for police procession m.p.'s in catalonia are meeting for the first time since sunday's disputed referendum that discussing what's next in their move to break away from spain hundreds of thousands of catalans went on strike in response to the national police's attempts to crackdown on the vote. turkey's president. is in tehran where he's met iranian president has an rouhani he's expected to meet the supreme leader ayatollah common name during a visit to one told turkey's parliament on sunday he expects to agree a deal with iran on how to respond to last month's kurdish referendum in iraq. the u.s. defense secretary has contradicted president donald trump on whether to abandon the iran nuclear deal james mattis says he believes the deal brokered under the obama administration is in america's interests trump is expected to decide in the coming days whether or not to hold up the deal he has repeatedly called dissolves patrick o'brian reports it was a simple question that greatly complicated the understanding of what the trump administration thinks about the iran nuclear deal do you believe it's in our national security interest at the present time to remain in the j c p o a as a yes or no question yes senator i do that doesn't seem to be where his boss is after all president donald trump took his time on the world stage to say this frankly that deal is an embarrassment to the united states and i don't think you've heard the last of it believe me. the president said he's made his decision his secretary of defense says it's still being debated but mattis made clear what his advice is the point i would make is if we can confirm that iran is living by the agreement if we can determine that this is in our best interests then clearly we should stay with it i believe at this point in time absent indications to the contrary it is something the president should consider staying with but that's not what the president promised on the campaign trail and he is still facing strong lobbying from those against the deal comes from certain circles in the republican party it comes from the israeli government not so much the goal but from netanyahu himself the israeli professional elite the civil servants the military they understand perfectly well that this agreement is a useful agreement in postponing any real challenge from the iranian nuclear program trump often says he respects his generals will find out by the next deadline tobar fifteen if that extends to the iran nuclear deal as well particle al-jazeera washington a motorbike has exploded in paris just outside the office of the jordanian military attash a jordanian embassy has confirmed the explosion saying it does not believe it was intentionally targeted no injuries were reported. well the french parliament has a has voted to adopt a controversial antiterrorism bill that will bolster the powers of the security forces extra powers for police and intelligence services under a state of emergency will become permanent critics warned they threaten civil rights but security forces argue the law is needed to protect the public. reports from paris. a majority of m.p.'s passed the new counter-terrorism law that incorporates many of the special powers given to the police under the state of emergency the interior minister says it's a way of combating an ongoing threat. we are still in a state of war even if i saw my have suffered some military defeats more than two hundred people have been killed in attacks in france in the past two years in mass a people paid tribute to the latest victims two women killed in the city's train station on sunday under the new law police can raid homes and arrest suspects without warrants and place people under house arrest without a judge's order rise ation while the government says that the new law will protect people critics say gives the police far too much power and will lead to human rights abuses they say france will be under a permanent state of emergency you know. suddenly we find ourselves with a law which integrates the tools of the state of emergency but without the country being in exceptional circumstances. it's a prospect which frightens tony a few days after the paris attacks and twenty fifteen police raided his house during the night terrifying him and his young children suppose he supposes. i found myself on the floor face down hands tied my children and wife taken to the back on the shouted where are the weapons. placed under house arrest until a court declared his innocence he believes he was targeted for being muslim and belonging to a shooting club secure fulfullment this was a lot closer if you shoot for sport and you are a muslim it's not acceptable it was before the attacks but now it's assumed you are a terrorist. the government's due to lift the state of the mergence the next month but only worries that the new law will encourage discrimination and lead to other french people having their lives turned upside down natasha butler al jazeera paris . the un human rights committee says the abuse of range of women and children in myanmar could be crimes against humanity the committee is calling on myanmar government to stop the violence and allow proper investigations over half a million a ranger have fled me n. miles were high and state after targeted violence escalated in late september the un has called it the world's fastest developing refugee crisis and there's growing concern as well over the health of ranger living in bangladesh as makeshift camps hundreds of people are sharing single toilets and contaminated water supplies will help workers fearing a cholera outbreak would easily spread via cherry has more from cox is bizarre. no one can describe the condition of some of this temporary refugee shelter built and to prolong area thousands of people concentrate in one area and scratching it up to thirty a degree there is very few left raw sewage