A new Editor-in-Chief for PLOS ONE PLOS ONE community, What a joy it is to write this letter – to have the opportunity to reflect on the strengths of PLOS ONE and consider how we can best meet your needs in the years ahead. I’m writing to you to share what you can expect from me as Editor-in-Chief of PLOS ONE, and to call for your feedback and your perspective on what we’ve gotten right, and where we can improve. I am a molecular biologist by training. I received my PhD in Genetics and Molecular Biology from the University of North Carolina at Chapel Hill in 2004, and studied gene expression signatures in lung cancer cells while a postdoc at Duke University. As a brand-new postdoc I had the experience that I am sure will be familiar to many of you of writing grants to secure funding for my research – and I realised, during this process, that what I really loved about scientific research was not the process of making the discoveries myself, but reading papers and considering how pieces of research fit together to advance discoveries. So, in 2007, I left the lab to begin working in science publishing. I joined