Feb 25, 2021
Associations finally demonstrated in a large, diverse population
Diets with a high glycemic index are associated with an increased risk of both cardiovascular disease (CVD) and death, according to results from the large, international Prospective Urban Rural Epidemiology (PURE) study, published in
Previous studies on the associations between glycemic index and cardiovascular disease and risk have shown mixed results and have been primarily conducted in participants from high-income Western populations. To rectify this, David J.A. Jenkins, MD, PhD, of the University of Toronto, Ontario, Canada, and fellow PURE study investigators, conducted this study.
“We have assessed the association between the glycemic index and cardiovascular disease and all-cause mortality in the large, international [PURE] study involving participants with a broad range of carbohydrate intakes and diverse dietary patterns. We hypothesized that such a study would be most likely to indicate th
A total of 137,851 people aged 35 to 70 years old were followed for a median of 9.5 years through the Population Urban and Rural Epidemiology (PURE) study run by the Population Health Research Institute (PHRI) of McMaster University and Hamilton Health Sciences.