floating in the drainage there is no sewerage system no fresh water system very few fresh tubas are set up which is some help but the international aid agencies are warning that you need to be far more number of electrons and fresh water source in this camp one bangladeshi and you say that there are three hundred twenty seven person using one letter and that's a very dissimilar condition now we spoke to a lot of the doctors who are running this mumbai training and different camps most of the doctors told us the majority of the patients are saying have diarrheal disease skin infection and respiratory illness with high fever most of the patients are women and children unless there is a long term strategy chucked out by the government international donor agency there is a clear danger of cholera and dysentery epidemic spreading out in this camp the international coordination group is sending about one million or a vaccination people that should help the situation to a bit most of the refugees are not going back very soon that has to be a long term strategy once the media focuses on out of this refuges there's a clear danger of aid flow into this camp will slow down. when hurricane matthew hit southern haiti year ago hundreds of people died and ninety percent of the area was devastated daniel shriner is in port au prince now with more on the rebuilding efforts haiti the poorest country in the region lives a precarious existence often rebuilding from the previous natural disaster when a new one strikes hurrican matthew struck the southwest of the country killing more than six hundred people devastating ninety percent of all properties and causing two billion dollars worth of damage something like twenty percent of the country's g.d.p. roads were impassable bridges were destroyed it often took rescuers days to reach the stricken area many of those regions now have been rebuilt roofs have been replaced the bridges have been replaced but the government relying mostly on foreign aid says there's still more needs to be done the recent spate of hurricanes that hit the caribbean mostly bypassed haiti and for that there was a huge collective sigh of relief but the people here know that the next one is just around the corner but they won't be reading and then there will be massive devastation. it is sixteen years since the first manmade object was launched into space sputnik one was a cold war propaganda coup for the soviet union as far as space race with the u.s. to send a man to the moon and one thousand four hundred satellites orbit the earth today. our big football clubs are tuning into the power of social media to help build their brand now imagine a football team put together on social media that's what's happening in the u.k. . reports from london. their first ever game was managed by one of english football's biggest names rio ferdinand and one huge huge plan to change your name but this isn't a premier league team this is rebel f.c. . the love of football is what unites this alliance with social media influences and bloggers. the grassroots movement mixes football with entertainment aside from life matches good says of behind the scenes fan punditry pranks and challenges they make up most of their online content or start a blow to the first video on you and i went really well from there and i continue to put on instagram twitter where all fans are following and keep up today. and its own styles who came to see their idols one person at this event in london i want to meet today in the site and have lunch see you choose old styles while the football teams regularly engage with their fans online this is also a chance to meet them face to face. share the stage. and pose for a selfie there are ten facial media football team in the case and for years following is growing by the day but in this interaction here with the fans offline and online but the football team stays behind their growing. and as one of the world's leading football freestylers tells us a fantasy is key you can actually almost make you want to see us play next and they can actually have their own playing and as soon as you can engage with the audience that's what takes it to the next level while social media football team say they are looking to replace. traditional football they do believe their biggest appeal is relatability especially at a time when fans are becoming increasingly frustrated by how commercialized and non-personal professional football has become one story actually easy to get into like one of those you tube like that which on the life of the teams was a lot like for me this is a big market is always going to this is going to go to be the largest crowd for a football match with nonprofessionals and by the looks of it these amateur footballers have found a winning formula to kick the ball and their businesses in the right direction so to al-jazeera london. this is to get a round up of our top stories u.s. police have released the body camera video showing victims escaping the mass shooting in last vegas detectives say stephen paddick modified attack rifles to increase their rate of fire the sixty four year old set up cameras outside his hotel room to watch for police i'm not aware of any transmission but there was cameras there was cameras located in outside of the world and inside the room along with the farms. i don't know what the specific numbers you know. or go into is a big he was looking for anybody coming to take him into custody process session employees in catalonia are meeting for the first time since sunday's disputed referendum that discussing what's next in their move to break away from spain that follows a day of strikes by hundreds of thousands of catalans in response to the violence by spain's national police during the vote turkey's president tiber duenas touched down in tehran to meet iran's president has an rouhani and supreme leader