One of the shining jewels of UC San Francisco’s research program has received a $25 million gift that will ensure the success of its daring mission for many years to come. The newly named Sandler Program for Breakthrough Biomedical Research – previously known as the Program in Breakthrough Biomedical Research (PBBR) – has for 23 years supported the boldest, least explored research ideas in the life sciences. The program, the brainchild of Nobel laureate and former UCSF Chancellor J. Michael Bishop, MD, is unconventional in its audacity, simplicity, and speed: PBBR applicants are asked to describe their most adventurous idea for a research project, in two pages or less, and in return they receive a funding decision within 30 days.