5 Best CBD Oils for Seizures Amanda Gardner Replay Video A CBD breakthrough In 2018, the Food and Drug Administration (FDA) made history when it approved the first CBD (cannabidiol) drug. Although Epidiolex was specifically approved to treat two rare forms of epilepsy—Lennox-Gastaut syndrome and Dravet syndrome—doctors also prescribe it off label to successfully treat many other forms of epilepsy. Even beyond this one prescription medication, many people with seizures claim that CBD has benefited them. This is what you need to know about CBD products, epilepsy, and seizures. What is CBD? CBD is one of two main active ingredients found in both the cannabis plant and the related hemp plant. The other main active ingredient is delta-9-tetrahydrocannabinol (THC) best known for causing a high. By contrast, CBD does not make you high, though it appears to have other effects on the body. (Learn more about the differences between CBD and THC.)