ayatollah ali from an eight to one told turkey's parliament on sunday he expects to agree a deal with iran on how to respond to last month's kurdish referendum in iraq. a court in turkey will deliver a verdict in a major trial linked to the failed coup in two thousand and sixteen forty seven people including many military officers are accused of trying to assassinate president prosecutors are seeking a life sentences on the night of the coup two policemen were killed in the hotel world one was staying president says the location was bombed minutes after he left the u.s. state department has ordered the expulsion of fifteen cuban diplomatic staff and has given them seven days to leave the country that comes after the u.s. reduced its staff at their embassy in cuba citing unexplained injuries to american staff there cuba's government denies accusations it was involved and called the u.s. response reckless and hasty top u.s. generals accuse pakistan's main spy agency of links with armed groups has denied that claim those are the headlines techno is next it's not just phones contributing to samsung's bumper profits if we look at the u.s. economy the moment it does seem to be in pretty good shape up until around two thousand and five greek debt levels were basically stable we bring you the stories that are shaping the economic world we live in counting the cost at this time on al-jazeera supersized. scientists around the world make a desperate plea to stop an epidemic of obesity. but now new research goes beyond that to reveal a risk that could be even greater. techno expose the science of. this is a show about innovation and change. we're going to explore the intersection of hardware not my doing it in a way this is a show about science i find. sugar it's the ingredient the bring smiles to the faces of children around the world health experts agree in moderation it's an essential part of nutrition but it's also becoming the number one culprit in a global health crisis according to the world health organization consumption of free sugars especially sugary drinks is behind a large increase in cases of obesity and diabetes. in two thousand and fourteen one in three adults worldwide were reported to be overweight. by two thousand and fifteen data showed forty two million children under the age of five overweight or obese. forty eight percent of those children living in asia and africa. in mexico the problem is even worse. according to a study by mexico's national institute of public health seventy percent of adults are overweight or obese mexicans drink more than anywhere else on the planet one hundred sixty three liters a year. that's forty percent more than the average american consumes one hundred eighteen. in two thousand and fourteen mexico imposed a tempest and excise tax on those drinks. the. mexico. calling for global sugar tax consumption sugary drinks. have. a growing body of research just behind. in two thousand and fourteen harvard university i did sugar intake. look to. not just in drinks finding a significantly increased risk of. such being conducted inside the davis california may be the first to show cause and effect the project under the us national institute of health put subjects' on a highly controlled sugary diet for ten weeks then measures the effects of that added sugar already. on. the cutting edge research is being done at the department of molecular bias science school at the university of california at davis professor. invited techno inside for the final face of the trial. picks up the story behind the science of sugar. it's early in the morning for the small group of college students they're not here for a class they are subjects in one of the most advanced sugar studies to date. in just a few moments they will each undergo a magnetic resonance imaging exam doctors are most interested in what's been happening inside their bodies over the past ten weeks. hey guys good morning morning and really guys are up bright and early for your standards so really get you guys dressed and it's going to who's who's up first. this is day seventy four work. the final day of the study and benjamin lamb angela osborne and lore are ready for their m.r.i.'s. dr john mcgann is one of the world's leading specialists in diagnostic radiology he is supervising the imaging part of the trial. lore is a senior at u.c. davis he's a science student who decided to volunteer for the summer study if i remember. it's. like the other subjects more had a previous scan start of the trial doctors captured the before image of his abdominal region this morning they'll get. it so it's quite it's very it's. something i've never done before and i think through this two week i really don't know about myself. and this took. knology is being used to chart what happens to internal organs when sugary drinks are consumed those results cannot be calculated by scales and are not visible to the naked eye that's where the m.r.i. comes in dr mcgann showed us exactly what he's looking for in the scan the key item that we're looking at in this study is this structure here sort of a little darker or greater structure which is the over what we're trying to do we do need different m.r.i. sequences and then later on we go ahead and we calculate the amount of fat with the livable pre and post study and why is liver fat porton here liver badness important because it's sorta helps and regulates a lot of different things within the body glucose metabolism it also regulates the monitor try to list price that we have circulating within the body so it's actually sort of a clearing agent you know for a lot of different things here produces cholesterol so there's all sorts of different things the liver does and in order to really get a sense for this particular subject you have to look at the scans exactly and we look at that both at the libbers so we calculate well how much bad is there in the liver before we started this study and then all this and we can go back again at the end of this study and we know exactly what our bad calculations are how much fat is there at the end of this study and then we compare those two is it decreased is that the same or said increase to many of our study patients this latest sugar research should help professor stan hope and her team answer to important questions about sugary diets dr stand up tell me about the sugar study that you have going what specifically are you looking to find out the first question is. does sugar cause undermine our health. that by that i mean increased risk factors for cardiovascular disease so such as what for example cholesterol big that's the most obvious one does cardiovascular disease increase when you consume a high sugar diet even if you don't gain weight is the sugar have a specific the fact that other foods such as bread mill rice do not have now your your current study is focusing on subjects that are relatively young and healthy why if we prove in a relatively young healthy. person that sugar increases risk factors with. have shown that this is a problem. stan hopes team will follow a total of sixty subjects over the course of ten weeks the group techno was permitted to follow are all young mid twenty's and apparently healthy they are excited to see the finish line and exhausted from their dietary regimen this study was hard food wise because being around your family. there's always fried chicken and mashed potatoes and you have to stick with it to be tempted to. eat other food you're not supposed to be to not supposed to so i would say the hardest part is just the discipline it's been quite a challenge for me. because i love for. people who likes to cook. whenever i smell their cooking i just want to get their food. through the course of the study researchers strictly controlled the food consumed by each subject specifically the amount of sugar and calories in their diet the study is a single blind study meaning only the scientists know who is getting what one group of fifteen subjects will be given beverages sweetened by high fructose corn syrup the sweetener commonly found in soft drinks a second group will get beverages sweetened by the artificial sweetener aspartame to other groups will get the same drinks but they will be allowed to eat as much food as they'd like the idea is to see if high fructose corn syrup causes cardiovascular problems and if weight gain is the morse high fructose corn syrup is the sweetener used in the majority of those so-called sugary drinks like soda it was invented in one thousand nine hundred seventy one by japanese scientists took a saki. the scientists from japan took corn starch and they added. enzyme or acid to turn it into a glucose syrup the scientists in japan added another and zein and that turned a bunch of the glucose is in the glucose syrup into fructose since narrow you have a very sweet fructose are up. you can add that glucose syrup and that fructose syrup together and get any kind of combination of glucose to fructose that you want the beverage industry began using high fructose corn syrup in one thousand nine hundred eighty because it is twenty to seventy percent less expensive than sugar that's when consumption of soda began to soar according to the u.s. department of agriculture from one thousand nine hundred eighty to two thousand consumption went up by forty percent to four hundred forty cans of soda a year per person in india sales increased ten percent a year since one thousand nine hundred ninety eight now up to eleven leaders per person each year also in the one nine hundred eighty s. supersizing begin scientists say that's when obesity diabetes and heart disease rates went up. so what does it take to pull off a study like this well for starters it takes food and a lot of it now this package contains a fourth pre-prepared meals how it's divided is determined by the research team but we're talking about breakfast lunch and dinner all prepared for each and every one of the subjects that equals two hundred and ten individual meals per person over a ten week period. garlock you can post their sugar beverage. there. it is the final night of the study this is what dinner looks like in a science lab. everything from the main course to the sugary beverage has been measured and recorded the amount of sweetener a subject is given comes in the drink the food supplies the daily intake of calories you lor will get to enjoy his meal. then like the other subjects he will be tested with a device that measures how fast his body burns fat on this diet no exercise is allowed that would burn calories and skew results. ok ok it's simply measuring oxygen consumption and c o two production through your breath yes so all's you're doing is putting a face mask on our subjects with a long list that leads from their mouth. to the analyzer. and so it's a c o two carbon dioxide and oxygen analyzer so it's just taking the air that the subjects is exhaling and telling us ok this much oxygen this much c o two and from there then we do production and consumption values from bad. fat burning it's technically called fat oxidation can be calculated this test will determine if fat burning in the liver is impaired when the liver is overloaded with the sugar creek talks there will be one more test tonight. each of the subjects blood will be drawn to vials worth. and taken to the lab first sophisticated round of blood analysis. some just removing this bottom layer which contains or lifted french dr candice price is in charge of the liquids lab libyans are fats found in the blood her work is key to the study for here in the lab your job is to look at the blood of the study subjects and determine whether or not there's fat present cannot lead right now show me how some of this process thanks the work requires a steady hand blood samples are reduced to components and separated into the different fats scientists are focusing on including cholesterol which to this institute is one subject from one time point there are thousands of blood samples that require meticulous care and so for example this is drop twenty five meaning at. one of the time points drop twenty five blood was taken and this one. isn't that time for one person from one person each person in the study will have blood drawn two hundred twenty six times over the course of the study once the samples are prepared dr pryce will use what's called a capillary tube to spread the liquid across the glass plate her number these your lab right now. and repeat that across the four lines here right for the final step in the process some special effects are needed ok so someone can keep the lights for me. ok. and this is a u.v. light which will allow us to see the fluorescent spray that with the fluorescent dye which is what will allow us to say that ok about the dye we can't see anything so here this bottom fraction is the free quest for all and as we move up the plate we see the triglyceride fraction here. at the very top with the plates which doesn't seem to be quite as abundant in this particular so samples but here we see the questionable history so those are three liberties that are really important for arthrosclerosis which is exactly a risk factor yes the plates work much like a chart that allows researchers to see what kind of cardiovascular risk may be coming from the sweetener by the time the study is completed we'll have a strong database to work from but the effects of the sweetener can be detected almost immediately so how quickly do you do you see the results in the people well we know for sure from our previous study our second and i age funded study it was only two weeks long our average subject their age was twenty five two weeks and you saw an increase in what. the respect for cardiovascular disease this study we called our dose response study because we actually fed four levels of high fructose corn syrup zero. ten percent seventeen and a half percent and twenty five percent of energy requirement and we saw. a dose perfect stairstep response for cholesterol for triglycerides. for your acid so as you increased the intake your risk factors and right to take in in la and what was very important was that even the ten percent group showed increases. significant increases compared to their baseline level that was only a quibble and tell him be a written there are research subjects one and a half cans of soda a day so basically a half a can of breakfast a half a can lunch a half a can a dinner was the equivalent. again a surprise i would not have expected to see significant increases in wrist factors with only a half a can per meal but in two weeks i would have believed it could have happened in six months but i didn't know we would see it so quickly the study group that drink an artificial sweetener aspartame instead of high fructose corn syrup experienced none of those risk factors what causes the increase in cardiovascular risk back in radiology dr mcginn explained how high fructose corn syrup affects the body. so the anatomy that we're really looking at is a structure here which is the liver ok and what we do we take specialized samurai to barracks and were able to calibrate the exact amount of fat within the liver which is important to the study and what we see here is two different sets of factor we call this the subcutaneous fat this would be this sort of fat that somebody could pinch on somebody if you wanted to but then inside the muscle here we have the visceral fat so this whole pad is the white structure we see here so we're trying to look at the difference between the bistro fat and the sub teeniest that there are differences in. the health risks of deposition subcutaneous first as visceral yes so we found it in the study patients proved toads diets bait and actually forming more visceral fat and so. continues found so that some to this study and then there's other metabolic events that we've found out of what we think of found as fact but actually in this study that isn't all the same so your study was the first one to show that what you eat can impact where fat is deposited on the body whether it's like the fat here versus fat elsewhere is that right. to the best of my knowledge yes we were the first and that's important because we know for sure there's a big difference between the a facts of where our fat is stored and. it's our health and why why is fructose so much worse that is such an important question the enzyme for fructose is not in communication with the liver in fact it's always turned on it's always working hard therefore pretty much every single fructose molecule that goes through the liver via the portal vein gets pulled in the liver and gets sent down the metabolic pathway the liver does the best it can using all this fructose when there's still too much substrate around the liver then turns it into fact in our ancestors it was easy there wasn't much fructose around no problem but now we have great big thirty two and so does that overloads the liver with fructose so now what happens with this fat well the first thing extra fat in the liver does is cause the liver to send it out into the blood it sends it out into with little packages that include lots and lots of triglycerides but also includes cholesterol immediately blood trying. rides go up but eventually the cluster levels go up so high fructose corn syrup appears to be behind these problems but dr stan hope says sucrose any sugar made from sugar cane or sugar beet may also increase liver fat she suggests limiting intake of all types of sugars and sweeteners brown white or artificial the best advice is to stick with mother nature .

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